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8SP0
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BU of 8sp0 by Molmil
Symmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid
分子名称: MAGNESIUM ION, TIR-APAZ, guide RNA, ...
著者Shen, Z.F, Yang, X.Y, Fu, T.M.
登録日2023-05-01
公開日2023-08-23
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
8EE7
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BU of 8ee7 by Molmil
Structure of focused PtuA(dimer) and PtuB(monomer) complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, PtuA, PtuB
著者Shen, Z.F, Fu, T.M.
登録日2022-09-06
公開日2024-01-03
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Nat.Struct.Mol.Biol., 31, 2024
8EEA
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BU of 8eea by Molmil
Structure of E.coli Septu (PtuAB) complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, PtuA, PtuB
著者Shen, Z.F, Fu, T.M.
登録日2022-09-06
公開日2023-12-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Nat.Struct.Mol.Biol., 31, 2024
8EE4
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BU of 8ee4 by Molmil
Structure of PtuA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, PtuA
著者Shen, Z.F, Fu, T.M.
登録日2022-09-06
公開日2024-01-03
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Nat.Struct.Mol.Biol., 31, 2024
8SQU
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BU of 8squ by Molmil
Monomeric MapSPARTA bound with guide RNA and target DNA hybrid
分子名称: MAGNESIUM ION, TIR-APAZ, guide RNA, ...
著者Shen, Z.F, Yang, X.Y, Fu, T.M.
登録日2023-05-04
公開日2023-08-23
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
8UAE
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BU of 8uae by Molmil
E. coli Sir2_HerA complex (12:6) with ATPgamaS
分子名称: MAGNESIUM ION, Nucleoside triphosphate hydrolase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Shen, Z.F, Lin, Q.P, Fu, T.M.
登録日2023-09-20
公開日2023-12-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
8UAF
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BU of 8uaf by Molmil
E. coli Sir2_HerA complex (12:6) bound with NAD+
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Shen, Z.F, Lin, Q.P, Fu, T.M.
登録日2023-09-20
公開日2023-12-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
8EFY
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BU of 8efy by Molmil
Structure of double homo-hexameric AAA+ ATPase RuvB motors
分子名称: ADENOSINE-5'-DIPHOSPHATE, Holliday junction ATP-dependent DNA helicase RuvB, MAGNESIUM ION, ...
著者Shen, Z.F, Rish, A.D, Fu, T.M.
登録日2022-09-10
公開日2023-05-10
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structure of double homo-hexameric AAA+ ATPase RuvB motor binding with DNA substrate
To Be Published
8EFV
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BU of 8efv by Molmil
Structure of single homo-hexameric Holliday junction ATP-dependent DNA helicase RuvB motor
分子名称: 49-mer DNA, 51-mer DNA, ADENOSINE-5'-DIPHOSPHATE, ...
著者Shen, Z.F, Rish, A.D, Fu, T.M.
登録日2022-09-09
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure of single homo-hexameric Holliday junction ATP-dependent DNA helicase RuvB motor
To Be Published
8TJY
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BU of 8tjy by Molmil
Structure of Gabija AB complex
分子名称: Endonuclease GajA, Gabija protein GajB
著者Shen, Z.F, Yang, X.Y, Fu, T.M.
登録日2023-07-24
公開日2024-04-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Molecular basis of Gabija anti-phage supramolecular assemblies.
Nat.Struct.Mol.Biol., 2024
8SXX
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BU of 8sxx by Molmil
E. coli dodecamer SIR2
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein
著者Shen, Z.F, Lin, Q.P, Fu, T.M.
登録日2023-05-24
公開日2023-12-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
8SUB
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BU of 8sub by Molmil
E. coli SIR2-HerA complex (dodecamer SIR2 pentamer HerA)
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside triphosphate hydrolase, ...
著者Shen, Z.F, Lin, Q.P, Fu, T.M.
登録日2023-05-11
公開日2023-12-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
8SUX
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BU of 8sux by Molmil
Structure of E. coli PtuA hexamer
分子名称: ADENOSINE-5'-TRIPHOSPHATE, PtuA
著者Shen, Z.F, Yang, X.Y, Fu, T.M.
