7RFH
 
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7RGQ
 | | HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH GTP, ATP, IMP, NAD+; INTERFACE-CENTERED | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-15 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RGM
 | | HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH ATP, IMP, NAD+, OCTAMER-CENTERED | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-15 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RER
 | | HUMAN IMPDH1 TREATED WITH ATP, IMP, AND NAD+ | | 分子名称: | INOSINIC ACID, Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-13 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RGI
 | | HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH GTP, ATP, IMP, NAD+; INTERFACE-CENTERED | | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-15 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RES
 | | HUMAN IMPDH1 TREATED WITH ATP, IMP, AND NAD+, OCTAMER-CENTERED | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-13 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RFI
 | | HUMAN RETINAL VARIANT IMPDH1(595) TREATED WITH GTP, ATP, IMP, NAD+, INTERFACE-CENTERED | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-14 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RFG
 | | HUMAN IMPDH1 TREATED WITH GTP, IMP, AND NAD+ OCTAMER-CENTERED | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-14 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RFF
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7RFE
 | | HUMAN IMPDH1 TREATED WITH GTP, IMP, AND NAD+; INTERFACE-CENTERED | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-14 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RGD
 | | HUMAN RETINAL VARIANT IMPDH1(595) TREATED WITH GTP, ATP, IMP, NAD+, OCTAMER-CENTERED | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-15 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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8FOZ
 | | Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; filament assembly interface reconstruction | | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | O'Neill, A.G, Kollman, J.M. | | 登録日 | 2023-01-03 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2 Å) | | 主引用文献 | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
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8FUZ
 | | Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; filament assembly interface reconstruction | | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | O'Neill, A.G, Kollman, J.M. | | 登録日 | 2023-01-18 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | | 主引用文献 | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
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7JZV
 | | Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome | | 分子名称: | BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ... | | 著者 | Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E. | | 登録日 | 2020-09-02 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Nat.Struct.Mol.Biol., 28, 2021
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6IC4
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7UNG
 | | 48-nm repeat of the human respiratory doublet microtubule | | 分子名称: | Cilia- and flagella-associated protein 161, Cilia- and flagella-associated protein 20, Cilia- and flagella-associated protein 45, ... | | 著者 | Gui, M, Croft, J.T, Zabeo, D, Acharya, V, Kollman, J.M, Burgoyne, T, Hoog, J.L, Brown, A. | | 登録日 | 2022-04-11 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7UN1
 | | 8-nm repeat of the human sperm tip singlet microtubule | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Gui, M, Croft, J.T, Zabeo, D, Acharya, V, Kollman, J.M, Burgoyne, T, Hoog, J.L, Brown, A. | | 登録日 | 2022-04-08 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
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6BQW
 | | AlfA Filament bound to AMPPNP | | 分子名称: | Bacterial actin AlfA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Usluer, G.D, Kollman, J.M, DiMaio, F. | | 登録日 | 2017-11-28 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM structure of the bacterial actin AlfA reveals unique assembly and ATP-binding interactions and the absence of a conserved subdomain.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6PK4
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6PDT
 | | cryoEM structure of yeast glucokinase filament | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Glucokinase-1, MAGNESIUM ION, ... | | 著者 | Lynch, E.M, Dosey, A.M, Farrell, D.P, Stoddard, P.R, Kollman, J.M. | | 登録日 | 2019-06-19 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Polymerization in the actin ATPase clan regulates hexokinase activity in yeast.
Science, 367, 2020
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6PK7
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7MIG
 | | Human CTPS1 bound to inhibitor T35 | | 分子名称: | 2-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}-2-methyl-N-{5-[6-(trifluoromethyl)pyrazin-2-yl]pyridin-2-yl}propanamide, CTP synthase 1, GLUTAMINE, ... | | 著者 | Lynch, E.M, Dimattia, M.A, Kollman, J.M. | | 登録日 | 2021-04-16 | | 公開日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis for isoform-specific inhibition of human CTPS1.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MIF
 | | Human CTPS1 bound to inhibitor R80 | | 分子名称: | CTP synthase 1, GLUTAMINE, MAGNESIUM ION, ... | | 著者 | Lynch, E.M, Dimattia, M.A, Kollman, J.M. | | 登録日 | 2021-04-16 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis for isoform-specific inhibition of human CTPS1.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MIP
 | | Mouse CTPS1 bound to inhibitor R80 | | 分子名称: | CTP synthase 1, GLUTAMINE, MAGNESIUM ION, ... | | 著者 | Lynch, E.M, Dimattia, M.A, Kollman, J.M. | | 登録日 | 2021-04-17 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Structural basis for isoform-specific inhibition of human CTPS1.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MIV
 | | Mouse CTPS2-I250T bound to inhibitor R80 | | 分子名称: | CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... | | 著者 | Lynch, E.M, Dimattia, M.A, Kollman, J.M. | | 登録日 | 2021-04-17 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for isoform-specific inhibition of human CTPS1.
Proc.Natl.Acad.Sci.USA, 118, 2021
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