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7EVO
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BU of 7evo by Molmil
The cryo-EM structure of the human 17S U2 snRNP
分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ...
著者Zhang, X, Zhan, X, Shi, Y.
登録日2021-05-21
公開日2022-08-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
8WPU
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BU of 8wpu by Molmil
Human calcium-sensing receptor(CaSR) bound to cinacalcet in complex with Gq protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Ling, S.L, Meng, X.Y, Tian, C.L.
登録日2023-10-10
公開日2023-11-22
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into asymmetric activation of the calcium-sensing receptor-G q complex.
Cell Res., 34, 2024
8WPG
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BU of 8wpg by Molmil
Human calcium-sensing receptor bound with cinacalcet in detergent
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Ling, S.L, Meng, X.Y, Tian, C.L.
登録日2023-10-10
公開日2023-11-22
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural insights into asymmetric activation of the calcium-sensing receptor-G q complex.
Cell Res., 34, 2024
2JTR
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BU of 2jtr by Molmil
rhodanese persulfide from E. coli
分子名称: Phage shock protein E
著者Jin, C, Li, H.
登録日2007-08-06
公開日2008-06-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structures and backbone dynamics of Escherichia coli rhodanese PspE in its sulfur-free and persulfide-intermediate forms: implications for the catalytic mechanism of rhodanese.
Biochemistry, 47, 2008
7JVN
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BU of 7jvn by Molmil
Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor Compound 24
分子名称: 6-(4-amino-4-methylpiperidin-1-yl)-3-[(2,3-dichlorophenyl)sulfanyl]pyrazin-2-amine, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 11
著者Fodor, M, Stams, T.
登録日2020-08-21
公開日2020-09-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.917 Å)
主引用文献Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.
J.Med.Chem., 63, 2020
2JTQ
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BU of 2jtq by Molmil
Rhodanese from E.coli
分子名称: Phage shock protein E
著者Jin, C, Li, H.
登録日2007-08-06
公開日2008-06-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structures and backbone dynamics of Escherichia coli rhodanese PspE in its sulfur-free and persulfide-intermediate forms: implications for the catalytic mechanism of rhodanese.
Biochemistry, 47, 2008
2JSO
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BU of 2jso by Molmil
Antimicrobial resistance protein
分子名称: Polymyxin resistance protein pmrD
著者Jin, C, Fu, W.
登録日2007-07-10
公開日2007-09-04
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献First structure of the polymyxin resistance proteins.
Biochem.Biophys.Res.Commun., 361, 2007
2JTS
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BU of 2jts by Molmil
rhodanese with anions from E. coli
分子名称: Phage shock protein E
著者Jin, C, Li, H.
登録日2007-08-06
公開日2008-06-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structures and backbone dynamics of Escherichia coli rhodanese PspE in its sulfur-free and persulfide-intermediate forms: implications for the catalytic mechanism of rhodanese.
Biochemistry, 47, 2008
2K0N
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BU of 2k0n by Molmil
Solution Structure of Yeast Gal11p kix domain
分子名称: Mediator of RNA polymerase II transcription subunit 15
著者Arthanari, H, Frueh, D.P, Wagner, G.K, Naar, A.M.
登録日2008-02-04
公開日2008-03-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A nuclear receptor-like pathway regulating multidrug resistance in fungi.
Nature, 452, 2008
7JVM
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BU of 7jvm by Molmil
Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor TNO155
分子名称: (3S,4S)-8-{6-amino-5-[(2-amino-3-chloropyridin-4-yl)sulfanyl]pyrazin-2-yl}-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 11
著者Fodor, M, Stams, T.
登録日2020-08-21
公開日2020-09-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.166 Å)
主引用文献Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.
J.Med.Chem., 63, 2020
2JSY
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BU of 2jsy by Molmil
Solution structure of Tpx in the oxidized state
分子名称: Probable thiol peroxidase
著者Jin, C, Lu, J.
登録日2007-07-17
公開日2008-07-22
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Reversible conformational switch revealed by the redox structures of Bacillus subtilis thiol peroxidase
Biochem.Biophys.Res.Commun., 373, 2008
7FDV
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BU of 7fdv by Molmil
Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 1, CHOLESTEROL, ...
著者Xu, D, Li, Y.Y, Yang, F.R, Sun, C.R, Pan, J.H, Wang, L, Chen, Z.P, Fang, S.C, Yao, X.B, Hou, W.T, Zhou, C.Z, Chen, Y.
登録日2021-07-18
公開日2022-06-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structure and transport mechanism of the human cholesterol transporter ABCG1.
Cell Rep, 38, 2022
8H89
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BU of 8h89 by Molmil
Capsid of Ralstonia phage GP4
分子名称: Major capsid protein, Virion associated protein
著者Liu, H.R, Chen, W.Y.
