7RGM

HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH ATP, IMP, NAD+, OCTAMER-CENTERED

Summary for 7RGM

• Entry DOI: 10.2210/pdb7rgm/pdb
• EMDB information: 24451 24452
• Descriptor: Inosine-5'-monophosphate dehydrogenase 1, ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... (4 entities in total)
• Functional Keywords: metabolism, filament, allostery, adenine, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 8
• Total formula weight: 483174.10

Authors

Burrell, A.L.,Kollman, J.M. (deposition date: 2021-07-15, release date: 2022-01-12, Last modification date: 2024-06-05)

• Primary citation: Burrell, A.L.,Nie, C.,Said, M.,Simonet, J.C.,Fernandez-Justel, D.,Johnson, M.C.,Quispe, J.,Buey, R.M.,Peterson, J.R.,Kollman, J.M.; IMPDH1 retinal variants control filament architecture to tune allosteric regulation.; Nat.Struct.Mol.Biol., 29:47-58, 2022; PubMed: 35013599; DOI: 10.1038/s41594-021-00706-2

Experimental method

ELECTRON MICROSCOPY (2.8 Å)