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3UVO
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BU of 3uvo by Molmil
Crystal structure of WDR5 in complex with the WDR5-interacting motif of SET1B
分子名称: Histone-lysine N-methyltransferase SETD1B, WD repeat-containing protein 5
著者Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F.
登録日2011-11-30
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Nucleic Acids Res., 40, 2012
2F5K
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BU of 2f5k by Molmil
Crystal structure of the chromo domain of human MRG15
分子名称: Mortality factor 4-like protein 1
著者Zhang, P, Du, J, Ding, J.
登録日2005-11-26
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.
Nucleic Acids Res., 34, 2006
2F5J
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BU of 2f5j by Molmil
Crystal structure of MRG domain from human MRG15
分子名称: Mortality factor 4-like protein 1
著者Zhang, P, Du, J, Ding, J.
登録日2005-11-26
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14
Protein Sci., 15, 2006
8JES
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BU of 8jes by Molmil
Cryo-EM structure of DltB homo-tetramer
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, DIACYL GLYCEROL, DODECYL-BETA-D-MALTOSIDE, ...
著者Zhang, P, Liu, Z.
登録日2023-05-16
公開日2024-05-22
最終更新日2025-03-12
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
8JF2
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BU of 8jf2 by Molmil
Cryo-EM structure of tetrameric DltB/DltC complex
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, D-alanyl carrier protein, DIACYL GLYCEROL, ...
著者Zhang, P, Liu, Z.
登録日2023-05-17
公開日2024-05-22
最終更新日2025-03-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
8JEM
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BU of 8jem by Molmil
DltB tetramer in complex with inhibitor m-AMSA
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, DIACYL GLYCEROL, DODECYL-BETA-D-MALTOSIDE, ...
著者Zhang, P, Liu, Z.
登録日2023-05-16
公開日2024-05-15
最終更新日2025-03-12
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
8KGC
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BU of 8kgc by Molmil
Cryo-EM structure of human NADK tetramer
分子名称: NAD kinase
著者Zhang, P, Hu, M, Liu, Z.
登録日2023-08-18
公開日2024-08-21
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献Regulation of NADK tetramer conformation and activity by cancer-associated mutants
To Be Published
7FHA
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BU of 7fha by Molmil
Crystal structure of the ATP sulfurylase domain of human PAPSS2 in complex with APS
分子名称: ADENOSINE-5'-PHOSPHOSULFATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, POTASSIUM ION, ...
著者Zhang, P, Zhang, L, Zhang, L.
登録日2021-07-29
公開日2021-12-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the substrate recognition mechanism of ATP-sulfurylase domain of human PAPS synthase 2.
Biochem.Biophys.Res.Commun., 586, 2022
7FH3
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BU of 7fh3 by Molmil
Crystal structure of the ATP sulfurylase domain of human PAPSS2
分子名称: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, SULFATE ION, beta-D-glucopyranose
著者Zhang, P, Zhang, L, Zhang, L.
登録日2021-07-29
公開日2021-12-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the substrate recognition mechanism of ATP-sulfurylase domain of human PAPS synthase 2.
Biochem.Biophys.Res.Commun., 586, 2022
6W9E
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BU of 6w9e by Molmil
Crystal Structure of Human CDK9/cyclinT1 in complex with MC180295
分子名称: (4-amino-2-{[(1R,2R,4S)-bicyclo[2.2.1]heptan-2-yl]amino}-1,3-thiazol-5-yl)(2-nitrophenyl)methanone, (4-amino-2-{[(1S,2S,4R)-bicyclo[2.2.1]heptan-2-yl]amino}-1,3-thiazol-5-yl)(2-nitrophenyl)methanone, Cyclin-T1, ...
著者Zhang, P, Wu, J.
登録日2020-03-22
公開日2021-09-01
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Comparative Modeling of CDK9 Inhibitors to Explore Selectivity and Structure-Activity Relationships
To Be Published
5IMX
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BU of 5imx by Molmil
Anaplastic lymphoma kinase (ALK) catalytic domain complexed with novel inhibitor 3-sulfonylpyrazol-4-amino pyrimidine
分子名称: 5-chloro-N~2~-{5-methyl-4-(1-methylpiperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-N~4~-{1-methyl-3-[(propan-2-yl)sulfonyl]-1H-pyrazol-4-yl}pyrimidine-2,4-diamine, ALK tyrosine kinase receptor
著者Wang, C, Zhang, P, Dong, J.
登録日2016-03-07
公開日2016-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
4HUQ
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BU of 4huq by Molmil
Crystal Structure of a transporter
分子名称: Energy-coupling factor transporter ATP-binding protein EcfA 1, Energy-coupling factor transporter ATP-binding protein EcfA 2, Energy-coupling factor transporter transmembrane protein EcfT, ...
著者Zhang, P, Xu, K, Zhang, M, Zhao, Q, Yu, F.
登録日2012-11-03
公開日2013-04-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.998 Å)
主引用文献Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis.
Nature, 497, 2013
5Z6P
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BU of 5z6p by Molmil
The crystal structure of an agarase, AgWH50C
分子名称: B-agarase
著者Mao, X, Zhou, J, Zhang, P, Zhang, L, Zhang, J, Li, Y.
登録日2018-01-24
公開日2019-01-02
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.061 Å)
主引用文献Structure-based design of agarase AgWH50C from Agarivorans gilvus WH0801 to enhance thermostability.
