7P57
| VSG2 mutant structure lacking the calcium binding pocket | 分子名称: | Variant surface glycoprotein MITAT 1.2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N. | 登録日 | 2021-07-14 | 公開日 | 2022-07-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.961 Å) | 主引用文献 | Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42, 2023
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7P59
| Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) with two O-linked post-translational modifications | 分子名称: | Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Gkeka, A, Arest-Branco, F, Stebbins, C.E, Papavasiliou, F.N. | 登録日 | 2021-07-14 | 公開日 | 2022-07-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42, 2023
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7P5B
| Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) mutant (serine 319 to alanine), single O-linked glycosylated at Ser317 | 分子名称: | Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N. | 登録日 | 2021-07-14 | 公開日 | 2022-07-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42, 2023
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7P5A
| Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) mutant (serine 317 to alanine), single O-linked glycosylated at Ser319 | 分子名称: | Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N. | 登録日 | 2021-07-14 | 公開日 | 2022-07-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42, 2023
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6ELC
| Crystal Structure of O-linked Glycosylated VSG3 | 分子名称: | Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Stebbins, C.E. | 登録日 | 2017-09-28 | 公開日 | 2018-07-11 | 最終更新日 | 2022-03-30 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat. Nat Microbiol, 3, 2018
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5VI8
| Structure of a mycobacterium smegmatis transcription initiation complex with an upstream-fork promoter fragment | 分子名称: | 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... | 著者 | Hubin, E.A, Campbell, E.A, Darst, S.A. | 登録日 | 2017-04-14 | 公開日 | 2017-04-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures. Nat Commun, 8, 2017
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8E74
| Mycobacterium tuberculosis RNAP paused elongation complex with NusG transcription factor | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Delbeau, M, Darst, S.A, Campbell, E.A. | 登録日 | 2022-08-23 | 公開日 | 2023-03-22 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis. Mol.Cell, 83, 2023
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8E82
| Mycobacterium tuberculosis RNAP elongation complex with NusG transcription factor | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Delbeau, M, Darst, S.A, Campbell, E.A. | 登録日 | 2022-08-25 | 公開日 | 2023-03-22 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis. Mol.Cell, 83, 2023
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8E79
| Mycobacterium tuberculosis RNAP paused elongation complex with Escherichia coli NusG transcription factor | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Delbeau, M, Darst, S.A, Campbell, E.A. | 登録日 | 2022-08-23 | 公開日 | 2023-03-22 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis. Mol.Cell, 83, 2023
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8E95
| Mycobacterium tuberculosis RNAP elongation complex | 分子名称: | DNA (25-MER), DNA (33-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Delbeau, M, Darst, S.A, Campbell, E.A. | 登録日 | 2022-08-26 | 公開日 | 2023-03-22 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis. Mol.Cell, 83, 2023
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8E8M
| Mycobacterium tuberculosis RNAP paused elongation complex | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Delbeau, M, Darst, S.A, Campbell, E.A. | 登録日 | 2022-08-25 | 公開日 | 2023-03-22 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis. Mol.Cell, 83, 2023
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6BZO
| Mtb RNAP Holo/RbpA/Fidaxomicin/upstream fork DNA | 分子名称: | DNA (26-MER), DNA (32-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. | 登録日 | 2017-12-25 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
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4YX7
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4YXC
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4YXA
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4YX5
| SpaO(SPOA1,2) | 分子名称: | CHLORIDE ION, Surface presentation of antigens protein SpaO | 著者 | Notti, R.Q, Stebbins, C.E. | 登録日 | 2015-03-22 | 公開日 | 2015-06-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.9001 Å) | 主引用文献 | A common assembly module in injectisome and flagellar type III secretion sorting platforms. Nat Commun, 6, 2015
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4YX1
| SpaO(SPOA2) | 分子名称: | CALCIUM ION, Surface presentation of antigens protein SpaO | 著者 | Notti, R.Q, Stebbins, C.E. | 登録日 | 2015-03-21 | 公開日 | 2015-06-03 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | A common assembly module in injectisome and flagellar type III secretion sorting platforms. Nat Commun, 6, 2015
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4YXB
| FliM(SPOA)::FliN fusion protein | 分子名称: | Ambiguous peptide density, Flagellar motor switch protein FliM,Flagellar motor switch protein FliN, FliM::FliN fragment, ... | 著者 | Notti, R.Q, Stebbins, C.E. | 登録日 | 2015-03-22 | 公開日 | 2015-06-03 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | A common assembly module in injectisome and flagellar type III secretion sorting platforms. Nat Commun, 6, 2015
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