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1H4O
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BU of 1h4o by Molmil
Monoclinic form of human peroxiredoxin 5
分子名称: BENZOIC ACID, PEROXIREDOXIN 5
著者Declercq, J.P, Evrard, C.
登録日2001-05-11
公開日2001-10-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of Human Peroxiredoxin 5, a Novel Type of Mammalian Peroxiredoxin at 1.5 A Resolution
J.Mol.Biol., 311, 2001
4UZS
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BU of 4uzs by Molmil
Crystal structure of Bifidobacterium bifidum beta-galactosidase
分子名称: BETA-GALACTOSIDASE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Godoy, A.S, Murakami, M.T, Camilo, C.M, Bernardes, A, Polikarpov, I.
登録日2014-09-08
公開日2015-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal Structure of Beta1-6-Galactosidase from Bifidobacterium Bifidum S17: Trimeric Architecture, Molecular Determinants of the Enzymatic Activity and its Inhibition by Alpah-Galactose.
FEBS J., 283, 2016
6NOB
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BU of 6nob by Molmil
Structure of Glycoside Hydrolase family 32 from Bifidobacterium adolescentis
分子名称: 1,2-ETHANEDIOL, Beta-fructofuranosidase, DI(HYDROXYETHYL)ETHER
著者Mera, A.M, Lima, M.Z.T, Muniz, J.R.C.
登録日2019-01-16
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structure of GH32 from Bifidobacterium adolescentis
To Be Published
4XTA
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BU of 4xta by Molmil
MECHANISMS OF PPARgamma ACTIVATION BY NON-STEROIDAL ANTI-INFLAMMATORY DRUGS
分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, Peroxisome proliferator-activated receptor gamma
著者Puhl, A.C, Webb, P, Polikarpov, I.
登録日2015-01-23
公開日2015-11-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanisms of peroxisome proliferator activated receptor gamma regulation by non-steroidal anti-inflammatory drugs.
Nucl Recept Signal, 13, 2015
4XUH
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BU of 4xuh by Molmil
PPARgamma ligand binding domain in complex with sulindac sulfide
分子名称: 2-[(3Z)-6-fluoranyl-2-methyl-3-[(4-methylsulfanylphenyl)methylidene]inden-1-yl]ethanoic acid, Peroxisome proliferator-activated receptor gamma
著者Puhl, A.C, Polikaporv, I, Webb, P.
登録日2015-01-25
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Mechanisms of peroxisome proliferator activated receptor gamma regulation by non-steroidal anti-inflammatory drugs.
Nucl Recept Signal, 13, 2015
4XUM
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BU of 4xum by Molmil
PPARgamma ligand binding domain in complex with indomethacin
分子名称: INDOMETHACIN, Peroxisome proliferator-activated receptor gamma
著者Puhl, A.C, Webb, P, Polikarpov, I.
登録日2015-01-26
公開日2015-11-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanisms of peroxisome proliferator activated receptor gamma regulation by non-steroidal anti-inflammatory drugs.
Nucl Recept Signal, 13, 2015
4UCF
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BU of 4ucf by Molmil
Crystal structure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose
分子名称: BETA-GALACTOSIDASE, DI(HYDROXYETHYL)ETHER, N-PROPANOL, ...
著者Godoy, A.S, Murakami, M.T, Camilo, C.M, Bernardes, A, Polikarpov, I.
登録日2014-12-03
公開日2016-01-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal Structure of Beta1-6-Galactosidase from Bifidobacterium Bifidum S17: Trimeric Architecture, Molecular Determinants of the Enzymatic Activity and its Inhibition by Alpha-Galactose.
FEBS J., 283, 2016
6XQH
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BU of 6xqh by Molmil
Crystal structure of SCLam E144S mutant, a non-specific endo-beta-1,3(4)-glucanase from family GH16, co-crystallized with cellotriose, presenting a 1,3-beta-D-cellobiosyl-glucose and a cellobiose at active site
分子名称: CALCIUM ION, GH16 family protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, ...
著者Liberato, M.V, Squina, F.
