3M45
 
 | | Crystal structure of Ig1 domain of mouse SynCAM 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 2 | | 著者 | Yue, L, Modis, Y. | | 登録日 | 2010-03-10 | | 公開日 | 2010-09-08 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion.
J.Biol.Chem., 285, 2010
|
|
5VSL
 | | Crystal structure of viperin with bound [4Fe-4S] cluster and S-adenosylhomocysteine (SAH) | | 分子名称: | IRON/SULFUR CLUSTER, Radical S-adenosyl methionine domain-containing protein 2, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E. | | 登録日 | 2017-05-11 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.972 Å) | | 主引用文献 | Structural studies of viperin, an antiviral radical SAM enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5VSM
 | | Crystal structure of viperin with bound [4Fe-4S] cluster, 5'-deoxyadenosine, and L-methionine | | 分子名称: | 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ... | | 著者 | Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E. | | 登録日 | 2017-05-11 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural studies of viperin, an antiviral radical SAM enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
9F3P
 | | Cryo-EM structure of the A946T MDA5-dsRNA filament | | 分子名称: | Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), RNA (5'-R(P*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*GP*AP*C)-3'), ... | | 著者 | Singh, R, Herrero del Valle, A, Modis, Y. | | 登録日 | 2024-04-25 | | 公開日 | 2025-02-26 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | | 主引用文献 | Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
|
|
9F2W
 | | Cryo-EM structure of the I923V MDA5-dsRNA filament in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ... | | 著者 | Singh, R, Herrero del Valle, A, Modis, Y. | | 登録日 | 2024-04-24 | | 公開日 | 2025-02-26 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (4.21 Å) | | 主引用文献 | Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
|
|
9F2L
 | | Cryo-EM structure of the I923V MDA5-dsRNA filament with ADP-AlF4 bound and 73-degree helical twist | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ... | | 著者 | Singh, R, Herrero del Valle, A, Modis, Y. | | 登録日 | 2024-04-23 | | 公開日 | 2025-02-26 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | | 主引用文献 | Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
|
|
9F20
 | | Cryo-EM structure of the I923V MDA5-dsRNA filament with ADP-AlF4 bound and 88-degree helical twist | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), ... | | 著者 | Singh, R, Herrero del Valle, A, Modis, Y. | | 登録日 | 2024-04-20 | | 公開日 | 2025-02-26 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | | 主引用文献 | Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
|
|
9F1U
 | | Cryo-EM structure of the I923V MDA5-dsRNA filament with ADP-AlF4 bound and 81-degree helical twist | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ... | | 著者 | Singh, R, Herrero del Valle, A, Modis, Y. | | 登録日 | 2024-04-20 | | 公開日 | 2025-02-26 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
|
|
9F0J
 | | Cryo-EM structure of the I923V MDA5-dsRNA filament without nucleotide | | 分子名称: | Interferon-induced helicase C domain-containing protein 1, RNA (5'-CGUCAUGCGCAUGGA-3'), RNA (5'-UCCAUGCGCAUGACG-3'), ... | | 著者 | Singh, R, Herrero del Valle, A, Modis, Y. | | 登録日 | 2024-04-16 | | 公開日 | 2025-02-26 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
|
|
3NEC
 | | Crystal Structure of Toxoplasma gondii Profilin | | 分子名称: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Inflammatory profilin, SULFATE ION | | 著者 | Kucera, K, Modis, Y. | | 登録日 | 2010-06-08 | | 公開日 | 2010-09-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11.
J.Mol.Biol., 403, 2010
|
|
8P0E
 | |
8P0C
 | |
8QFB
 | |
6T1B
 | |
6T0Y
 | |
7NIQ
 | |
7NIC
 | |
7NGA
 | |
1RH5
 | | The structure of a protein conducting channel | | 分子名称: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | | 著者 | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | | 登録日 | 2003-11-13 | | 公開日 | 2004-01-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | X-ray structure of a protein-conducting channel
Nature, 427, 2004
|
|
7BKQ
 | |
7BKP
 | | CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ... | | 著者 | Singh, R, Herrero del Valle, A, Yu, Q, Modis, Y. | | 登録日 | 2021-01-16 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
|
|
1RHZ
 | | The structure of a protein conducting channel | | 分子名称: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | | 著者 | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | | 登録日 | 2003-11-15 | | 公開日 | 2004-01-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | X-ray structure of a protein-conducting channel.
Nature, 427, 2004
|
|
4JNT
 | |
4HJ1
 | |
4HJC
 | |
