3TKM
Crystal structure PPAR delta binding GW0742
Summary for 3TKM
Entry DOI | 10.2210/pdb3tkm/pdb |
Descriptor | Peroxisome proliferator-activated receptor delta, {4-[({2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid, GLYCEROL, ... (4 entities in total) |
Functional Keywords | nuclear receptor, transcription, transcription-transcription activator complex, transcription/transcription activator |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 31994.12 |
Authors | Trivella, D.B.B.,Batista, F.H.,Polikarpov, I. (deposition date: 2011-08-27, release date: 2012-07-04, Last modification date: 2023-09-13) |
Primary citation | Batista, F.A.,Trivella, D.B.,Bernardes, A.,Gratieri, J.,Oliveira, P.S.,Figueira, A.C.,Webb, P.,Polikarpov, I. Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding. Plos One, 7:e33643-e33643, 2012 Cited by PubMed: 22606221DOI: 10.1371/journal.pone.0033643 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.953 Å) |
Structure validation
Download full validation report