8IAK
 
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8IAM
 | | Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3D) complex | | 分子名称: | Chimera of Long chain base biosynthesis protein 1 and Serine palmitoyltransferase 1, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Xie, T, Gong, X. | | 登録日 | 2023-02-08 | | 公開日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide.
Cell Rep, 43, 2024
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8IAJ
 | | Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3A) complex | | 分子名称: | N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, PYRIDOXAL-5'-PHOSPHATE, Protein ORM2, ... | | 著者 | Xie, T, Gong, X. | | 登録日 | 2023-02-08 | | 公開日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide.
Cell Rep, 43, 2024
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4O6Y
 | | Crystal Structure of Cytochrome b561 | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Probable transmembrane ascorbate ferrireductase 2, SULFATE ION | | 著者 | Lu, P, Ma, D, Yan, C, Gong, X, Du, M, Shi, Y. | | 登録日 | 2013-12-24 | | 公開日 | 2014-02-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
Proc.Natl.Acad.Sci.USA, 111, 2014
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4O7G
 | | Crystal Structure of Ascorbate-bound Cytochrome b561, crystal soaked in 1 M L-ascorbate for 40 minutes | | 分子名称: | ASCORBIC ACID, PROTOPORPHYRIN IX CONTAINING FE, Probable transmembrane ascorbate ferrireductase 2, ... | | 著者 | Lu, P, Ma, D, Yan, C, Gong, X, Du, M, Shi, Y. | | 登録日 | 2013-12-24 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.211 Å) | | 主引用文献 | Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
Proc.Natl.Acad.Sci.USA, 111, 2014
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4O79
 | | Crystal Structure of Ascorbate-bound Cytochrome b561, crystal soaked in 1 M L-ascorbate for 10 minutes | | 分子名称: | ASCORBIC ACID, PROTOPORPHYRIN IX CONTAINING FE, Probable transmembrane ascorbate ferrireductase 2, ... | | 著者 | Lu, P, Ma, D, Yan, C, Gong, X, Du, M, Shi, Y. | | 登録日 | 2013-12-24 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | | 主引用文献 | Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
Proc.Natl.Acad.Sci.USA, 111, 2014
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8IZD
 | | Cryo-EM structure of the C26-CoA-bound Lac1-Lip1 complex | | 分子名称: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Ceramide synthase LAC1, Ceramide synthase subunit LIP1, ... | | 著者 | Xie, T, Fang, Q, Gong, X. | | 登録日 | 2023-04-07 | | 公開日 | 2023-12-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structure and mechanism of a eukaryotic ceramide synthase complex.
Embo J., 42, 2023
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8IZF
 | | Cryo-EM structure of the Lac1-Lip1 (Lip1-S74F) complex | | 分子名称: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Ceramide synthase LAC1, Ceramide synthase subunit LIP1 | | 著者 | Xie, T, Fang, Q, Gong, X. | | 登録日 | 2023-04-07 | | 公開日 | 2023-12-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Structure and mechanism of a eukaryotic ceramide synthase complex.
Embo J., 42, 2023
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5XJY
 | | Cryo-EM structure of human ABCA1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette sub-family A member 1, ... | | 著者 | Qian, H.W, Yan, N, Gong, X. | | 登録日 | 2017-05-04 | | 公開日 | 2017-06-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structure of the Human Lipid Exporter ABCA1.
Cell, 169, 2017
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4IU8
 | | Crystal structure of a membrane transporter (selenomethionine derivative) | | 分子名称: | NITRATE ION, Nitrite extrusion protein 2 | | 著者 | Yan, H, Huang, W, Yan, C, Gong, X, Jiang, S, Zhao, Y, Wang, J, Shi, Y. | | 登録日 | 2013-01-20 | | 公開日 | 2013-04-17 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structure and mechanism of a nitrate transporter.
Cell Rep, 3, 2013
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4IU9
 | | Crystal structure of a membrane transporter | | 分子名称: | Nitrite extrusion protein 2 | | 著者 | Yan, H, Huang, W, Yan, C, Gong, X, Jiang, S, Zhao, Y, Wang, J, Shi, Y. | | 登録日 | 2013-01-20 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | | 主引用文献 | Structure and mechanism of a nitrate transporter.
