8CBW
| CryoEM structure of the Hendra henipavirus nucleocapsid sauronoid assembly monomer | 分子名称: | Nucleocapsid, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3') | 著者 | Passchier, T.C, Maskell, D.P, Edwards, T.A, Barr, J.N. | 登録日 | 2023-01-26 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.485 Å) | 主引用文献 | The cryoEM structure of the Hendra henipavirus nucleoprotein reveals insights into paramyxoviral nucleocapsid architectures. Sci Rep, 14, 2024
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8C4H
| CryoEM structure of the Hendra henipavirus nucleocapsid sauronoid assembly multimer | 分子名称: | Nucleocapsid, RNA (84-MER) | 著者 | Passchier, T.C, Maskell, D.P, Edwards, T.A, Barr, J.N. | 登録日 | 2023-01-04 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.485 Å) | 主引用文献 | The cryoEM structure of the Hendra henipavirus nucleoprotein reveals insights into paramyxoviral nucleocapsid architectures. Sci Rep, 14, 2024
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6YS5
| Acinetobacter baumannii ribosome-amikacin complex - 30S subunit head | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S13, ... | 著者 | Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A. | 登録日 | 2020-04-21 | 公開日 | 2020-09-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics. Structure, 28, 2020
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6YTF
| Acinetobacter baumannii ribosome-tigecycline complex - 30S subunit head | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S13, ... | 著者 | Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A. | 登録日 | 2020-04-24 | 公開日 | 2020-09-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics. Structure, 28, 2020
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6YWZ
| Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid | 分子名称: | 2-[(~{E})-(4-oxidanylidenebutanoylhydrazinylidene)methyl]benzoic acid, ARGININE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Hegedus, Z, Hobor, F, Shoemark, D.K, Celis, S, Lian, L.J, Trinh, C.H, Sessions, R.B, Edwards, T.A, Wilson, A.J. | 登録日 | 2020-04-30 | 公開日 | 2021-01-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Identification of beta-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation. Chem Sci, 12, 2021
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6YX1
| Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid | 分子名称: | 2-[[2-(5-oxidanylidenepentanoyl)hydrazinyl]methyl]benzoic acid, ARGININE, LEUCINE, ... | 著者 | Hegedus, Z, Hobor, F, Shoemark, D.K, Celis, S, Lian, L.J, Trinh, C.H, Sessions, R.B, Edwards, T.A, Wilson, A.J. | 登録日 | 2020-04-30 | 公開日 | 2021-01-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identification of beta-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation. Chem Sci, 12, 2021
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6YT9
| Acinetobacter baumannii ribosome-tigecycline complex - 30S subunit body | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A. | 登録日 | 2020-04-24 | 公開日 | 2020-09-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics. Structure, 28, 2020
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6YSI
| Acinetobacter baumannii ribosome-tigecycline complex - 50S subunit | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A. | 登録日 | 2020-04-22 | 公開日 | 2020-09-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics. Structure, 28, 2020
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7A00
| Crystal structure of Shank1 PDZ in complex with L6F mutant of the C-terminal hexapeptide from GKAP | 分子名称: | L6F mutant of C-terminal hexapeptide from Guanylate kinase-associated protein, SH3 and multiple ankyrin repeat domains protein 1 | 著者 | Zsofia, H, Hetherington, K, Fruzsina, H, Edwards, T.A, Wilson, A.J. | 登録日 | 2020-08-05 | 公開日 | 2021-07-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Query-guided protein-protein interaction inhibitor discovery. Chem Sci, 12, 2021
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6Z0O
| Structure of Affimer-NP bound to Crimean-Congo Haemorrhagic Fever Virus Nucleocapsid Protein | 分子名称: | Affimer-NP, Nucleocapsid | 著者 | Alvarez-Rodriguez, B, Tiede, C, Trinh, C, Tomlinson, D, Edwards, T.A, Barr, J.N. | 登録日 | 2020-05-10 | 公開日 | 2020-05-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5974 Å) | 主引用文献 | Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests. Plos Negl Trop Dis, 14, 2020
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6YX2
| Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid | 分子名称: | 4-[[(~{E})-5-oxidanylidenepentanoyldiazenyl]methyl]benzoic acid, PWW-THR-ARG-LEU, SH3 and multiple ankyrin repeat domains protein 1 | 著者 | Hegedus, Z, Hobor, F, Shoemark, D.K, Celis, S, Lian, L.J, Trinh, C.H, Sessions, R.B, Edwards, T.A, Wilson, A.J. | 登録日 | 2020-04-30 | 公開日 | 2021-01-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Identification of beta-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation. Chem Sci, 12, 2021
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6YX0
| Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid | 分子名称: | 4-[[2-(4-oxidanylidenebutanoyl)hydrazinyl]methyl]benzoic acid, PWQ-THR-ARG-LEU, SH3 and multiple ankyrin repeat domains protein 1 | 著者 | Hegedus, Z, Hobor, F, Shoemark, D.K, Celis, S, Trinh, C.H, Sessions, R.B, Edwards, T.A, Wilson, A.J. | 登録日 | 2020-04-30 | 公開日 | 2021-01-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Identification of beta-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation. Chem Sci, 12, 2021
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7NY8
| Affimer K69 - KRAS protein complex | 分子名称: | Affimer K69, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Turner, A.L, Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C. | 登録日 | 2021-03-21 | 公開日 | 2021-07-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site. Nat Commun, 12, 2021
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5A37
| Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. | 分子名称: | HUMAN ALPHA-ACTININ-2 | 著者 | Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. | 登録日 | 2015-05-27 | 公開日 | 2016-06-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation. Biochem.J., 473, 2016
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5A36
| Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. | 分子名称: | ALPHA-ACTININ-2 | 著者 | Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. | 登録日 | 2015-05-27 | 公開日 | 2016-06-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation. Biochem.J., 473, 2016
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5A97
| Hazara virus nucleocapsid protain | 分子名称: | NUCLEOCAPSID PROTEIN | 著者 | Surtees, R, Ariza, A, Hewson, R, Barr, J.N, Edwards, T.A. | 登録日 | 2015-07-17 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The Crystal Structure of the Hazara Virus Nucleocapsid Protein. Bmc Struct.Biol., 15, 2015
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5A4B
| Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. | 分子名称: | HUMAN ALPHA-ACTININ-2 | 著者 | Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. | 登録日 | 2015-06-05 | 公開日 | 2016-06-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation. Biochem.J., 473, 2016
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5A38
| Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. | 分子名称: | ALPHA-ACTININ-2 | 著者 | Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. | 登録日 | 2015-05-27 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation. Biochem.J., 473, 2016
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5C3F
| Crystal structure of Mcl-1 bound to BID-MM | 分子名称: | BID-MM, GLYCEROL, Induced myeloid leukemia cell differentiation protein Mcl-1 | 著者 | Miles, J.A, Yeo, D.J, Rowell, P, Rodriguez-Marin, S, Pask, C.M, Warriner, S.L, Edwards, T.A, Wilson, A.J. | 登録日 | 2015-06-17 | 公開日 | 2016-04-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Hydrocarbon constrained peptides - understanding preorganisation and binding affinity. Chem Sci, 7, 2016
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5C3G
| Crystal structure of Bcl-xl bound to BIM-MM | 分子名称: | Bcl-2-like protein 1,Bcl-2-like protein 1, Bcl-2-like protein 11 | 著者 | Miles, J.A, Yeo, D.J, Rowell, P, Rodriguez-Marin, S, Pask, C.M, Warriner, S.L, Edwards, T.A, Wilson, A.J. | 登録日 | 2015-06-17 | 公開日 | 2016-04-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Hydrocarbon constrained peptides - understanding preorganisation and binding affinity. Chem Sci, 7, 2016
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5A0O
| adhiron raised against p300 | 分子名称: | ADHIRON | 著者 | Kyle, H.F, Wickson, K.F, Stott, J, Burslem, G.M, Breeze, A.L, Tiede, C, Tomlinson, D.C, Warriner, S.L, Nelson, A, Wilson, A.J, Edwards, T.A. | 登録日 | 2015-04-21 | 公開日 | 2015-07-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Exploration of the Hif-1Alpha.P300 Interface Using Peptide and Adhiron Phage Display Technologies Mol.Biosyst., 11, 2015
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2XS2
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2YB5
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2Y8E
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2XS7
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