6ELC

Crystal Structure of O-linked Glycosylated VSG3

Summary for 6ELC

Entry DOI	10.2210/pdb6elc/pdb
Descriptor	Variant surface glycoprotein, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-glucopyranose, ... (4 entities in total)
Functional Keywords	trypanosome, vsg, sleeping sickness, antigen, immune system
Biological source	Trypanosoma brucei brucei
Total number of polymer chains	1
Total formula weight	54863.23
Authors	Stebbins, C.E. (deposition date: 2017-09-28, release date: 2018-07-11, Last modification date: 2022-03-30)
Primary citation	Pinger, J.,Nesic, D.,Ali, L.,Aresta-Branco, F.,Lilic, M.,Chowdhury, S.,Kim, H.S.,Verdi, J.,Raper, J.,Ferguson, M.A.J.,Papavasiliou, F.N.,Stebbins, C.E. African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat. Nat Microbiol, 3:932-938, 2018 Cited by PubMed: 29988048 DOI: 10.1038/s41564-018-0187-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.41 Å)

Structure validation