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1CQ0
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SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B'SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B '
分子名称: PROTEIN (NEW HYPOTHALAMIC NEUROPEPTIDE/OREXIN-B28)
著者Lee, K.-H, Bang, E.J, Chae, K.-J, Lee, D.W, Lee, W.
登録日1999-08-04
公開日2000-01-10
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B.
Eur.J.Biochem., 266, 1999
8HU2
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Rattus Syntenin-1 PDZ domain with inhibitor
分子名称: (2~{S})-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)-3-(4-oxidanylidene-5~{H}-pyrimidin-2-yl)propanoic acid, Syntenin-1
著者Heo, Y, Lee, J, Yun, J.H, Lee, W.
登録日2022-12-22
公開日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of STNPDZ with inhibitor at 1.60 Angstroms resolution.
To Be Published
1RJA
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BU of 1rja by Molmil
Solution Structure and Backbone Dynamics of the Nonreceptor Tyrosine Kinase PTK6/Brk SH2 Domain
分子名称: Tyrosine-protein kinase 6
著者Hong, E, Shin, J, Lee, W.
登録日2003-11-18
公開日2004-07-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Structure and Backbone Dynamics of the Non-receptor Protein-tyrosine Kinase-6 Src Homology 2 Domain
J.Biol.Chem., 279, 2004
7LHQ
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BU of 7lhq by Molmil
Solution structure of SARS-CoV-2 nonstructural protein 7 at pH 7.0
分子名称: Non-structural protein 7
著者Lee, Y, Tonelli, M, Anderson, T.K, Kirchdoerfer, R.N, Henzler-Wildman, K, Lee, W.
登録日2021-01-26
公開日2022-02-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献pH-dependent polymorphism of the structure of SARS-CoV-2 nsp7
Biorxiv, 2021
1RYJ
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BU of 1ryj by Molmil
Solution NMR Structure of Protein Mth1743 from Methanobacterium thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH1743_1_70; Northeast Structural Genomics Consortium Target TT526.
分子名称: unknown
著者Yee, A, Chang, X, Pineda-Lucena, A, Wu, B, Semesi, A, Le, B, Ramelot, T, Lee, G.M, Bhattacharyya, S, Gutierrez, P, Denisov, A, Lee, C.H, Cort, J.R, Kozlov, G, Liao, J, Finak, G, Chen, L, Wishart, D, Lee, W, McIntosh, L.P, Gehring, K, Kennedy, M.A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
登録日2003-12-22
公開日2004-02-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献AN NMR APPROACH TO STRUCTURAL PROTEOMICS
Proc.Natl.Acad.Sci.USA, 99, 2002
6OCV
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BU of 6ocv by Molmil
Solution structure of the H-NOX protein from Shewanella woodyi in the Fe(II)CO ligation state
分子名称: CARBON MONOXIDE, Heme NO binding domain protein, PROTOPORPHYRIN IX CONTAINING FE
著者Chen, C.Y, Lee, W, Montfort, W.R.
登録日2019-03-25
公開日2020-05-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of the Shewanella woodyi H-NOX protein in the presence and absence of soluble guanylyl cyclase stimulator IWP-051.
Protein Sci., 30, 2021
1EJQ
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BU of 1ejq by Molmil
SOLUTION STRUCTURE OF THE SYNDECAN-4 WHOLE CYTOPLASMIC DOMAIN IN THE PRESENCE OF PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE
分子名称: SYNDECAN-4
著者Shin, J, Oh, E.S, Lee, D, Couchman, J.R, Lee, W.
登録日2000-03-04
公開日2001-03-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献SOLUTION STRUCTURE OF THE SYNDECAN-4 WHOLE CYTOPLASMIC DOMAIN IN THE PRESENCE OF PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE
To be Published
1EJP
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BU of 1ejp by Molmil
SOLUTION STRUCTURE OF THE SYNDECAN-4 WHOLE CYTOPLASMIC DOMAIN
分子名称: SYNDECAN-4
著者Lee, D, Oh, E.S, Woods, A, Couchman, J.R, Lee, W.
登録日2000-03-03
公開日2001-09-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the dimeric cytoplasmic domain of syndecan-4.
Biochemistry, 40, 2001
2HQR
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BU of 2hqr by Molmil
Structure of a Atypical Orphan Response Regulator Protein Revealed a New Phosphorylation-Independent Regulatory Mechanism
分子名称: Putative TRANSCRIPTIONAL REGULATOR
著者Hong, E, Lee, W.
登録日2006-07-19
公開日2007-05-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of an Atypical Orphan Response Regulator Protein Supports a New Phosphorylation-independent Regulatory Mechanism
J.Biol.Chem., 282, 2007
2HQO
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BU of 2hqo by Molmil
Structure of a Atypical Orphan Response Regulator Protein Revealed a New Phosphorylation-Independent Regulatory Mechanism
分子名称: Putative TRANSCRIPTIONAL REGULATOR
著者Hong, E, Lee, W.
