8E8M
Mycobacterium tuberculosis RNAP paused elongation complex
Summary for 8E8M
Entry DOI | 10.2210/pdb8e8m/pdb |
EMDB information | 27944 |
Descriptor | DNA (54-MER), RNA (42-MER), DNA-directed RNA polymerase subunit alpha, ... (9 entities in total) |
Functional Keywords | rna polymerase, transcription factor, elongation, pausing, transcription-transferase-dna complex, transcription-dna-rna complex, transcription/dna/rna |
Biological source | Mycobacterium tuberculosis More |
Total number of polymer chains | 8 |
Total formula weight | 410548.25 |
Authors | Delbeau, M.,Darst, S.A.,Campbell, E.A. (deposition date: 2022-08-25, release date: 2023-03-22, Last modification date: 2023-10-11) |
Primary citation | Delbeau, M.,Omollo, E.O.,Froom, R.,Koh, S.,Mooney, R.A.,Lilic, M.,Brewer, J.J.,Rock, J.,Darst, S.A.,Campbell, E.A.,Landick, R. Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis. Mol.Cell, 83:1474-1488.e8, 2023 Cited by PubMed: 37116494DOI: 10.1016/j.molcel.2023.04.007 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.13 Å) |
Structure validation
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