登録日2022-10-22
公開日2022-11-16
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献A Capsid Structure of Ralstonia solanacearum podoviridae GP4 with a Triangulation Number T = 9.
Viruses, 14, 2022
8GVJ
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BU of 8gvj by Molmil
Crystal structure of cMET kinase domain bound by D6808
分子名称: (1^4Z,5^2E)-6^3-(trifluoromethyl)-5^1,5^6-dihydro-1^1H-8-aza-2(3,6)-quinolina-5(1,3)-pyridazina-1(4,1)-pyrazola-6(1,4)-benzenacyclododecaphane-5^6,7-dione, Hepatocyte growth factor receptor
著者Chen, Y.H, Qu, L.Z.
登録日2022-09-15
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment.
J.Med.Chem., 65, 2022
8H3Z
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BU of 8h3z by Molmil
Crystal structure of the effector-binding domain of the LysR-type trasncription factor NtcB from Anabaena PCC 7120
分子名称: IODIDE ION, NtcB
著者Han, S.J, Jiang, Y.L, Zhou, C.Z.
登録日2022-10-09
公開日2023-10-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献DNA looping mediates cooperative transcription activation.
Nat.Struct.Mol.Biol., 31, 2024
8I1V
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BU of 8i1v by Molmil
The asymmetric unit of P22 procapsid
分子名称: Major capsid protein, Scaffolding protein
著者Xiao, H, Liu, H.R, Cheng, L.P.
登録日2023-01-13
公開日2023-03-08
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures.
Viruses, 15, 2023
8I1T
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BU of 8i1t by Molmil
The asymmetric unit of P22 empty capsid
分子名称: Major capsid protein
著者Xiao, H, Liu, H.R, Cheng, L.P.
登録日2023-01-13
公開日2023-03-08
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures.
Viruses, 15, 2023
7VC9
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BU of 7vc9 by Molmil
Tom20 subunits
分子名称: Mitochondrial import receptor subunit TOM20 homolog
著者Liu, D.S, Sui, S.F.
登録日2021-09-02
公開日2022-09-07
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VD2
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BU of 7vd2 by Molmil
Human TOM complex without cross-linking
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, ...
著者Liu, D.S, Sui, S.F.
登録日2021-09-06
公開日2022-07-13
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VDD
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BU of 7vdd by Molmil
Human TOM complex with cross-linking
分子名称: Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, Mitochondrial import receptor subunit TOM5 homolog, ...
著者Liu, D.S, Sui, S.F.
登録日2021-09-06
公開日2022-07-13
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VJT
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BU of 7vjt by Molmil
Crystal Structure of Mtb Pks13-TE in complex with inhibitor coumestan derivative 8
分子名称: 3,8-bis(oxidanyl)-7-(piperidin-1-ylmethyl)-[1]benzofuro[3,2-c]chromen-6-one, Polyketide synthase Pks13 (Termination polyketide synthase)
著者Zhang, W, Wang, S.S, Yu, L.F.
登録日2021-09-28
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structure-Based Optimization of Coumestan Derivatives as Polyketide Synthase 13-Thioesterase(Pks13-TE) Inhibitors with Improved hERG Profiles for Mycobacterium tuberculosis Treatment.
J.Med.Chem., 65, 2022
7VPX
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BU of 7vpx by Molmil
The cryo-EM structure of the human pre-A complex
分子名称: 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ...
著者Zhang, X, Zhan, X, Shi, Y.
登録日2021-10-18
公開日2023-05-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
7CFP
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BU of 7cfp by Molmil
Crystal structure of WDR5 in complex with a H3Q5ser peptide
分子名称: H3Q5ser peptide, SEROTONIN, WD repeat-containing protein 5
著者Zhao, J, Zhang, X, Zang, J.
登録日2020-06-27
公開日2021-07-07
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the recognition of histone H3Q5 serotonylation by WDR5.
Sci Adv, 7, 2021
7CFQ
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BU of 7cfq by Molmil
Crystal structure of WDR5 in complex with H3K4me3Q5ser peptide
分子名称: 1,2-ETHANEDIOL, GLYCEROL, H3K4me3Q5ser peptide, ...
著者Zhao, J, Zhang, X, Zang, J.
登録日2020-06-27
公開日2021-07-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the recognition of histone H3Q5 serotonylation by WDR5.
Sci Adv, 7, 2021
7DFB
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BU of 7dfb by Molmil
Crystal of Arrestin2-V2Rpp-6-7-Fab30 complex
分子名称: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
著者Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
登録日2020-11-06
公開日2021-07-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021

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