7MIV

Mouse CTPS2-I250T bound to inhibitor R80

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000166	molecular_function	nucleotide binding
C	0003883	molecular_function	CTP synthase activity
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0006221	biological_process	pyrimidine nucleotide biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0016874	molecular_function	ligase activity
C	0016879	molecular_function	ligase activity, forming carbon-nitrogen bonds
C	0019856	biological_process	pyrimidine nucleobase biosynthetic process
C	0042802	molecular_function	identical protein binding
C	0044210	biological_process	'de novo' CTP biosynthetic process
C	0044281	biological_process	small molecule metabolic process
C	0046872	molecular_function	metal ion binding
C	0097268	cellular_component	cytoophidium
D	0000166	molecular_function	nucleotide binding
D	0003883	molecular_function	CTP synthase activity
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0006221	biological_process	pyrimidine nucleotide biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0016874	molecular_function	ligase activity
D	0016879	molecular_function	ligase activity, forming carbon-nitrogen bonds
D	0019856	biological_process	pyrimidine nucleobase biosynthetic process
D	0042802	molecular_function	identical protein binding
D	0044210	biological_process	'de novo' CTP biosynthetic process
D	0044281	biological_process	small molecule metabolic process
D	0046872	molecular_function	metal ion binding
D	0097268	cellular_component	cytoophidium
G	0000166	molecular_function	nucleotide binding
G	0003883	molecular_function	CTP synthase activity
G	0005524	molecular_function	ATP binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005829	cellular_component	cytosol
G	0006221	biological_process	pyrimidine nucleotide biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0016874	molecular_function	ligase activity
G	0016879	molecular_function	ligase activity, forming carbon-nitrogen bonds
G	0019856	biological_process	pyrimidine nucleobase biosynthetic process
G	0042802	molecular_function	identical protein binding
G	0044210	biological_process	'de novo' CTP biosynthetic process
G	0044281	biological_process	small molecule metabolic process
G	0046872	molecular_function	metal ion binding
G	0097268	cellular_component	cytoophidium
H	0000166	molecular_function	nucleotide binding
H	0003883	molecular_function	CTP synthase activity
H	0005524	molecular_function	ATP binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005829	cellular_component	cytosol
H	0006221	biological_process	pyrimidine nucleotide biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0016874	molecular_function	ligase activity
H	0016879	molecular_function	ligase activity, forming carbon-nitrogen bonds
H	0019856	biological_process	pyrimidine nucleobase biosynthetic process
H	0042802	molecular_function	identical protein binding
H	0044210	biological_process	'de novo' CTP biosynthetic process
H	0044281	biological_process	small molecule metabolic process
H	0046872	molecular_function	metal ion binding
H	0097268	cellular_component	cytoophidium

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {"description":"For GATase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00605","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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