7CQI

Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex

Summary for 7CQI

• Entry DOI: 10.2210/pdb7cqi/pdb
• EMDB information: 30080 30441
• Descriptor: Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ORM1-like protein 3, ... (6 entities in total)
• Functional Keywords: membrane protein, lipid synthesis, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 198228.91

Authors

Li, S.S.,Xie, T.,Wang, L.,Gong, X. (deposition date: 2020-08-11, release date: 2021-02-10, Last modification date: 2024-03-27)

• Primary citation: Li, S.,Xie, T.,Liu, P.,Wang, L.,Gong, X.; Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.; Nat.Struct.Mol.Biol., 28:249-257, 2021; PubMed: 33558762; DOI: 10.1038/s41594-020-00553-7

Experimental method

ELECTRON MICROSCOPY (3.2 Å)