8IJR
| The cryo-EM structure of human sphingomyelin synthase-related protein in complex with diacylglycerol/phosphoethanolamine | 分子名称: | (2S)-1-(hexadecanoyloxy)-3-hydroxypropan-2-yl (11Z)-octadec-11-enoate, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, Sphingomyelin synthase-related protein 1 | 著者 | Hu, K, Zhang, Q, Chen, Y, Yao, D, Zhou, L, Cao, Y. | 登録日 | 2023-02-28 | 公開日 | 2024-02-28 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis. Nat.Struct.Mol.Biol., 31, 2024
|
|
8IJQ
| The cryo-EM structure of human sphingomyelin synthase-related protein in complex with ceramide | 分子名称: | N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, Sphingomyelin synthase-related protein 1 | 著者 | Hu, K, Zhang, Q, Chen, Y, Yao, D, Zhou, L, Cao, Y. | 登録日 | 2023-02-27 | 公開日 | 2024-02-28 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis. Nat.Struct.Mol.Biol., 31, 2024
|
|
7VQK
| |
7Y53
| The cryo-EM structure of human ERAD retro-translocation complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Derlin-1, Transitional endoplasmic reticulum ATPase | 著者 | Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y. | 登録日 | 2022-06-16 | 公開日 | 2023-10-18 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | The cryo-EM structure of the human ERAD retrotranslocation complex. Sci Adv, 9, 2023
|
|
7Y59
| The cryo-EM structure of human ERAD retro-translocation complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Derlin-1, ... | 著者 | Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y. | 登録日 | 2022-06-16 | 公開日 | 2023-10-18 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (4.51 Å) | 主引用文献 | The cryo-EM structure of the human ERAD retrotranslocation complex. Sci Adv, 9, 2023
|
|
7Y4W
| The cryo-EM structure of human ERAD retro-translocation complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Derlin-1, Transitional endoplasmic reticulum ATPase | 著者 | Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y. | 登録日 | 2022-06-16 | 公開日 | 2023-10-18 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | The cryo-EM structure of the human ERAD retrotranslocation complex. Sci Adv, 9, 2023
|
|
6JYM
| |
6KIZ
| Cryo-EM structure of human MLL1-NCP complex, binding mode2 | 分子名称: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Huang, J, Xue, H, Yao, T. | 登録日 | 2019-07-20 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
|
|
6KIV
| Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom) | 分子名称: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Huang, J, Xue, H, Yao, T. | 登録日 | 2019-07-20 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
|
|
6KIU
| Cryo-EM structure of human MLL1-ubNCP complex (3.2 angstrom) | 分子名称: | DNA (145-MER), GLUTAMINE, Histone H2A, ... | 著者 | Huang, J, Xue, H, Yao, T. | 登録日 | 2019-07-20 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
|
|
6KIW
| Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom) | 分子名称: | DNA (144-MER), DNA (145-MER), Histone H2A, ... | 著者 | Huang, J, Xue, H, Yao, T. | 登録日 | 2019-07-20 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
|
|
6KI0
| Crystal Structure of Human ASC-CARD | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Xu, Z.H, Jin, T.C. | 登録日 | 2019-07-16 | 公開日 | 2020-07-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome. Cell Death Dis, 12, 2021
|
|
6KIX
| Cryo-EM structure of human MLL1-NCP complex, binding mode1 | 分子名称: | DNA (145-MER), GLUTAMINE, Histone H2A, ... | 著者 | Huang, J, Xue, H, Yao, T. | 登録日 | 2019-07-20 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
|
|
5Y36
| Cryo-EM structure of SpCas9-sgRNA-DNA ternary complex | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, complementary DNA strand, ... | 著者 | Huang, Q, Li, G, Huai, C. | 登録日 | 2017-07-27 | 公開日 | 2017-12-06 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | Structural insights into DNA cleavage activation of CRISPR-Cas9 system Nat Commun, 8, 2017
|
|
7C7A
| Cryo-EM structure of yeast Ribonuclease MRP with substrate ITS1 | 分子名称: | Internal Transcribed Spacer 1, MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, ... | 著者 | Lan, P, Wu, J, Lei, M. | 登録日 | 2020-05-24 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural insight into precursor ribosomal RNA processing by ribonuclease MRP. Science, 369, 2020
|
|
7C79
| Cryo-EM structure of yeast Ribonuclease MRP | 分子名称: | MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease MRP RNA subunit NME1, ... | 著者 | Lan, P, Wu, J, Lei, M. | 登録日 | 2020-05-24 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural insight into precursor ribosomal RNA processing by ribonuclease MRP. Science, 369, 2020
|
|
7D58
| cryo-EM structure of human RNA polymerase III in elongating state | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. | 登録日 | 2020-09-25 | 公開日 | 2021-02-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into transcriptional regulation of human RNA polymerase III. Nat.Struct.Mol.Biol., 28, 2021
|
|
7D59
| cryo-EM structure of human RNA polymerase III in apo state | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. | 登録日 | 2020-09-25 | 公開日 | 2021-02-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into transcriptional regulation of human RNA polymerase III. Nat.Struct.Mol.Biol., 28, 2021
|
|
7WTD
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, COENZYME A, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
|
|
7WTE
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2 | 分子名称: | ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
|
|
7WTA
| Cryo-EM structure of human pyruvate carboxylase in apo state | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
|
|
7WTC
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
|
|
7WTB
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
|
|
7EA8
| |
7EA5
| |