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3V4L

Mouse MALT1(caspase-IG3 domains) in complex with a irreversible peptidic inhibitor

Summary for 3V4L
Entry DOI10.2210/pdb3v4l/pdb
Related3V4O 3V55
Related PRD IDPRD_001076
DescriptorMucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog, MALT1 Inhibitor (2 entities in total)
Functional Keywordscaspase, ig like, hydrolyse, traf6, cytosol, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological sourceMus musculus (mouse)
Cellular locationCytoplasm, perinuclear region : Q2TBA3
Total number of polymer chains2
Total formula weight45267.53
Authors
Renatus, M.,Wiesmann, C. (deposition date: 2011-12-15, release date: 2012-03-14, Last modification date: 2023-11-29)
Primary citationWiesmann, C.,Leder, L.,Blank, J.,Bernardi, A.,Melkko, S.,Decock, A.,D'Arcy, A.,Villard, F.,Erbel, P.,Hughes, N.,Freuler, F.,Nikolay, R.,Alves, J.,Bornancin, F.,Renatus, M.
Structural Determinants of MALT1 Protease Activity.
J.Mol.Biol., 419:4-21, 2012
Cited by
PubMed: 22366302
DOI: 10.1016/j.jmb.2012.02.018
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.15 Å)
Structure validation

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