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7ZPA
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Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C1 symmetry
分子名称: DNA (48-MER), PLP-dependent aminotransferase family protein
著者Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M.
登録日2022-04-27
公開日2023-07-05
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
7PQ9
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Crystal structure of Bacillus clausii pdxR at 2.8 Angstroms resolution
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Vivoli Vega, M, Isupov, M.N, Harmer, N.
登録日2021-09-16
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
2YXT
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BU of 2yxt by Molmil
Human Pyridoxal Kinase
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Pyridoxal kinase, ...
著者Safo, M.K, Musayev, F.N, Ko, T.P, Schirch, V.
登録日2007-04-27
公開日2008-03-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation.
Protein Sci., 16, 2007
2YXU
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BU of 2yxu by Molmil
Human Pyridoxal Kinase
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Safo, M.K, Musayev, F.N, Ko, T.P, Schirch, V.
登録日2007-04-27
公開日2008-03-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation.
Protein Sci., 16, 2007
6YLZ
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BU of 6ylz by Molmil
X-ray structure of the K72I,Y129F,R133L, H199A quadruple mutant of PNP-oxidase from E. coli
分子名称: FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, Pyridoxine/pyridoxamine 5'-phosphate oxidase, ...
著者Battista, T, Sularea, M, Barile, A, Fiorillo, A, Tramonti, A, Ilari, A.
登録日2020-04-07
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.558 Å)
主引用文献Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase.
J.Biol.Chem., 296, 2021
6YMH
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BU of 6ymh by Molmil
X-ray structure of the K72I, Y129F, R133L, H199A quadruple mutant of PNP-oxidase from E. coli in complex with PLP
分子名称: FLAVIN MONONUCLEOTIDE, PYRIDOXAL-5'-PHOSPHATE, Pyridoxine/pyridoxamine 5'-phosphate oxidase, ...
著者Battista, T, Sularea, M, Barile, A, Fiorillo, A, Tramonti, A, Ilari, A.
登録日2020-04-08
公開日2021-04-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.417 Å)
主引用文献Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase.
J.Biol.Chem., 296, 2021
4PVF
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BU of 4pvf by Molmil
Crystal structure of Homo sapiens holo serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), isoform 3, transcript variant 5, 483 aa, at 2.6 ang. resolution
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Serine hydroxymethyltransferase, ...
著者Giardina, G, Brunotti, P, Fiascarelli, A, Contestabile, R, Cutruzzola, F.
登録日2014-03-17
公開日2015-01-28
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state.
Febs J., 282, 2015
4EOH
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BU of 4eoh by Molmil
Crystal Structure of Human PL Kinase with bound Theophylline
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Pyridoxal Kinase, SODIUM ION, ...
著者Safo, M.K, Gandhi, A.K, Musayev, F.N.
登録日2012-04-14
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition.
Plos One, 7, 2012
4EN4
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BU of 4en4 by Molmil
Crystal Structure of the Ternary Human PL Kinase-Ginkgotoxin-MgATP Complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(hydroxymethyl)-4-(methoxymethyl)-2-methylpyridin-3-ol, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Safo, M.K, Musayev, F.N, Gandhi, A.K.
登録日2012-04-12
公開日2012-05-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition.
Plos One, 7, 2012
7UAX
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The crystal structure of the K36A/K38A double mutant of E. coli YGGS in complex with PLP
分子名称: PHOSPHATE ION, Pyridoxal phosphate homeostasis protein
著者Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K.
登録日2022-03-14
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
7UAU
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BU of 7uau by Molmil
The crystal structure of the K137A mutant of E. coli YGGS in complex with PLP
分子名称: PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein, SULFATE ION
著者Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K.
登録日2022-03-14
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
7UBP
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BU of 7ubp by Molmil
The crystal structure of the K36A/K137A double mutant of E. coli YGGS in complex with PLP
分子名称: PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein, SULFATE ION
著者Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K.
登録日2022-03-15
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
7UAT
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BU of 7uat by Molmil
The crystal structure of the K36A mutant of E. coli YGGS in complex with PLP
分子名称: PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein
著者Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K.
登録日2022-03-14
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
7UB8
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BU of 7ub8 by Molmil
The crystal structure of the K38A/K137A/K233A/K234A quadruple mutant of E. coli YGGS in complex with PLP
分子名称: 1,4-BUTANEDIOL, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein
著者Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K.
登録日2022-03-14
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
7UBQ
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BU of 7ubq by Molmil
The crystal structure of the wild-type of E. coli YGGS in complex with PNP
分子名称: PYRIDOXINE-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein
著者Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K.
登録日2022-03-15
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
7UB4
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BU of 7ub4 by Molmil
The crystal structure of the K36A/K38A/K233A/K234A quadruple mutant of E. coli YGGS in complex with PLP
分子名称: PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein
著者Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K.
登録日2022-03-14
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
7U9C
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BU of 7u9c by Molmil
Crystal Structure of the wild type Escherichia coli Pyridoxal 5'-phosphate homeostasis protein (YGGS)
分子名称: PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein
著者Donkor, A.K, Ghatge, M.S, Safo, M.K, Musayev, F.N.
登録日2022-03-10
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
7U9H
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BU of 7u9h by Molmil
Crystal Structure of Escherichia coli apo Pyridoxal 5'-phosphate homeostasis protein (YGGS)
分子名称: Pyridoxal phosphate homeostasis protein, SULFATE ION
著者Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K.
登録日2022-03-10
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
3G8M
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Serine Hydroxymethyltransferase Y55F Mutant
分子名称: PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase
著者Angelucci, F, Ilari, A.
登録日2009-02-12
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Role of a conserved active site cation-pi interaction in Escherichia coli serine hydroxymethyltransferase.
Biochemistry, 48, 2009
8QYW
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Human Pyridoxine-5'-phosphate oxidase mutant R225H
分子名称: FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, Pyridoxine-5'-phosphate oxidase
著者Antonelli, L, Ilari, A, Fiorillo, A.
登録日2023-10-26
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.746 Å)
主引用文献Identification of the pyridoxal 5'-phosphate allosteric site in human pyridox(am)ine 5'-phosphate oxidase.
Protein Sci., 33, 2024
8QYT
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Human Pyridoxine-5'-phosphate oxidase in complex with PLP
分子名称: BETA-MERCAPTOETHANOL, FLAVIN MONONUCLEOTIDE, PYRIDOXAL-5'-PHOSPHATE, ...
著者Antonelli, L, Ilari, A, Fiorillo, A.
登録日2023-10-26
公開日2024-02-07
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Identification of the pyridoxal 5'-phosphate allosteric site in human pyridox(am)ine 5'-phosphate oxidase.
Protein Sci., 33, 2024
1QQW
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CRYSTAL STRUCTURE OF HUMAN ERYTHROCYTE CATALASE
分子名称: CATALASE, PROTOPORPHYRIN IX CONTAINING FE
著者Ko, T.P, Safo, M.K, Musayev, F.N, Wang, C, Wu, S.H, Abraham, D.J.
登録日1999-06-09
公開日1999-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of human erythrocyte catalase.
Acta Crystallogr.,Sect.D, 56, 2000
1F4J
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STRUCTURE OF TETRAGONAL CRYSTALS OF HUMAN ERYTHROCYTE CATALASE
分子名称: CATALASE, PROTOPORPHYRIN IX CONTAINING FE
著者Safo, M.K, Musayev, F.N, Wu, S.H, Abraham, D.J, Ko, T.P.
登録日2000-06-07
公開日2000-06-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of tetragonal crystals of human erythrocyte catalase.
Acta Crystallogr.,Sect.D, 57, 2001
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