8IJQ
The cryo-EM structure of human sphingomyelin synthase-related protein in complex with ceramide
Summary for 8IJQ
Entry DOI | 10.2210/pdb8ijq/pdb |
EMDB information | 35492 |
Descriptor | Sphingomyelin synthase-related protein 1, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE (2 entities in total) |
Functional Keywords | synthase, sphingomyelin, cpe, membrane protein, lipid metabolism |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 189566.58 |
Authors | |
Primary citation | Hu, K.,Zhang, Q.,Chen, Y.,Yang, J.,Xia, Y.,Rao, B.,Li, S.,Shen, Y.,Cao, M.,Lu, H.,Qin, A.,Jiang, X.C.,Yao, D.,Zhao, J.,Zhou, L.,Cao, Y. Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38388831DOI: 10.1038/s41594-024-01237-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.45 Å) |
Structure validation
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