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2KXH
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BU of 2kxh by Molmil
Solution structure of the first two RRM domains of FIR in the complex with FBP Nbox peptide
分子名称: Poly(U)-binding-splicing factor PUF60, peptide of Far upstream element-binding protein 1
著者Cukier, C.D, Ramos, A, Hollingworth, D, Diaz-Moreno, I, Kelly, G.
登録日2010-05-05
公開日2010-08-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Molecular basis of FIR-mediated c-myc transcriptional control.
Nat.Struct.Mol.Biol., 17, 2010
2KXF
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BU of 2kxf by Molmil
Solution structure of the first two RRM domains of FBP-interacting repressor (FIR)
分子名称: Poly(U)-binding-splicing factor PUF60
著者Cukier, C.D, Ramos, A, Hollingworth, D, Diaz-Moreno, I, Kelly, G.
登録日2010-05-04
公開日2010-08-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Molecular basis of FIR-mediated c-myc transcriptional control.
Nat.Struct.Mol.Biol., 17, 2010
6QEY
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BU of 6qey by Molmil
IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties
分子名称: ACETONITRILE, Insulin-like growth factor 2 mRNA-binding protein 1, PHOSPHATE ION
著者Dagil, R, Ball, N.J, Ogrodowicz, R.W, Purkiss, A.G, Taylor, I.A, Ramos, A.
登録日2019-01-09
公開日2019-03-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties.
Nucleic Acids Res., 47, 2019
5FEH
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BU of 5feh by Molmil
Crystal structure of PCT64_35B, a broadly neutralizing anti-HIV antibody
分子名称: 1,2-ETHANEDIOL, PCT64_26 Fab heavy chain, PCT64_26 Fab light chain, ...
著者Murrell, S, Wilson, I.A.
登録日2015-12-17
公開日2017-08-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.
Immunity, 47, 2017
4NPY
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BU of 4npy by Molmil
Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody
分子名称: GLYCEROL, germline PGT121 heavy chain, germline PGT121 light chain
著者Julien, J.-P, Diwanji, D.C, Wilson, I.A.
登録日2013-11-22
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.
Plos Pathog., 9, 2013
5OV3
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BU of 5ov3 by Molmil
Structure of the RbBP5 beta-propeller domain
分子名称: Retinoblastoma-binding protein 5, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL
著者Mittal, A, Zhang, Y, Gamblin, S.J, Wilson, J.R.
登録日2017-08-27
公開日2018-03-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The structure of the RbBP5 beta-propeller domain reveals a surface with potential nucleic acid binding sites.
Nucleic Acids Res., 46, 2018
4GUQ
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BU of 4guq by Molmil
Structure of mutS139F p73 DNA binding domain complexed with 20BP DNA response element
分子名称: DNA (5'-D(P*GP*AP*AP*CP*AP*TP*GP*TP*TP*C)-3'), Tumor protein p73, ZINC ION
著者Ethayathulla, A.S, Nguyen, H.T, Viadiu, H.
登録日2012-08-29
公開日2013-08-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code.
Nucleic Acids Res., 41, 2013
5AWN
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BU of 5awn by Molmil
Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC176 Fab
分子名称: Heavy chain of 3BC176 Fab, Light chain of 3BC176 Fab
著者Lee, J.H, Wilson, I.A, Ward, A.B.
登録日2015-07-06
公開日2015-11-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.887 Å)
主引用文献Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun, 6, 2015
6U6Y
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BU of 6u6y by Molmil
Human SAMHD1 bound to ribo(CGCCU)-oligonucleotide
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, RNA CGCCU, ...
著者Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N.
登録日2019-08-30
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification.
Nat Commun, 12, 2021
5NNQ
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BU of 5nnq by Molmil
Aspartate transcarbamoylase from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate
分子名称: GLYCEROL, ctATC
著者Moreno-Morcillo, M, Grande-Garcia, A, Ramon-Maiques, S.
登録日2017-04-10
公開日2017-06-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
5NNN
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BU of 5nnn by Molmil
Aspartate transcarbamoylase from Chaetomium thermophilum CAD-like
分子名称: GLYCEROL, ctATC
著者Moreno-Morcillo, M, Grande-Garcia, A, Ramon-Maiques, S.
登録日2017-04-10
公開日2017-06-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
5M1G
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BU of 5m1g by Molmil
Structure of a Spumaretrovirus Gag central domain reveals an ancient retroviral capsid
分子名称: Gag protein
著者Nicastro, G, Ball, N, Taylor, I.A.
