4Y47
 
 | | Endothiapepsin in complex with fragment 162 | | 分子名称: | 4-oxo-N-[(1S)-1-(pyridin-3-yl)ethyl]-4-(thiophen-2-yl)butanamide, ACETATE ION, Endothiapepsin, ... | | 著者 | Krimmer, S.G, Krug, M, Uehlein, M, Heine, A, Klebe, G. | | 登録日 | 2015-02-10 | | 公開日 | 2016-02-17 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | Crystallographic Fragment Screening of an Entire Library
To Be Published
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5EQT
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2NYT
 | | The APOBEC2 Crystal Structure and Functional Implications for AID | | 分子名称: | Probable C->U-editing enzyme APOBEC-2, ZINC ION | | 著者 | Prochnow, C, Bransteitter, R, Klein, M, Goodman, M, Chen, X. | | 登録日 | 2006-11-21 | | 公開日 | 2007-01-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The APOBEC-2 crystal structure and functional implications for the deaminase AID.
Nature, 445, 2007
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7P4L
 | | Crystal structure of the trimeric ectodomain of archaeal Fusexin1 (Fsx1) | | 分子名称: | CALCIUM ION, CHLORIDE ION, Fusexin1, ... | | 著者 | Nishio, S, Tunyasuvunakool, K, Jumper, J, De Sanctis, D, Jovine, L. | | 登録日 | 2021-07-12 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins.
Nat Commun, 13, 2022
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1KSR
 | | THE REPEATING SEGMENTS OF THE F-ACTIN CROSS-LINKING GELATION FACTOR (ABP-120) HAVE AN IMMUNOGLOBULIN FOLD, NMR, 20 STRUCTURES | | 分子名称: | GELATION FACTOR | | 著者 | Fucini, P, Renner, C, Herberhold, C, Noegel, A.A, Holak, T.A. | | 登録日 | 1997-02-07 | | 公開日 | 1997-08-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The repeating segments of the F-actin cross-linking gelation factor (ABP-120) have an immunoglobulin-like fold.
Nat.Struct.Biol., 4, 1997
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1PDT
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6DXL
 | | Linked amidobenzimidazole STING agonist | | 分子名称: | 1,1'-(butane-1,4-diyl)bis{2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-1H-benzimidazole-5-carboxamide}, CALCIUM ION, Stimulator of interferon protein | | 著者 | Concha, N.O. | | 登録日 | 2018-06-29 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature, 564, 2018
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6DXG
 | | amidobenzimidazole (ABZI) STING agonists | | 分子名称: | 2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-1-[(2R)-2-hydroxy-2-phenylethyl]-1H-benzimidazole-5-carboxamide, CALCIUM ION, Stimulator of interferon protein | | 著者 | Concha, N.O. | | 登録日 | 2018-06-28 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | | 主引用文献 | Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature, 564, 2018
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2I59
 | | Solution structure of RGS10 | | 分子名称: | Regulator of G-protein signaling 10 | | 著者 | Fedorov, O, Higman, V.A, Diehl, A, Leidert, M, Lemak, A, Schmieder, P, Oschkinat, H, Elkins, J, Soundarajan, M, Doyle, D.A, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Ball, L.J, Structural Genomics Consortium (SGC) | | 登録日 | 2006-08-24 | | 公開日 | 2006-10-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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5DPZ
 | | Endothiapepsin in complex with fragment 31 | | 分子名称: | 2-methylaniline, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Radeva, N, Uehlein, M, Weiss, M, Heine, A, Klebe, G. | | 登録日 | 2015-09-14 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.328 Å) | | 主引用文献 | Crystallographic Fragment Screening of an Entire Library
To Be Published
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5DQ2
 | | Endothiapepsin in complex with fragment 48 | | 分子名称: | 1,2-ETHANEDIOL, Endothiapepsin, GLYCEROL, ... | | 著者 | Radeva, N, Uehlein, M, Weiss, M, Heine, A, Klebe, G. | | 登録日 | 2015-09-14 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.514 Å) | | 主引用文献 | Crystallographic Fragment Screening of an Entire Library
To Be Published
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5NDU
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5NC7