Cell Rep, 3, 2013
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7YIU
 | | Cryo-EM structure of the C6-ceramide-bound SPT-ORMDL3 complex | | 分子名称: | HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)HEXANAMIDE, ORM1-like protein 3, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-18 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Nat Commun, 14, 2023
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7YJ2
 | | Cryo-EM structure of SPT-ORMDL3 (ORMDL3-N13A) complex | | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-19 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Nat Commun, 14, 2023
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7YJ1
 | | Cryo-EM structure of SPT-ORMDL3 (ORMDL3-deltaN2) complex | | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-19 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Nat Commun, 14, 2023
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7YIY
 | | Cryo-EM structure of SPT-ORMDL3 complex | | 分子名称: | N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-18 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Nat Commun, 14, 2023
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7YJK
 | | Cryo-EM structure of the dimeric atSPT-ORM1 complex | | 分子名称: | Long chain base biosynthesis protein 1, Long chain base biosynthesis protein 2a, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-20 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023
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7YJN
 | | Cryo-EM structure of the monomeric atSPT-ORM1 (ORM1-N17A) complex | | 分子名称: | Long chain base biosynthesis protein 1, Long chain base biosynthesis protein 2a, ORMDL family protein, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-20 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023
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7YJO
 | | Cryo-EM structure of the monomeric atSPT-ORM1 (LCB2a-deltaN5) complex | | 分子名称: | Long chain base biosynthesis protein 2a, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ORMDL family protein, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-20 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023
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7YJM
 | | Cryo-EM structure of the monomeric atSPT-ORM1 complex | | 分子名称: | Long chain base biosynthesis protein 2a, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ORMDL family protein, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-20 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023
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5XTA
 | | Crystal structure of lpg1832, a VirK family protein from Legionella pneumophila | | 分子名称: | GLYCEROL, SULFATE ION, VirK protein | | 著者 | Yin, S, Gong, X, Zhang, N, Ge, H. | | 登録日 | 2017-06-18 | | 公開日 | 2017-08-16 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of lpg1832, a VirK family protein from Legionella pneumophila, reveals a novel fold for bacterial VirK proteins
FEBS Lett., 591, 2017
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7W02
 | | Cryo-EM structure of ATP-bound ABCA3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Xie, T, Zhang, Z.K, Yue, J, Gong, X. | | 登録日 | 2021-11-17 | | 公開日 | 2022-04-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of the human surfactant lipid transporter ABCA3.
Sci Adv, 8, 2022
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7W01
 | | Cryo-EM structure of nucleotide-free ABCA3 | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Xie, T, Zhang, Z.K, Yue, J, Gong, X. | | 登録日 | 2021-11-17 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of the human surfactant lipid transporter ABCA3.
Sci Adv, 8, 2022
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7E7Q
 | | Cryo-EM structure of human ABCA4 in ATP-bound state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Xie, T, Zhang, Z.K, Gong, X. | | 登録日 | 2021-02-26 | | 公開日 | 2021-06-30 | | 最終更新日 | 2021-07-07 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of substrate recognition and translocation by human ABCA4.
Nat Commun, 12, 2021
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7E7O
 | | Cryo-EM structure of human ABCA4 in NRPE-bound state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ... | | 著者 | Xie, T, Zhang, Z.K, Gong, X. | | 登録日 | 2021-02-26 | | 公開日 | 2021-06-30 | | 最終更新日 | 2021-07-07 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of substrate recognition and translocation by human ABCA4.
Nat Commun, 12, 2021
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7E7I
 | | Cryo-EM structure of human ABCA4 in the apo state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ... | | 著者 | Xie, T, Zhang, Z.K, Gong, X. | | 登録日 | 2021-02-26 | | 公開日 | 2021-06-30 | | 最終更新日 | 2021-07-07 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of substrate recognition and translocation by human ABCA4.
Nat Commun, 12, 2021
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