登録日2016-10-07
公開日2016-10-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid.
Plos Pathog., 12, 2016
3TV3
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BU of 3tv3 by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with Man9
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMYLAMINE, GLYCEROL, ...
著者Pejchal, R, Wilson, I.A.
登録日2011-09-19
公開日2011-10-19
最終更新日2021-04-28
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
3TWC
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BU of 3twc by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT127 in complex with Man9
分子名称: AMYLAMINE, PGT127 heavy chain, Ig gamma-1 chain C region, ...
著者Pejchal, R, Wilson, I.A.
登録日2011-09-21
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
3TYG
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BU of 3tyg by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with a glycosylated engineered gp120 outer domain with miniV3 (eODmV3)
分子名称: Envelope glycoprotein gp160, PGT128 heavy chain, Ig gamma-1 chain C region, ...
著者Pejchal, R, Huang, P.S, Schief, W.R, Stanfield, R.L, Wilson, I.A.
登録日2011-09-25
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
8AG3
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BU of 8ag3 by Molmil
Vaccinia C16 N-terminal domains
分子名称: Protein C10
著者Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
登録日2022-07-19
公開日2022-11-09
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
8AG5
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BU of 8ag5 by Molmil
Vaccinia C16 protein bound to Ku70/Ku80
分子名称: Ku70-Xrcc6, Protein C10, X-ray repair cross-complementing protein 5
著者Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
登録日2022-07-19
公開日2022-11-09
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
8AG4
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BU of 8ag4 by Molmil
Vaccinia C16 protein bound to Ku70/Ku80
分子名称: Protein C10, X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6
著者Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
登録日2022-07-19
公開日2022-11-09
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
5M1H
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BU of 5m1h by Molmil
Structure of a Spumaretrovirus Gag central domain reveals an ancient retroviral capsid
分子名称: Gag protein
著者Taylor, I.A, Nicastro, G, Ball, N.
登録日2016-10-07
公開日2016-10-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid.
Plos Pathog., 12, 2016
5CCK
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BU of 5cck by Molmil
Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC315 Fab
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Antibody 3BC315 Fab heavy chain, Antibody 3BC315 Fab light chain
著者Lee, J.H, Ward, A.B, Wilson, I.A.
登録日2015-07-02
公開日2015-10-07
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun, 6, 2015
5UDG
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BU of 5udg by Molmil
Mutant E97Q crystal structure of Bacillus subtilis QueF with a disulfide Cys 55-99
分子名称: MAGNESIUM ION, NADPH-dependent 7-cyano-7-deazaguanine reductase, TRIETHYLENE GLYCOL
著者Mohammad, A, Kiani, M.K, Iwata-Reuyl, D, Stec, B, Swairjo, M.
登録日2016-12-27
公開日2017-03-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Protection of the Queuosine Biosynthesis Enzyme QueF from Irreversible Oxidation by a Conserved Intramolecular Disulfide.
Biomolecules, 7, 2017
4B50
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BU of 4b50 by Molmil
Crystal structure of the HIV-1 gp41 MPER-specific llama VHH 2H10
分子名称: 2H10 LLAMA VHH
著者Lutje Hulsik, D, Sabin, C, Macheboeuf, P, Weissenhorn, W.
登録日2012-08-02
公開日2013-03-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A Gp41 Mper-Specific Llama Vhh Requires a Hydrophobic Cdr3 for Neutralization But not for Antigen Recognition.
Plos Pathog., 9, 2013
5NNL
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BU of 5nnl by Molmil
Inactive dihydroorotase-like domain of Chaetomium thermophilum CAD-like multifunctional protein
分子名称: Inactive dihydroorotase-like domain
著者Ramon-Maiques, S, Moreno-Morcillo, M, Grande-Garcia, A.
登録日2017-04-10
公開日2017-06-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
7MKC
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BU of 7mkc by Molmil
N74D mutant of the HIV-1 capsid protein in complex with PF-3450074 (PF74)
分子名称: IODIDE ION, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE, capsid protein
著者Kirby, K.A, Sarafianos, S.G.
登録日2021-04-23
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献TRIM5alpha Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection.
Viruses, 14, 2022
7MN0
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BU of 7mn0 by Molmil
N74D mutant of the HIV-1 capsid protein
分子名称: IODIDE ION, capsid protein
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2021-04-30
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献TRIM5alpha Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection.
Viruses, 14, 2022

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