7P57

VSG2 mutant structure lacking the calcium binding pocket

Summary for 7P57

Entry DOI	10.2210/pdb7p57/pdb
Related	1VSG 7P56 7P59 7P5A 7P5B 7P5D
Descriptor	Variant surface glycoprotein MITAT 1.2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	variant surface glycoprotein, coat, trypanosoma brucei, african trypanosome, immune evasion, antigenic variation, calcium binding, calcium, membrane protein
Biological source	Trypanosoma brucei brucei
Total number of polymer chains	1
Total formula weight	51720.07
Authors	Gkeka, A.,Aresta-Branco, F.,Stebbins, C.E.,Papavasiliou, F.N. (deposition date: 2021-07-14, release date: 2022-07-27, Last modification date: 2024-02-07)
Primary citation	Gkeka, A.,Aresta-Branco, F.,Triller, G.,Vlachou, E.P.,van Straaten, M.,Lilic, M.,Olinares, P.D.B.,Perez, K.,Chait, B.T.,Blatnik, R.,Ruppert, T.,Verdi, J.P.,Stebbins, C.E.,Papavasiliou, F.N. Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42:112262-112262, 2023 Cited by PubMed: 36943866 DOI: 10.1016/j.celrep.2023.112262 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.961 Å)

Structure validation