3CW1
 
 | | Crystal Structure of Human Spliceosomal U1 snRNP | | 分子名称: | Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, ... | | 著者 | Pomeranz Krummel, D.A, Oubridge, C, Leung, A.K, Li, J, Nagai, K. | | 登録日 | 2008-04-21 | | 公開日 | 2009-03-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (5.493 Å) | | 主引用文献 | Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.
Nature, 458, 2009
|
|
4KIT
 | | Crystal structure of human Brr2 in complex with the Prp8 Jab1/MPN domain | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, ... | | 著者 | Wahl, M.C, Wandersleben, T, Santos, K.F. | | 登録日 | 2013-05-02 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.598 Å) | | 主引用文献 | Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8.
Science, 341, 2013
|
|
4NHO
 | | Structure of the spliceosomal DEAD-box protein Prp28 | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, MERCURY (II) ION, ... | | 著者 | Moehlmann, S, Neumann, P, Ficner, R. | | 登録日 | 2013-11-05 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
6FF7
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
|
|
6FF4
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2018-08-29 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
|
|
5HY7
 | |
5O9Z
 | |
2OG4
 | |
1B34
 | | CRYSTAL STRUCTURE OF THE D1D2 SUB-COMPLEX FROM THE HUMAN SNRNP CORE DOMAIN | | 分子名称: | PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1), PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2) | | 著者 | Walke, S, Young, R.J, Kambach, C, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K. | | 登録日 | 1998-12-17 | | 公開日 | 2000-01-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs.
Cell(Cambridge,Mass.), 96, 1999
|
|
1D3B
 | | CRYSTAL STRUCTURE OF THE D3B SUBCOMPLEX OF THE HUMAN CORE SNRNP DOMAIN AT 2.0A RESOLUTION | | 分子名称: | CITRIC ACID, GLYCEROL, PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN ASSOCIATED PROTEIN B), ... | | 著者 | Kambach, C, Walke, S, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K. | | 登録日 | 1998-12-22 | | 公開日 | 1999-12-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs.
Cell(Cambridge,Mass.), 96, 1999
|
|
5LTA
 | |
5LTK
 | |
5LTJ
 | | Crystal structure of the Prp43-ADP-BeF3 complex (in orthorhombic space group) | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Tauchert, M.J, Ficner, R. | | 登録日 | 2016-09-06 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural insights into the mechanism of the DEAH-box RNA helicase Prp43.
Elife, 6, 2017
|
|
4F91
 | | Brr2 Helicase Region | | 分子名称: | U5 small nuclear ribonucleoprotein 200 kDa helicase | | 著者 | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | | 登録日 | 2012-05-18 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | | 主引用文献 | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
6EN4
 | | SF3b core in complex with a splicing modulator | | 分子名称: | PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... | | 著者 | Cretu, C, Pena, V. | | 登録日 | 2017-10-04 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds.
Mol. Cell, 70, 2018
|
|
4F93
 | | Brr2 Helicase Region S1087L, Mg-ATP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | | 登録日 | 2012-05-18 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4F92
 | | Brr2 Helicase Region S1087L | | 分子名称: | SULFANILAMIDE, U5 small nuclear ribonucleoprotein 200 kDa helicase | | 著者 | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | | 登録日 | 2012-05-18 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.662 Å) | | 主引用文献 | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4YHV
 | | Yeast Prp3 C-terminal fragment 325-469 | | 分子名称: | ACETIC ACID, U4/U6 small nuclear ribonucleoprotein PRP3 | | 著者 | Liu, S, Wahl, M.C. | | 登録日 | 2015-02-27 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing.
Elife, 4, 2015
|
|
4YHU
 | | Yeast Prp3 C-terminal fragment 296-469 | | 分子名称: | U4/U6 small nuclear ribonucleoprotein PRP3, YTTRIUM (III) ION | | 著者 | Liu, S, Wahl, M.C. | | 登録日 | 2015-02-27 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing.
Elife, 4, 2015
|
|
4YHW
 | |
3TP2
 | |
7ABH
 | | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | | 分子名称: | Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-07 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
|
|
7ABI
 | | Human pre-Bact-2 spliceosome | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-07 | | 公開日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
|
|
7AAV
 | | Human pre-Bact-2 spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-04 | | 公開日 | 2020-12-09 | | 最終更新日 | 2020-12-30 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
|
|
7ABF
 | | Human pre-Bact-1 spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-07 | | 公開日 | 2020-12-09 | | 最終更新日 | 2020-12-30 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
|
|
