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1RTF
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COMPLEX OF BENZAMIDINE WITH THE CATALYTIC DOMAIN OF HUMAN TWO CHAIN TISSUE PLASMINOGEN ACTIVATOR [(TC)-T-PA]
分子名称: BENZAMIDINE, PHOSPHATE ION, TWO CHAIN TISSUE PLASMINOGEN ACTIVATOR
著者Bode, W, Lamba, D.
登録日1995-11-10
公開日1997-01-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator
J.Mol.Biol., 258, 1996
1TOC
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STRUCTURE OF SERINE PROTEINASE
分子名称: ORNITHODORIN, THROMBIN
著者Van De Locht, A, Huber, R, Bode, W.
登録日1996-07-20
公開日1997-07-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The ornithodorin-thrombin crystal structure, a key to the TAP enigma?
EMBO J., 15, 1996
3TPI
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THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, ISOLEUCINE, ...
著者Huber, R, Bode, W, Deisenhofer, J, Schwager, P.
登録日1982-09-27
公開日1983-01-18
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors
Acta Crystallogr.,Sect.B, 39, 1983
3PTN
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ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY
分子名称: CALCIUM ION, TRYPSIN
著者Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R.
登録日1981-10-26
公開日1982-03-04
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Acta Crystallogr.,Sect.B, 38, 1982
4HTC
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THE REFINED STRUCTURE OF THE HIRUDIN-THROMBIN COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
著者Tulinsky, A, Rydel, T.J, Bode, W, Huber, R.
登録日1993-06-25
公開日1994-01-31
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined structure of the hirudin-thrombin complex.
J.Mol.Biol., 221, 1991
2CGA
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BOVINE CHYMOTRYPSINOGEN A. X-RAY CRYSTAL STRUCTURE ANALYSIS AND REFINEMENT OF A NEW CRYSTAL FORM AT 1.8 ANGSTROMS RESOLUTION
分子名称: CHYMOTRYPSINOGEN A
著者Wang, D, Bode, W, Huber, R.
登録日1987-01-16
公開日1987-04-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution.
J.Mol.Biol., 185, 1985
3F6U
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Crystal structure of human Activated Protein C (APC) complexed with PPACK
分子名称: CALCIUM ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, SODIUM ION, ...
著者Schmidt, A.E, Padmanabhan, K, Underwood, M.C, Bode, W, Mather, T, Bajaj, S.P.
登録日2008-11-06
公開日2008-11-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC).
J.Biol.Chem., 277, 2002
3CKI
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Crystal structure of the TACE-N-TIMP-3 complex
分子名称: ADAM 17, Metalloproteinase inhibitor 3, SODIUM ION, ...
著者Wisniewska, M, Goettig, P, Maskos, K, Belouski, E, Winters, D, Hecht, R, Black, R, Bode, W.
登録日2008-03-15
公開日2008-08-05
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex.
J.Mol.Biol., 381, 2008
3HTC
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THE STRUCTURE OF A COMPLEX OF RECOMBINANT HIRUDIN AND HUMAN ALPHA-THROMBIN
分子名称: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN VARIANT 2
著者Tulinsky, A, Rydel, T.J, Ravichandran, K.G, Huber, R, Bode, W.
登録日1993-06-11
公開日1994-01-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of a complex of recombinant hirudin and human alpha-thrombin.
Science, 249, 1990
2TGA
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ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY
分子名称: CALCIUM ION, TRYPSINOGEN
著者Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R.
登録日1981-10-26
公開日1982-03-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Acta Crystallogr.,Sect.B, 38, 1982
2TGT
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ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY
分子名称: CALCIUM ION, METHANOL, TRYPSINOGEN
著者Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R.
登録日1981-10-26
公開日1982-03-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Acta Crystallogr.,Sect.B, 38, 1982
2TPI
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ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY
分子名称: ISOLEUCINE, MERCURY (II) ION, TRYPSIN INHIBITOR, ...
著者Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R.
登録日1981-10-26
公開日1982-03-04
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Acta Crystallogr.,Sect.B, 38, 1982
2PTN
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ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY
分子名称: CALCIUM ION, TRYPSIN
著者Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R.
登録日1981-10-26
公開日1982-03-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Acta Crystallogr.,Sect.B, 38, 1982
5MS3
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Kallikrein-related peptidase 8 calcium complex
分子名称: CALCIUM ION, Kallikrein-8
著者Debela, M, Magdolen, V, Skala, W, Bode, W, Brandstetter, H, Goettig, P.
