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3TKM

Crystal structure PPAR delta binding GW0742

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Peroxisome proliferator-activated receptor deltapolymer27531430.51UniProt (Q03181)
Pfam (PF00104)
Homo sapiens (human)PPAR-delta, NUCI, Nuclear hormone receptor 1, NUC1, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferator-activated receptor beta, PPAR-beta
2B
(A)
{4-[({2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acidnon-polymer471.51Chemie (GW0)
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D
(A)
waterwater18.0158Chemie (HOH)
Sequence modifications
A: 171 - 441 (UniProt: Q03181)
PDBExternal DatabaseDetails
Gly 167-expression tag
Ser 168-expression tag
His 169-expression tag
Met 170-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31430.5
Non-Polymers*Number of molecules2
Total formula weight563.6
All*Total formula weight31994.1
*Water molecules are not included.

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PDB entries from 2025-08-06

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