8II9
 
 | | crystal structure of Hyp mutant from Hypoxylon sp. E7406B | | 分子名称: | Terpene synthase | | 著者 | Gao, J, Liu, W.D, Li, Q, Han, X, Wei, H.L, Dai, Z.J, Su, L.Q. | | 登録日 | 2023-02-24 | | 公開日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | crystal structure of Hyp
to be published
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1NP5
 | | (GAC)3 parallel duplex | | 分子名称: | 5'-D(*GP*AP*CP*GP*AP*CP*GP*AP*C)-3' | | 著者 | Zheng, M, Han, X, Gao, X. | | 登録日 | 2003-01-17 | | 公開日 | 2003-02-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Strand polarity of trinucleotide repeat sequences:
NMR studies of parallel/anti-pararell duplex,{d(GAC)3}2
To be Published
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8IVP
 | | Crystal structure of MV in complex with LLP and FRU from Mycobacterium vanbaalenii | | 分子名称: | Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase, D-fructose | | 著者 | Li, Q, Zhu, Y.M, Gao, J, Wei, H.L, Han, X, Liu, W.D, Sun, Y.X. | | 登録日 | 2023-03-28 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Crystal structure of MV in complex with LLP and FRU from Mycobacterium vanbaalenii
To Be Published
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5YWW
 | | Archael RuvB-like Holiday junction helicase | | 分子名称: | GLYCEROL, Nucleotide binding protein PINc | | 著者 | Zhai, B, Yuan, Z, Han, X, DuPrez, K, Shen, Y, Fan, L. | | 登録日 | 2017-11-30 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | The archaeal ATPase PINA interacts with the helicase Hjm via its carboxyl terminal KH domain remodeling and processing replication fork and Holliday junction.
Nucleic Acids Res., 46, 2018
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1D59
 | | CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA | | 分子名称: | DNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3') | | 著者 | Kang, C, Zhang, X, Ratliff, R, Moyzis, R, Rich, A. | | 登録日 | 1992-02-25 | | 公開日 | 1993-04-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of four-stranded Oxytricha telomeric DNA.
Nature, 356, 1992
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6H6H
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7SII
 | | Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53) | | 分子名称: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, Stimulator of interferon genes protein, cGAMP | | 著者 | Lu, D, Shang, G, Jie, L, Lu, Y, Bai, X.C, Zhang, X. | | 登録日 | 2021-10-14 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Activation of STING by targeting a pocket in the transmembrane domain.
Nature, 604, 2022
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2M9M
 | | Solution Structure of ERCC4 domain of human FAAP24 | | 分子名称: | Fanconi anemia-associated protein of 24 kDa | | 著者 | Wu, F, Han, X, Shi, C, Gong, W, Tian, C. | | 登録日 | 2013-06-18 | | 公開日 | 2013-09-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response.
Cell Res., 23, 2013
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5V6R
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7CUV
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5V6E
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5V6T
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5V6H
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5V6B
 | | Crystal structure of GIPC1 | | 分子名称: | PDZ domain-containing protein GIPC1 | | 著者 | Shang, G, Zhang, X. | | 登録日 | 2017-03-16 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.
Elife, 6, 2017
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7E30
 | | Crystal structure of a novel alpha/beta hydrolase in apo form in complex with citrate | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CITRIC ACID, SULFATE ION, ... | | 著者 | Gao, J, Han, X, Zheng, Y.Y, Liu, W.D. | | 登録日 | 2021-02-07 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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7E31
 | | Crystal structure of a novel alpha/beta hydrolase mutant in apo form | | 分子名称: | TRIETHYLENE GLYCOL, alpha/beta hydrolase | | 著者 | Gao, J, Han, X, Zheng, Y.Y, Liu, W.D. | | 登録日 | 2021-02-07 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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7E9F
 | | Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucleosome | | 分子名称: | DNA (147-mer), Histone H2A.2, Histone H2B.2, ... | | 著者 | Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. | | 登録日 | 2021-03-04 | | 公開日 | 2022-09-07 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1
To Be Published
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7E9C
 | | Cryo-EM structure of the 1:1 Orc1 BAH domain in complex with nucleosome | | 分子名称: | DNA (147-mer), Histone H2A.2, Histone H2B.2, ... | | 著者 | Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. | | 登録日 | 2021-03-04 | | 公開日 | 2022-09-07 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1
To Be Published
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8AJ8
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6VXK
 | | Cryo-EM Structure of the full-length A39R/PlexinC1 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-C1, Semaphorin-like protein 139 | | 著者 | Kuo, Y.-C, Chen, H, Shang, G, Uchikawa, E, Tian, H, Bai, X, Zhang, X. | | 登録日 | 2020-02-22 | | 公開日 | 2020-04-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activation.
Nat Commun, 11, 2020
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5IJC
 | | The crystal structure of mouse TLR4/MD-2/neoseptin-3 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ... | | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | | 登録日 | 2016-03-01 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5IJB
 | | The ligand-free structure of the mouse TLR4/MD-2 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ... | | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | | 登録日 | 2016-03-01 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
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3FPD
 | | G9a-like protein lysine methyltransferase inhibition by BIX-01294 | | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine, ... | | 著者 | Chang, Y, Zhang, X, Horton, J.R, Cheng, X. | | 登録日 | 2009-01-05 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.
Nat.Struct.Mol.Biol., 16, 2009
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1XOO
 | | NMR structure of G1S mutant of influenza hemagglutinin fusion peptide in DPC micelles at pH 5 | | 分子名称: | Hemagglutinin | | 著者 | Li, Y, Han, X, Lai, A.L, Bushweller, J.H, Cafiso, D.S, Tamm, L.K. | | 登録日 | 2004-10-06 | | 公開日 | 2005-09-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Membrane structures of the hemifusion-inducing fusion peptide mutant G1S and the fusion-blocking mutant G1V of influenza virus hemagglutinin suggest a mechanism for pore opening in membrane fusion.
J.Virol., 79, 2005
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5IJD
 | | The crystal structure of mouse TLR4/MD-2/lipid A complex | | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | | 登録日 | 2016-03-01 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
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