登録日2016-12-30
公開日2018-01-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Specificity profiles and antagonistic Ca2+ and Zn2+ regulation of human KLK8/neuropsin activity by modules identified in crystal structures
To Be Published
5MS4
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Kallikrein-related peptidase 8 leupeptin inhibitor complex
分子名称: CALCIUM ION, Kallikrein-8, LEUPEPTIN, ...
著者Debela, M, Magdolen, V, Skala, W, Bode, W, Brandstetter, H, Goettig, P.
登録日2016-12-30
公開日2018-01-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin.
Sci Rep, 8, 2018
2TGP
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THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS
分子名称: CALCIUM ION, SULFATE ION, TRYPSIN INHIBITOR, ...
著者Huber, R, Bode, W, Deisenhofer, J, Schwager, P.
登録日1982-09-27
公開日1983-01-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors
Acta Crystallogr.,Sect.B, 39, 1983
1TPP
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THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS
分子名称: (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid, BETA-TRYPSIN, CALCIUM ION, ...
著者Walter, J, Bode, W, Huber, R.
登録日1982-09-27
公開日1983-01-18
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors
Acta Crystallogr.,Sect.B, 39, 1983
1TPA
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THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS
分子名称: ANHYDRO-TRYPSIN, BOVINE PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION
著者Huber, R, Bode, W, Deisenhofer, J.
登録日1982-09-27
公開日1983-01-18
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors
Acta Crystallogr.,Sect.B, 39, 1983
4GWN
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Crystal structure of human mature meprin beta
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X.
登録日2012-09-03
公開日2012-09-19
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane
Proc.Natl.Acad.Sci.USA, 109, 2012
1BTH
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STRUCTURE OF THROMBIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, THROMBIN
著者Van De Locht, A, Bode, W, Stubbs, M.T.
登録日1996-12-03
公開日1997-12-24
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin.
EMBO J., 16, 1997
1A5I
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CATALYTIC DOMAIN OF VAMPIRE BAT (DESMODUS ROTUNDUS) SALIVA PLASMINOGEN ACTIVATOR IN COMPLEX WITH EGR-CMK (GLU-GLY-ARG CHLOROMETHYL KETONE)
分子名称: L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, PLASMINOGEN ACTIVATOR
著者Renatus, M, Stubbs, M.T, Bode, W.
登録日1998-02-17
公開日1999-03-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Catalytic domain structure of vampire bat plasminogen activator: a molecular paradigm for proteolysis without activation cleavage.
Biochemistry, 36, 1997
5LPF
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Kallikrein-related peptidase 10
分子名称: Kallikrein-10, SULFATE ION
著者Goettig, P, Debela, M, Magdolen, V, Bode, W, Brandstetter, H.
登録日2016-08-12
公開日2016-10-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10.
Biol.Chem., 397, 2016
5LPE
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Kallikrein-related peptidase 10 complex with Zn2+
分子名称: Kallikrein-10, SULFATE ION, ZINC ION
著者Goettig, P, Debela, M, Magdolen, V, Bode, W, Brandstetter, H.
登録日2016-08-12
公開日2016-10-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10.
Biol.Chem., 397, 2016
2NSM
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Crystal structure of the human carboxypeptidase N (Kininase I) catalytic domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase N catalytic chain, SULFATE ION
著者Keil, C, Maskos, K, Than, M, Hoopes, J.T, Huber, R, Tan, F, Deddish, P.A, Erdoes, E.G, Skidgel, R.A, Bode, W.
登録日2006-11-05
公開日2007-04-24
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain
J.Mol.Biol., 366, 2007
3OVO
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REFINED X-RAY CRYSTAL STRUCTURES OF THE REACTIVE SITE MODIFIED OVOMUCOID INHIBITOR THIRD DOMAINS FROM SILVER PHEASANT (OMSVP3(ASTERISK)) AND FROM JAPANESE QUAIL (OMJPQ3(ASTERISK))
分子名称: OVOMUCOID THIRD DOMAIN CLEAVED RDI
著者Musil, D, Bode, W.
登録日1991-05-13
公開日1993-01-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Refined X-ray crystal structures of the reactive site modified ovomucoid inhibitor third domains from silver pheasant (OMSVP3*) and from Japanese quail (OMJPQ3*).
J.Mol.Biol., 220, 1991

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