登録日2020-07-09
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Insights into the dual cleavage activity of the GH16 laminarinase enzyme class on beta-1,3 and beta-1,4 glycosidic bonds.
J.Biol.Chem., 296, 2021
6XQM
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BU of 6xqm by Molmil
Crystal structure of SCLam E144S mutant, a non-specific endo-beta-1,3(4)-glucanase from family GH16, co-crystallized with laminarihexaose, presenting a laminaribiose and a glucose at active site
分子名称: CALCIUM ION, GH16 family protein, PHOSPHATE ION, ...
著者Liberato, M.V, Squina, F.
登録日2020-07-09
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Insights into the dual cleavage activity of the GH16 laminarinase enzyme class on beta-1,3 and beta-1,4 glycosidic bonds.
J.Biol.Chem., 296, 2021
6XQG
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BU of 6xqg by Molmil
Crystal structure of SCLam E144S mutant, a non-specific endo-beta-1,3(4)-glucanase from family GH16, co-crystallized with 1,3-beta-D-cellobiosyl-cellobiose, presenting a 1,3-beta-D-cellobiosyl-glucose at active site
分子名称: CALCIUM ION, GH16 family protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-alpha-D-glucopyranose
著者Liberato, M.V, Squina, F.
登録日2020-07-09
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Insights into the dual cleavage activity of the GH16 laminarinase enzyme class on beta-1,3 and beta-1,4 glycosidic bonds.
J.Biol.Chem., 296, 2021
6XQL
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BU of 6xql by Molmil
Crystal structure of SCLam E144S mutant, a non-specific endo-beta-1,3(4)-glucanase from family GH16, co-crystallized with cellohexaose, presenting a 1,3-beta-D-cellobiosyl-glucose at active site
分子名称: CALCIUM ION, GH16 family protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-alpha-D-glucopyranose
著者Liberato, M.V, Squina, F.
登録日2020-07-09
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Insights into the dual cleavage activity of the GH16 laminarinase enzyme class on beta-1,3 and beta-1,4 glycosidic bonds.
J.Biol.Chem., 296, 2021
6XQF
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BU of 6xqf by Molmil
Crystal structure of SCLam E144S mutant, a non-specific endo-beta-1,3(4)-glucanase from family GH16, co-crystallized with 1,3-beta-D-cellotriosyl-glucose, presenting a 1,3-beta-D-cellobiosyl-glucose at active site
分子名称: CALCIUM ION, GH16 family protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-alpha-D-glucopyranose
著者Liberato, M.V, Squina, F.
登録日2020-07-09
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Insights into the dual cleavage activity of the GH16 laminarinase enzyme class on beta-1,3 and beta-1,4 glycosidic bonds.
J.Biol.Chem., 296, 2021
2RC5
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BU of 2rc5 by Molmil
Refined structure of FNR from Leptospira interrogans
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin-NADP reductase, SULFATE ION, ...
著者Nascimento, A.S, Catalano-Dupuy, D.L, Polikarpov, I, Ceccarelli, E.A.
登録日2007-09-19
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.431 Å)
主引用文献Crystal structures of Leptospira interrogans FAD-containing ferredoxin-NADP+ reductase and its complex with NADP+.
Bmc Struct.Biol., 7, 2007
2RC6
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BU of 2rc6 by Molmil
Refined structure of FNR from Leptospira interrogans bound to NADP+
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin-NADP reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Nascimento, A.S, Catalano-Dupuy, D.L, Ceccarelli, E.A, Polikarpov, I.
登録日2007-09-19
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of Leptospira interrogans FAD-containing ferredoxin-NADP+ reductase and its complex with NADP+.
Bmc Struct.Biol., 7, 2007
4OJ4
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BU of 4oj4 by Molmil
Crystal structure of V290M PPARgamma mutant in complex with diclofenac
分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, CALCIUM ION, Peroxisome proliferator-activated receptor gamma
著者Puhl, A.C, Webb, P, Polikarpov, I.
登録日2014-01-20
公開日2015-02-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a PPAR ligand-resistance syndrome mutant
To be Published
3TKM
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BU of 3tkm by Molmil
Crystal structure PPAR delta binding GW0742
分子名称: GLYCEROL, Peroxisome proliferator-activated receptor delta, {4-[({2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid
著者Trivella, D.B.B, Batista, F.H, Polikarpov, I.
