6EPC
| Ground state 26S proteasome (GS2) | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | 登録日 | 2017-10-11 | 公開日 | 2018-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (12.3 Å) | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
|
|
6EPD
| Substrate processing state 26S proteasome (SPS1) | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | 登録日 | 2017-10-11 | 公開日 | 2018-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (15.4 Å) | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
|
|
6EPF
| Ground state 26S proteasome (GS1) | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | 登録日 | 2017-10-11 | 公開日 | 2018-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (11.8 Å) | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
|
|
6EPE
| Substrate processing state 26S proteasome (SPS2) | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | 登録日 | 2017-10-11 | 公開日 | 2018-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (12.8 Å) | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
|
|
6EZ8
| Human Huntingtin-HAP40 complex structure | 分子名称: | Factor VIII intron 22 protein, Huntingtin | 著者 | Guo, Q, Bin, H, Cheng, J, Pfeifer, G, Baumeister, W, Fernandez-Busnadiego, R, Kochanek, S. | 登録日 | 2017-11-14 | 公開日 | 2018-02-21 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | The cryo-electron microscopy structure of huntingtin. Nature, 555, 2018
|
|
5DNA
| Crystal structure of Candida boidinii formate dehydrogenase | 分子名称: | FORMATE DEHYDROGENASE, SULFATE ION | 著者 | Guo, Q, Gakhar, L, Wichersham, K, Francis, K, Vardi-Kilshtain, A, Major, D.T, Cheatum, C.M, Kohen, A. | 登録日 | 2015-09-09 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii. Biochemistry, 55, 2016
|
|
5DN9
| Crystal structure of Candida boidinii formate dehydrogenase complexed with NAD+ and azide | 分子名称: | AZIDE ION, CHLORIDE ION, FDH, ... | 著者 | Guo, Q, Gakhar, L, Wichersham, K, Francis, K, Vardi-Kilshtain, A, Major, D.T, Cheatum, C.M, Kohen, A. | 登録日 | 2015-09-09 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii. Biochemistry, 55, 2016
|
|
5YBJ
| Structure of apo KANK1 ankyrin domain | 分子名称: | GLYCEROL, KN motif and ankyrin repeat domain-containing protein 1 | 著者 | Guo, Q, Liao, S, Min, J, Xu, C, Structural Genomics Consortium (SGC) | 登録日 | 2017-09-05 | 公開日 | 2017-12-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.341 Å) | 主引用文献 | Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins. J. Biol. Chem., 293, 2018
|
|
5YBV
| The structure of the KANK2 ankyrin domain with the KIF21A peptide | 分子名称: | GLYCEROL, KN motif and ankyrin repeat domain-containing protein 2, Kinesin-like protein KIF21A, ... | 著者 | Guo, Q, Liao, S, Min, J, Xu, C, Structural Genomics Consortium (SGC) | 登録日 | 2017-09-05 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins. J. Biol. Chem., 293, 2018
|
|
5YBU
| Structure of the KANK1 ankyrin domain in complex with KIF21A peptide | 分子名称: | KN motif and ankyrin repeat domain-containing protein 1, Kinesin-like protein KIF21A | 著者 | Guo, Q, Liao, S, Min, J, Xu, C, Structural Genomics Consortium (SGC) | 登録日 | 2017-09-05 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins. J. Biol. Chem., 293, 2018
|
|
6K0X
| |
7XDT
| |
7XGR
| |
2X6L
| |
2X69
| |
2X6G
| |
2YPU
| human insulin degrading enzyme E111Q in complex with inhibitor compound 41367 | 分子名称: | 2-[[2-[[(2S)-3-(3H-IMIDAZOL-4-YL)-1-METHOXY-1-OXO-PROPAN-2-YL]AMINO]-2-OXO-ETHYL]-(PHENYLMETHYL)AMINO]ETHANOIC ACID, INSULIN-DEGRADING ENZYME, ZINC ION | 著者 | Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.-J. | 登録日 | 2012-11-01 | 公開日 | 2012-11-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Imidazole-Derived 2-[N-Carbamoylmethyl-Alkylamino]Acetic Acids,Substrate-Dependent Modulators of Insulin-Degrading Enzyme in Amyloid-Beta Hydrolysis Eur J Med Chem, 79C, 2014
|
|
8JMT
| Structure of the adhesion GPCR ADGRL3 in the apo state | 分子名称: | Adhesion G protein-coupled receptor L3,Soluble cytochrome b562 | 著者 | Tao, Y, Guo, Q, He, B, Zhong, Y. | 登録日 | 2023-06-05 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
|
|
8JJO
| Cryo-EM structure of the beta2AR-mBRIL/1b3 Fab/Glue complex with an antagonist | 分子名称: | (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, Beta-2 adrenergic receptor,Beta-2 adrenergic receptor,Soluble cytochrome b562 | 著者 | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | 登録日 | 2023-05-31 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
|
|
8J7E
| |
8JJL
| cryo-EM structure of the beta2-AR-mBRIL/1b3 Fab/Glue complex with a full agonist | 分子名称: | Beta-2 adrenergic receptor,Soluble cytochrome b562, Olodaterol | 著者 | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | 登録日 | 2023-05-30 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
|
|
8JJ8
| Cryo-EM structure of the beta2AR-mBRIL/1b3 Fab/Glue complex with a partial agonist | 分子名称: | Beta-2 adrenergic receptor,Soluble cytochrome b562, ~{N}-[5-[(1~{R})-2-[[(2~{R})-1-(4-methoxyphenyl)propan-2-yl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide | 著者 | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | 登録日 | 2023-05-29 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
|
|
4DWK
| Structure of cystein free insulin degrading enzyme with compound bdm41671 ((s)-2-{2-[carboxymethyl-(3-phenyl-propyl)-amino]-acetylamino}-3-(1h-imidazol-4-yl)-propionic acid methyl ester) | 分子名称: | Insulin-degrading enzyme, ZINC ION, methyl N-(carboxymethyl)-N-(3-phenylpropyl)glycyl-L-histidinate | 著者 | Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J. | 登録日 | 2012-02-24 | 公開日 | 2013-04-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis. Eur.J.Med.Chem., 79, 2014
|
|
4DTT
| Crystal structure of human insulin degrading enzyme (ide) in complex with compund 41367 | 分子名称: | 2-[[2-[[(2S)-3-(3H-IMIDAZOL-4-YL)-1-METHOXY-1-OXO-PROPAN-2-YL]AMINO]-2-OXO-ETHYL]-(PHENYLMETHYL)AMINO]ETHANOIC ACID, Insulin-degrading enzyme, ZINC ION | 著者 | Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J. | 登録日 | 2012-02-21 | 公開日 | 2013-02-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis. Eur.J.Med.Chem., 79, 2014
|
|
3QZ2
| |