登録日2006-07-19
公開日2007-05-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of an Atypical Orphan Response Regulator Protein Supports a New Phosphorylation-independent Regulatory Mechanism
J.Biol.Chem., 282, 2007
2HQN
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BU of 2hqn by Molmil
Structure of a Atypical Orphan Response Regulator Protein Revealed a New Phosphorylation-Independent Regulatory Mechanism
分子名称: Putative TRANSCRIPTIONAL REGULATOR
著者Hong, E, Lee, W.
登録日2006-07-19
公開日2007-05-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of an Atypical Orphan Response Regulator Protein Supports a New Phosphorylation-independent Regulatory Mechanism
J.Biol.Chem., 282, 2007
8Y4Z
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BU of 8y4z by Molmil
Monomeric HERC5 HECT c-lobe structure in solution
分子名称: E3 ISG15--protein ligase HERC5
著者Dag, C, Lambert, M, Kahraman, K, Lohn, F, Lee, W, Gocenler, O, Guntert, P, Dotsch, V.
登録日2024-01-31
公開日2024-02-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Monomeric HERC5 HECT c-lobe structure in solution
To Be Published
8WWX
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BU of 8wwx by Molmil
Ube1L acts akin to a mitt, that mediates UbcH8 binding and orchestrates "E1-E2" interaction
分子名称: Ubiquitin-like modifier-activating enzyme 7
著者Dag, C, Elgin, E.S, Lee, W, Ziarek, J.J.
登録日2023-10-27
公開日2023-11-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ube1L acts akin to a mitt, that mediates UbcH8 binding and orchestrates "E1-E2" interaction
To Be Published
6T8W
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BU of 6t8w by Molmil
Complement factor B in complex with (-)-4-(1-((5,7-Dimethyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic acid
分子名称: 5,7-dimethyl-4-[[(2~{S})-2-phenylpiperidin-1-yl]methyl]-1~{H}-indole, Complement factor B, SULFATE ION, ...
著者Mainolfi, N, Ehara, T, Karki, R.G, Anderson, K, Sweeney, A.M, Wiesmann, C, Adams, C, Mainolfi, N, Liao, S.M, Argikar, U.A, Jendza, K, Zhang, C, Powers, J, Klosowski, D.W, Crowley, M, Kawanami, T, Ding, J, April, M, Forster, C, Wu, M.S, Capparelli, M, Ramqaj, R, Solovay, C, Cumin, F, Smith, T.M, Ferrara, L, Lee, W, Long, D, Prentiss, M, Erkenez, A.D, Yang, L, Fang, L, Sellner, H, Sirockin, F, Valeur, E, Erbel, P, Ramage, P, Gerhartz, B, Schubart, A, Flohr, S, Gradoux, N, Feifel, R, Vogg, B, Wiesmann, C, Maibaum, J, Eder, J, Sedrani, R, Harrison, R.A, Mogi, M, Jaffee, B.D, Adams, C.M.
登録日2019-10-25
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.
J.Med.Chem., 63, 2020
6T8U
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BU of 6t8u by Molmil
Complement factor B in complex with 5-Bromo-3-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-7-methyl-1H-indol-4-amine
分子名称: 5-bromanyl-3-chloranyl-~{N}-(1~{H}-imidazol-2-yl)-7-methyl-1~{H}-indol-4-amine, Complement factor B, SULFATE ION
著者Mainolfi, N, Ehara, T, Karki, R.G, Anderson, K, Mac Sweeney, A, Wiesmann, C, Adams, C, Liao, S.-M, Argikar, U.A, Jendza, K, Zhang, C, Powers, J, Klosowski, D.W, Crowley, M, Kawanami, T, Ding, J, April, M, Forster, C, Serrano-Wu, M, Capparelli, M, Ramqaj, R, Solovay, C, Cumin, F, Smith, T.M, Ferrara, L, Lee, W, Long, D, Prentiss, M, De Erkenez, A, Yang, L, Fang, L, Sellner, H, Sirockin, F, Valeur, E, Erbel, P, Ramage, P, Gerhartz, B, Schubart, A, Flohr, S, Gradoux, N, Feifel, R, Vogg, B, Maibaum, J, Eder, J, Sedrani, R, Harrison, R.A, Mogi, M, Jaffee, B.D, Adams, C.M.
登録日2019-10-25
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.
J.Med.Chem., 63, 2020
5ZTK
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BU of 5ztk by Molmil
Synchrotron structure of light-driven chloride pump having an NTQ motif
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Park, J.H, Park, S.Y, Lee, W.
登録日2018-05-04
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency
J. Biol. Chem., 294, 2019
4ZG0
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BU of 4zg0 by Molmil
Crystal structure of Mouse Syndesmos protein
分子名称: Protein syndesmos
著者Lee, I, Kim, H, Yoo, J, Cho, H, Lee, W.
