6Z0O

Structure of Affimer-NP bound to Crimean-Congo Haemorrhagic Fever Virus Nucleocapsid Protein

Summary for 6Z0O

Entry DOI	10.2210/pdb6z0o/pdb
Related	4AKL
Descriptor	Nucleocapsid, Affimer-NP (3 entities in total)
Functional Keywords	crimean-congo hemorrhagic fever virus nucleoprotein, affimer-np, complex, high-affinity, anti-viral, rna-binding, viral protein
Biological source	Crimean-Congo hemorrhagic fever orthonairovirus More
Total number of polymer chains	4
Total formula weight	129805.86
Authors	Alvarez-Rodriguez, B.,Tiede, C.,Trinh, C.,Tomlinson, D.,Edwards, T.A.,Barr, J.N. (deposition date: 2020-05-10, release date: 2020-05-27, Last modification date: 2024-01-24)
Primary citation	Alvarez-Rodriguez, B.,Tiede, C.,Hoste, A.C.R.,Surtees, R.A.,Trinh, C.H.,Slack, G.S.,Chamberlain, J.,Hewson, R.,Fresco, A.,Sastre, P.,Tomlinson, D.C.,Millner, P.A.,Edwards, T.A.,Barr, J.N. Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests. Plos Negl Trop Dis, 14:e0008364-e0008364, 2020 Cited by PubMed: 32492018 DOI: 10.1371/journal.pntd.0008364 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5974 Å)

Structure validation