登録日2011-08-27
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.953 Å)
主引用文献Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding.
Plos One, 7, 2012
6ZZW
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BU of 6zzw by Molmil
Structure of the N terminal domain of Bc2L-C lectin (1-131) in complex with Globo H (H-type 3) and CAS No 912569-62-1
分子名称: Lectin, SODIUM ION, [3-(2-methylimidazol-1-yl)phenyl]methanamine, ...
著者Lal, K, Bermeo, R, Imberty, A, Varrot, A.
登録日2020-08-05
公開日2021-04-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Prediction and Validation of a Druggable Site on Virulence Factor of Drug Resistant Burkholderia cenocepacia*.
Chemistry, 27, 2021
7AH8
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BU of 7ah8 by Molmil
NF-Y bound to suramin inhibitor
分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, CITRATE ANION, GLYCEROL, ...
著者Nardone, V, Chaves-Sanjuan, A, Lapi, M, Nardini, M.
登録日2020-09-24
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.70001364 Å)
主引用文献Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin.
Cells, 9, 2020
7BFY
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BU of 7bfy by Molmil
Structure of the apo form of the N terminal domain of Bc2L-C lectin (1-131)
分子名称: Lectin
著者Lal, K, Bermeo, R, Imberty, A, Varrot, A.
登録日2021-01-05
公開日2021-04-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Prediction and Validation of a Druggable Site on Virulence Factor of Drug Resistant Burkholderia cenocepacia*.
Chemistry, 27, 2021
8BRO
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BU of 8bro by Molmil
Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-fucosylamide
分子名称: 5-[3-(aminomethyl)phenyl]-~{N}-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]furan-2-carboxamide, Lectin
著者Varrot, A, Lunstrom, J.
登録日2022-11-23
公開日2023-02-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Identification of New L-Fucosyl and L-Galactosyl Amides as Glycomimetic Ligands of TNF Lectin Domain of BC2L-C from Burkholderia cenocepacia.
Molecules, 28, 2023
3V4O
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BU of 3v4o by Molmil
Human MALT1 (caspase domain) in complex with an irreversible peptidic inhibitor
分子名称: MALT1 Inhibitor, Mucosa-associated lymphoid tissue lymphoma translocation protein 1
著者Renatus, M, Wiesmann, C.
登録日2011-12-15
公開日2012-03-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Determinants of MALT1 Protease Activity.
J.Mol.Biol., 419, 2012
3V4L
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BU of 3v4l by Molmil
Mouse MALT1(caspase-IG3 domains) in complex with a irreversible peptidic inhibitor
分子名称: MALT1 Inhibitor, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog
著者Renatus, M, Wiesmann, C.
登録日2011-12-15
公開日2012-03-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural Determinants of MALT1 Protease Activity.
J.Mol.Biol., 419, 2012
3V55
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BU of 3v55 by Molmil
Human MALT1 (334-719) in its ligand free form
分子名称: Mucosa-associated lymphoid tissue lymphoma translocation protein 1
著者Renatus, M, Wiesmann, C.
登録日2011-12-16
公開日2012-03-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Determinants of MALT1 Protease Activity.
J.Mol.Biol., 419, 2012
7OLW
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BU of 7olw by Molmil
Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-N-fucoside ligand
分子名称: 5-(3-aminophenyl)furan-2-carboxamido-(beta-L-fucopyranose), Lectin
著者Bermeo, R, Varrot, A.
登録日2021-05-20
公開日2022-06-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia 's BC2L-C Lectin.
Acs Chem.Biol., 17, 2022
7OLU
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BU of 7olu by Molmil
Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-C-fucoside ligand
分子名称: (2-(4-(beta-L-fucopyranosylethynyl)phenyl)-2-methylpropan-1-amine, Lectin
著者Bermeo, R, Varrot, A.
登録日2021-05-20
公開日2022-06-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.793 Å)
主引用文献Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia 's BC2L-C Lectin.
Acs Chem.Biol., 17, 2022

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