3TKM
Crystal structure PPAR delta binding GW0742
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Peroxisome proliferator-activated receptor delta | polymer | 275 | 31430.5 | 1 | UniProt (Q03181) Pfam (PF00104) | Homo sapiens (human) | PPAR-delta, NUCI, Nuclear hormone receptor 1, NUC1, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferator-activated receptor beta, PPAR-beta |
2 | B (A) | {4-[({2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid | non-polymer | 471.5 | 1 | Chemie (GW0) | |||
3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | D (A) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 171 - 441 (UniProt: Q03181)
PDB | External Database | Details |
---|---|---|
Gly 167 | - | expression tag |
Ser 168 | - | expression tag |
His 169 | - | expression tag |
Met 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 31430.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 563.6 | |
All* | Total formula weight | 31994.1 |