7P59
Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) with two O-linked post-translational modifications
Summary for 7P59
Entry DOI | 10.2210/pdb7p59/pdb |
Related | 7P56 7P57 7P5A 7P5B 7P5D |
Descriptor | Variant surface glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | variant surface glycoprotein, coat, trypanosoma brucei, o-glycosylation, o-glycans, immune evasion, african trypanosome, antigenic variation, post-translational modification, vsg, parasite, sleeping sickness, membrane protein |
Biological source | Trypanosoma brucei brucei |
Total number of polymer chains | 1 |
Total formula weight | 55367.67 |
Authors | Gkeka, A.,Arest-Branco, F.,Stebbins, C.E.,Papavasiliou, F.N. (deposition date: 2021-07-14, release date: 2022-07-27, Last modification date: 2024-02-07) |
Primary citation | Gkeka, A.,Aresta-Branco, F.,Triller, G.,Vlachou, E.P.,van Straaten, M.,Lilic, M.,Olinares, P.D.B.,Perez, K.,Chait, B.T.,Blatnik, R.,Ruppert, T.,Verdi, J.P.,Stebbins, C.E.,Papavasiliou, F.N. Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42:112262-112262, 2023 Cited by PubMed: 36943866DOI: 10.1016/j.celrep.2023.112262 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.27 Å) |
Structure validation
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