6MPH
| Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DF1W-a.01 Light chain, ... | 著者 | Acharya, P, Xu, K, Kwong, P.D. | 登録日 | 2018-10-06 | 公開日 | 2019-07-24 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
|
|
6N16
| |
6MPG
| Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-b.01 Heavy Chain, ... | 著者 | Acharya, P, Kwong, P.D. | 登録日 | 2018-10-06 | 公開日 | 2019-07-24 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
|
|
6MQE
| |
6MQS
| |
6N1W
| |
6N1V
| |
6MQR
| Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519) | 分子名称: | CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ... | 著者 | Xu, K, Wang, Y, Kwong, P.D. | 登録日 | 2018-10-10 | 公開日 | 2019-07-31 | 最終更新日 | 2019-11-13 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
|
|
6MQM
| |
5WUF
| Structural basis for conductance through TRIC cation channels | 分子名称: | CADMIUM ION, Putative membrane protein | 著者 | Mao, Y, Gao, F, Su, M, Wang, X.H, Zeng, Y, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS) | 登録日 | 2016-12-17 | 公開日 | 2017-08-09 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Structural basis for conductance through TRIC cation channels. Nat Commun, 8, 2017
|
|
6L94
| The structure of the dioxygenase ABH1 from mouse | 分子名称: | FE (II) ION, Nucleic acid dioxygenase ALKBH1 | 著者 | Xie, W, Wang, C, Li, H, Zhang, Y. | 登録日 | 2019-11-08 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.10012341 Å) | 主引用文献 | ALKBH1 promotes lung cancer by regulating m6A RNA demethylation. Biochem Pharmacol, 189, 2021
|
|
6L6W
| The structure of ScoE with intermediate | 分子名称: | (3R)-3-[[(1R)-1,2-bis(oxidanyl)-2-oxidanylidene-ethyl]amino]butanoic acid, FE (II) ION, FORMIC ACID, ... | 著者 | Chen, T.Y, Chen, J, Zhou, J, Chang, W. | 登録日 | 2019-10-29 | 公開日 | 2020-03-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6L6X
| The structure of ScoE with substrate | 分子名称: | (3~{R})-3-(2-hydroxy-2-oxoethylamino)butanoic acid, D(-)-TARTARIC ACID, FE (II) ION, ... | 著者 | Chen, T.Y, Chen, J, Zhou, J, Chang, W. | 登録日 | 2019-10-29 | 公開日 | 2020-03-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6L86
| The structure of SfaA | 分子名称: | (2S)-2-hydroxybutanedioic acid, D-MALATE, FE (II) ION, ... | 著者 | Chen, T.Y, Chen, J, Zhou, J, Chang, W. | 登録日 | 2019-11-05 | 公開日 | 2020-03-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6LNQ
| The co-crystal structure of SARS-CoV 3C Like Protease with aldehyde inhibitor M7 | 分子名称: | N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]-1H-indole-2-carboxamide, Severe Acute Respiratory Syndrome Coronavirus 3c Like Protease | 著者 | Wang, H, Shang, L.Q. | 登録日 | 2020-01-01 | 公開日 | 2020-05-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.244 Å) | 主引用文献 | Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease. Acs Catalysis, 10, 2020
|
|
6LO0
| |
6LNY
| |
6MOH
| Dimeric DARPin C_R3 complex with EpoR | 分子名称: | Dimeric DARPin E2C (C_R3), Erythropoietin receptor, PHOSPHATE ION, ... | 著者 | Jude, K.M, Mohan, K, Garcia, K.C. | 登録日 | 2018-10-04 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
|
|
6MOE
| Monomeric DARPin E2 complex with EpoR | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E2 DARPin, ... | 著者 | Jude, K.M, Mohan, K, Garcia, K.C. | 登録日 | 2018-10-04 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.091 Å) | 主引用文献 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
|
|
6MOF
| Monomeric DARPin G2 complex with EpoR | 分子名称: | 1,2-ETHANEDIOL, Erythropoietin receptor, G2 DARPin | 著者 | Jude, K.M, Mohan, K, Garcia, K.C. | 登録日 | 2018-10-04 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.894 Å) | 主引用文献 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
|
|
6MOG
| Dimeric DARPin C_R3 | 分子名称: | 1,2-ETHANEDIOL, DARPin C_R3, TRIETHYLENE GLYCOL | 著者 | Jude, K.M, Mohan, K, Garcia, K.C. | 登録日 | 2018-10-04 | 公開日 | 2019-06-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
|
|
6MOJ
| Dimeric DARPin A_angle_R5 complex with EpoR | 分子名称: | D(-)-TARTARIC ACID, Dimeric DARPin ACR5 (A_angle_R5), Erythropoietin receptor, ... | 著者 | Jude, K.M, Mohan, K, Garcia, K.C. | 登録日 | 2018-10-04 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.431 Å) | 主引用文献 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
|
|
9DEQ
| Cryo-EM structures of full-length integrin alphaIIbbeta3 in native lipids complexed with modified tirofiban | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A. | 登録日 | 2024-08-29 | 公開日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Platelet integrin alpha IIb beta 3 plays a key role in a venous thrombogenesis mouse model. Nat Commun, 15, 2024
|
|
9DER
| Cryo-EM Structures of Full-Length Integrin alphaIIbbeta3 in Native Lipids Complexed with Tirofiban | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-IIb, ... | 著者 | Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A. | 登録日 | 2024-08-29 | 公開日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Platelet integrin alpha IIb beta 3 plays a key role in a venous thrombogenesis mouse model. Nat Commun, 15, 2024
|
|
4Y5T
| Structure of FtmOx1 apo with metal Iron | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COBALT (II) ION, FE (II) ION, ... | 著者 | Yan, W, Zhang, Y. | 登録日 | 2015-02-12 | 公開日 | 2015-11-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | 主引用文献 | Endoperoxide formation by an alpha-ketoglutarate-dependent mononuclear non-haem iron enzyme. Nature, 527, 2015
|
|