Appl. Microbiol. Biotechnol., 103, 2019
5HV1
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BU of 5hv1 by Molmil
Rifampin phosphotransferase in complex with AMPPNP and rifampin from Listeria monocytogenes
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphoenolpyruvate synthase, ...
著者Zhang, P, Qi, X.
登録日2016-01-28
公開日2016-03-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.103 Å)
主引用文献Structural basis of rifampin inactivation by rifampin phosphotransferase
Proc.Natl.Acad.Sci.USA, 113, 2016
5HV6
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BU of 5hv6 by Molmil
The ATP binding domain of rifampin phosphotransferase from Listeria monocytogenes
分子名称: Phosphoenolpyruvate synthase
著者Zhang, P, Qi, X.
登録日2016-01-28
公開日2016-03-30
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Structural basis of rifampin inactivation by rifampin phosphotransferase
Proc.Natl.Acad.Sci.USA, 113, 2016
5HV3
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BU of 5hv3 by Molmil
Rifampin phosphotransferase G527Y mutant in complex with AMPPNP from Listeria monocytogenes
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphoenolpyruvate synthase
著者Zhang, P, Qi, X.
登録日2016-01-28
公開日2016-03-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.118 Å)
主引用文献Structural basis of rifampin inactivation by rifampin phosphotransferase
Proc.Natl.Acad.Sci.USA, 113, 2016
5HV2
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BU of 5hv2 by Molmil
Rifampin phosphotransferase G527Y mutant from Listeria monocytogenes
分子名称: Phosphoenolpyruvate synthase
著者Zhang, P, Qi, X.
登録日2016-01-28
公開日2016-03-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.912 Å)
主引用文献Structural basis of rifampin inactivation by rifampin phosphotransferase
Proc.Natl.Acad.Sci.USA, 113, 2016
3BLI
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BU of 3bli by Molmil
Crystal structure of the catalytic domain of LiCMS in complexed with pyruvate and acetyl-CoA
分子名称: ACETYL COENZYME *A, Citramalate synthase from Leptospira interrogans, PYRUVIC ACID, ...
著者Zhang, P, Ma, J.
登録日2007-12-11
公開日2008-11-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular basis of the substrate specificity and the catalytic mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 415, 2008
3BLE
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BU of 3ble by Molmil
Crystal structure of the catalytic domain of LiCMS in complexed with malonate
分子名称: Citramalate synthase from Leptospira interrogans, MALONATE ION, ZINC ION
著者Zhang, P, Ma, J.
登録日2007-12-11
公開日2008-11-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis of the substrate specificity and the catalytic mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 415, 2008
3BLF
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BU of 3blf by Molmil
Crystal structure of the catalytic domain of LiCMS in complexed with pyruvate
分子名称: Citramalate synthase from Leptospira interrogans, PYRUVIC ACID, ZINC ION
著者Zhang, P, Ma, J.
登録日2007-12-11
公開日2008-11-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of the substrate specificity and the catalytic mechanism of citramalate synthase from Leptospira interrogans.
Biochem.J., 415, 2008
6KI2
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BU of 6ki2 by Molmil
The STAS domain of cyanobacteria bicarbonate transporter BicA
分子名称: Low affinity sulfate transporter, SULFATE ION
著者Zhang, P, Wang, C.C.
登録日2019-07-17
公開日2019-11-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.197 Å)
主引用文献Structural mechanism of the active bicarbonate transporter from cyanobacteria.
Nat.Plants, 5, 2019
6KI1
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BU of 6ki1 by Molmil
The transmembrane domain of a cyanobacterium bicarbonate transporter BicA
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, BICARBONATE ION, Low affinity sulfate transporter, ...
著者Zhang, P, Wang, C.C.
登録日2019-07-17
公開日2019-11-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.809 Å)
主引用文献Structural mechanism of the active bicarbonate transporter from cyanobacteria.
Nat.Plants, 5, 2019
5V6J
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BU of 5v6j by Molmil
Glycan binding protein Y3 from mushroom Coprinus comatus possesses anti-leukemic activity
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, TMV resistance protein Y3
著者Li, K, Zhang, P, Gang, Y, Xia, C, Polston, J.E, Li, G, Li, S, Lin, Z, Yang, L.-J, Bruner, S.D, Ding, Y.
登録日2017-03-16
公開日2017-08-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V6I
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BU of 5v6i by Molmil
Glycan binding protein Y3 from mushroom Coprinus comatus possesses anti-leukemic activity - Pt derivative
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, PLATINUM (II) ION, ...
著者Li, K, Zhang, P, Gang, Y, Xia, C, Polston, J.E, Li, G, Li, S, Lin, Z, Yang, L.-J, Bruner, S.D, Ding, Y.
登録日2017-03-16
公開日2017-08-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7V1A
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BU of 7v1a by Molmil
Stapled TBS peptide from RIAM bound to talin R7R8 domains
分子名称: 1,2-ETHANEDIOL, ASP-ILE-ASP-GLN-MET-PHE-SER-THR-LEU-LEU-GLY-GLU-MK8-ASP-LEU-LEU-MK8-GLN-SER, Talin-1
著者Zhang, P, Gao, T, Wu, J.
登録日2022-05-11
公開日2023-06-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.845 Å)
主引用文献Inhibition of talin-induced integrin activation by a double-hit stapled peptide.
Structure, 31, 2023

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