登録日2023-05-13
公開日2024-01-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Nat.Struct.Mol.Biol., 31, 2024
8FEX
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BU of 8fex by Molmil
Inactivate state of Maribacter polysiphoniae Argonuate (short pAgo system)
分子名称: TIR-APAZ, short pAgo
著者Shen, Z.F, Yang, X.Y, Fu, T.M.
登録日2022-12-06
公開日2023-08-23
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
8TK0
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BU of 8tk0 by Molmil
Structure of Gabija AB complex
分子名称: Endonuclease GajA
著者Shen, Z.F, Yang, X.Y, Fu, T.M.
登録日2023-07-24
公開日2024-04-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Molecular basis of Gabija anti-phage supramolecular assemblies.
Nat.Struct.Mol.Biol., 2024
8TK1
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BU of 8tk1 by Molmil
Structure of Gabija AB complex 1
分子名称: Endonuclease GajA, Gabija protein GajB
著者Shen, Z.F, Yang, X.Y, Fu, T.M.
登録日2023-07-25
公開日2024-04-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Molecular basis of Gabija anti-phage supramolecular assemblies.
Nat.Struct.Mol.Biol., 2024
7LF6
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BU of 7lf6 by Molmil
Structure of lysosomal membrane protein
分子名称: Endosomal/lysosomal potassium channel TMEM175
著者Shen, C, Fu, T.M, Wang, L.F, Rawson, S, Wu, H.
登録日2021-01-15
公開日2022-01-26
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献pH regulates potassium conductance and drives a constitutive proton current in human TMEM175.
Sci Adv, 8, 2022
7U4T
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BU of 7u4t by Molmil
Human V-ATPase in state 2 with SidK and mEAK-7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MTOR-associated protein MEAK7, ...
著者Wang, L, Fu, T.M.
登録日2022-03-01
公開日2022-08-24
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Identification of mEAK-7 as a human V-ATPase regulator via cryo-EM data mining.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EHX
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BU of 8ehx by Molmil
cryo-EM structure of TMEM63B in LMNG
分子名称: CSC1-like protein 2
著者Zheng, W, Fu, T.M, Holt, J.R.
登録日2022-09-14
公開日2023-08-23
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels.
Neuron, 111, 2023
8EHW
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BU of 8ehw by Molmil
cryo-EM structure of TMEM63A in nanodisc
分子名称: CSC1-like protein 1
著者Zheng, W, Fu, T.M, Holt, J.R.
登録日2022-09-14
公開日2023-08-23
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels.
Neuron, 111, 2023
6MJ2
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BU of 6mj2 by Molmil
Human TRPM2 ion channel in a calcium- and ADPR-bound state
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 2
著者Wang, L, Fu, T.M, Xia, S, Wu, H.
登録日2018-09-20
公開日2018-12-12
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (6.36 Å)
主引用文献Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6MIX
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BU of 6mix by Molmil
Human TRPM2 ion channel in apo state
分子名称: Transient receptor potential cation channel subfamily M member 2
著者Wang, L, Fu, T.M, Xia, S, Wu, H.
登録日2018-09-20
公開日2018-12-12
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6MIZ
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BU of 6miz by Molmil
Human TRPM2 ion channel in an ADPR-bound state
分子名称: Transient receptor potential cation channel subfamily M member 2
著者Wang, L, Fu, T.M, Xia, S, Wu, H.
登録日2018-09-20
公開日2018-12-12
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6NDJ
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BU of 6ndj by Molmil
Crystal structure of human NLRP6 PYD domain with MBP fusion
分子名称: Maltose/maltodextrin-binding periplasmic protein, NACHT, LRR and PYD domains-containing protein 6 chimera
著者Shen, C, Fu, T.M, Wu, H.
登録日2018-12-13
公開日2019-01-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Molecular mechanism for NLRP6 inflammasome assembly and activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6NCV
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BU of 6ncv by Molmil
Cryo-EM structure of NLRP6 PYD filament
分子名称: NACHT, LRR and PYD domains-containing protein 6
著者Shen, C, Fu, T.M, Wu, H.
登録日2018-12-12
公開日2019-01-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular mechanism for NLRP6 inflammasome assembly and activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019

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