登録日2015-04-22
公開日2016-04-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Crystal structure of syndesmos and its interaction with Syndecan-4 proteoglycan
Biochem.Biophys.Res.Commun., 463, 2015
5VSO
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BU of 5vso by Molmil
NMR structure of Ydj1 J-domain, a cytosolic Hsp40 from Saccharomyces cerevisiae
分子名称: Yeast dnaJ protein 1
著者Ciesielski, S.J, Tonelli, M, Lee, W, Cornilescu, G, Markley, J.L, Schilke, B.A, Ziegelhoffer, T, Craig, E.A.
登録日2017-05-12
公開日2017-11-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Broadening the functionality of a J-protein/Hsp70 molecular chaperone system.
PLoS Genet., 13, 2017
6T8V
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BU of 6t8v by Molmil
Complement factor B in complex with (S)-5,7-Dimethyl-4-((2-phenylpiperidin-1-yl)methyl)-1H-indole
分子名称: 4-[(2~{S})-1-[(5,7-dimethyl-1~{H}-indol-4-yl)methyl]piperidin-2-yl]benzoic acid, Complement factor B, SULFATE ION, ...
著者Mainolfi, N, Ehara, T, Karki, R.G, Anderson, K, Mac Sweeney, A, Wiesmann, C, Adams, C, Mainolfi, N, Liao, S.-M, Argikar, U.A, Jendza, K, Zhang, C, Powers, J, Klosowski, D.W, Crowley, M, Kawanami, T, Ding, J, April, M, Forster, C, Serrano-Wu, M, Capparelli, M, Ramqaj, R, Solovay, C, Cumin, F, Smith, T.M, Ferrara, L, Lee, W, Long, D, Prentiss, M, De Erkenez, A, Yang, L, Fang, L, Sellner, H, Sirockin, F, Valeur, E, Erbel, P, Ramage, P, Gerhartz, B, Schubart, A, Flohr, S, Gradoux, N, Feifel, R, Vogg, B, Wiesmann, C, Maibaum, J, Eder, J, Sedrani, R, Harrison, R.A, Mogi, M, Jaffee, B.D, Adams, C.M.
登録日2019-10-25
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.
J.Med.Chem., 63, 2020
5G1D
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BU of 5g1d by Molmil
The complex structure of syntenin-1 PDZ domain with c-terminal extension
分子名称: SYNDECAN-4, SYNTENIN-1
著者Lee, I, Kim, H, Yun, J.H, Lee, W.
登録日2016-03-25
公開日2016-11-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling.
Sci.Rep., 6, 2016
5G1E
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BU of 5g1e by Molmil
The complex structure of syntenin-1 PDZ domain with c-terminal extension
分子名称: SYNTENIN-1
著者Lee, I, Kim, H, Yun, J.H, Lee, W.
登録日2016-03-25
公開日2016-11-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling.
Sci.Rep., 6, 2016
5ZTL
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BU of 5ztl by Molmil
Non-cryogenic structure of light-driven chloride pump having an NTQ motif
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Park, S.Y, Liu, H, Lee, W.
登録日2018-05-04
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency
J. Biol. Chem., 294, 2019
1IQS
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BU of 1iqs by Molmil
Minimized average structure of MTH1880 from Methanobacterium Thermoautotrophicum
分子名称: MTH1880
著者Lee, C.H, Shin, J, Bang, E, Jung, J.W, Yee, A, Arrowsmith, C.H, Lee, W.
登録日2001-07-29
公開日2002-07-29
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a novel calcium binding protein, MTH1880, from Methanobacterium thermoautotrophicum.
Protein Sci., 13, 2004
1IQO
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Solution structure of MTH1880 from methanobacterium thermoautotrophicum
分子名称: HYPOTHETICAL PROTEIN MTH1880
著者Lee, C.H, Shin, J, Bang, E, Jung, J.W, Yee, A, Arrowsmith, C.H, Lee, W.
登録日2001-07-23
公開日2002-07-24
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a novel calcium binding protein, MTH1880, from Methanobacterium thermoautotrophicum.
Protein Sci., 13, 2004
2KCC
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BU of 2kcc by Molmil
Solution Structure of biotinoyl domain from human acetyl-CoA carboxylase 2
分子名称: Acetyl-CoA carboxylase 2
著者Lee, C, Cheong, H, Ryu, K, Lee, J, Lee, W, Jeon, Y, Cheong, C.
登録日2008-12-19
公開日2009-02-17
最終更新日2023-09-27
実験手法SOLUTION NMR
主引用文献Biotinoyl domain of human acetyl-CoA carboxylase: Structural insights into the carboxyl transfer mechanism.
Proteins, 72, 2008

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