 | | ENAH EVH1 in complex with Ac-WPPPPTEDEL-NH2 | | 分子名称: | ActA-derived 10-mer Ac-FPPPPTEDEL-NH2 with acetylated (Ac) and amidated (NH2) termini. Phe is substitued by Trp to increase affinity for crystallization, Protein enabled homolog | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2017-03-03 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5NEG
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5DQ1
 | | Endothiapepsin in complex with fragment 34 | | 分子名称: | 1,2-ETHANEDIOL, 3-[(cyclopropylamino)methyl]-8-ethylquinolin-2(1H)-one, Endothiapepsin, ... | | 著者 | Radeva, N, Uehlein, M, Weiss, M, Heine, A, Klebe, G. | | 登録日 | 2015-09-14 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.489 Å) | | 主引用文献 | Crystallographic Fragment Screening of an Entire Library
To Be Published
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5NCP
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-12]-OH | | 分子名称: | (3~{S},7~{R},10~{R},13~{R})-4-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-ene-13-carboxylic acid, NITRATE ION, Protein enabled homolog, ... | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2017-03-06 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5NBX
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-PP-[ProM-9]-OH | | 分子名称: | ACY-2L5-PRO-PRO-8SN, BROMIDE ION, Protein enabled homolog | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2017-03-02 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
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3H8N
 | | Crystal Structure Analysis of KIR2DS4 | | 分子名称: | Killer cell immunoglobulin-like receptor 2DS4 | | 著者 | Graef, T, Bushnell, D.A, Parham, P. | | 登録日 | 2009-04-29 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.
J.Exp.Med., 206, 2009
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2JNU
 | | Solution structure of the RGS domain of human RGS14 | | 分子名称: | Regulator of G-protein signaling 14 | | 著者 | Dowler, E.F, Diehl, A, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G.A, Yang, X, Brockmann, C, Leidert, M, Rehbein, K, Schmieder, P, Kuhne, R, Higman, V.A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC) | | 登録日 | 2007-02-02 | | 公開日 | 2007-02-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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5CE4
 | | High Resolution X-Ray and Neutron diffraction structure of H-FABP | | 分子名称: | Fatty acid-binding protein, heart, OLEIC ACID | | 著者 | Podjarny, A.D, Howard, E.I, Blakeley, M.P, Guillot, B. | | 登録日 | 2015-07-06 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | NEUTRON DIFFRACTION (0.98 Å), X-RAY DIFFRACTION | | 主引用文献 | High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP-oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution.
Iucrj, 3, 2016
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5K8Z
 | | Crystal structure of dimeric chlorite dismutase from Cyanothece sp. PCC7425 (pH 8.5) | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Chlorite dismutase, ... | | 著者 | Puehringer, D, Schaffner, I, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | | 登録日 | 2016-05-31 | | 公開日 | 2017-06-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies.
ACS Catal, 7, 2017
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4EFX
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6XVT
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-PPPPTEDDL-NH2 | | 分子名称: | ACY-SC1-SC2-SC3-SC4-SC5-NME, NITRATE ION, Protein enabled homolog, ... | | 著者 | Barone, M, Le Cong, K, Roske, Y. | | 登録日 | 2020-01-22 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6XXR
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3F9V
 | | Crystal Structure Of A Near Full-Length Archaeal MCM: Functional Insights For An AAA+ Hexameric Helicase | | 分子名称: | Minichromosome maintenance protein MCM | | 著者 | Chen, X.J, Brewster, A.S, Wang, G.G, Yu, X, Greenleaf, W, Tjajadi, M, Klein, M. | | 登録日 | 2008-11-14 | | 公開日 | 2008-12-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (4.35 Å) | | 主引用文献 | Crystal structure of a near-full-length archaeal MCM: Functional insights for an AAA+ hexameric helicase.
Proc.Natl.Acad.Sci.USA, 105, 2008
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