7MIV
Mouse CTPS2-I250T bound to inhibitor R80
Summary for 7MIV
Entry DOI | 10.2210/pdb7miv/pdb |
EMDB information | 23866 |
Descriptor | CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | glutaminase, amidoligase, nucleotide metabolism, ligase |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 4 |
Total formula weight | 266885.41 |
Authors | Lynch, E.M.,Dimattia, M.A.,Kollman, J.M. (deposition date: 2021-04-17, release date: 2021-10-13, Last modification date: 2024-05-29) |
Primary citation | Lynch, E.M.,DiMattia, M.A.,Albanese, S.,van Zundert, G.C.P.,Hansen, J.M.,Quispe, J.D.,Kennedy, M.A.,Verras, A.,Borrelli, K.,Toms, A.V.,Kaila, N.,Kreutter, K.D.,McElwee, J.J.,Kollman, J.M. Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 34583994DOI: 10.1073/pnas.2107968118 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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