1XBA

Crystal structure of apo syk tyrosine kinase domain

Summary for 1XBA

Entry DOI	10.2210/pdb1xba/pdb
Related	1XBB 1XBC
Descriptor	Tyrosine-protein kinase SYK (2 entities in total)
Functional Keywords	spleen typrosine kinase, active conformation, structural genomics, structural genomix, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	33884.00
Authors	Atwell, S.,Adams, J.M.,Badger, J.,Buchanan, M.D.,Feil, I.K.,Froning, K.J.,Gao, X.,Hendle, J.,Keegan, K.,Leon, B.C.,Muller-Deickmann, H.J.,Nienaber, V.L.,Noland, B.W.,Post, K.,Rajashankar, K.R.,Ramos, A.,Russell, M.,Burley, S.K.,Buchanan, S.G. (deposition date: 2004-08-30, release date: 2004-11-02, Last modification date: 2024-02-14)
Primary citation	Atwell, S.,Adams, J.M.,Badger, J.,Buchanan, M.D.,Feil, I.K.,Froning, K.J.,Gao, X.,Hendle, J.,Keegan, K.,Leon, B.C.,Muller-Deickmann, H.J.,Nienaber, V.L.,Noland, B.W.,Post, K.,Rajashankar, K.R.,Ramos, A.,Russell, M.,Burley, S.K.,Buchanan, S.G. A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase. J.Biol.Chem., 279:55827-55832, 2004 Cited by PubMed: 15507431 DOI: 10.1074/jbc.M409792200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation