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1HJU
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Structure of two fungal beta-1,4-galactanases: searching for the basis for temperature and pH optimum.
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-1,4-GALACTANASE, ...
著者Le Nours, J, Ryttersgaard, C, Lo Leggio, L, Ostergaard, P.R, Borchert, T.V, Christensen, L.L.H, Larsen, S.
登録日2003-02-27
公開日2003-06-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of Two Fungal Beta-1,4-Galactanases: Searching for the Basis for Temperature and Ph Optimum
Protein Sci., 12, 2003
4K9R
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BU of 4k9r by Molmil
Spore photoproduct lyase Y98F mutant
分子名称: IRON/SULFUR CLUSTER, SULFATE ION, Spore photoproduct lyase, ...
著者Yang, L, Nelson, R.S, Benjdia, A, Lin, G, Telser, J, Stoll, S, Schlichting, I, Li, L.
登録日2013-04-20
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A radical transfer pathway in spore photoproduct lyase.
Biochemistry, 52, 2013
1HJQ
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Structure of two fungal beta-1,4-galactanases: searching for the basis for temperature and pH optimum.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-1,4-GALACTANASE
著者Le Nours, J, Ryttersgaard, C, Lo Leggio, L, Ostergaard, P.R, Borchert, T.V, Christensen, L.L.H, Larsen, S.
登録日2003-02-27
公開日2003-07-25
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of Two Fungal Beta-1,4-Galactanases: Searching for the Basis for Temperature and Ph Optimum
Protein Sci., 12, 2003
1HHY
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BU of 1hhy by Molmil
Deglucobalhimycin in complex with D-Ala-D-Ala
分子名称: (2R,4S,6S)-4-azanyl-4,6-dimethyl-oxane-2,5,5-triol, D-ALANINE, DEGLUCOBALHIMYCIN, ...
著者Lehmann, C, Bunkoczi, G, Sheldrick, G.M, Vertesy, L.
登録日2000-12-29
公開日2003-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (0.89 Å)
主引用文献Structures of Glycopeptide Antibiotics with Peptides that Model Bacterial Cell-Wall Precursors
J.Mol.Biol., 318, 2002
2P6N
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BU of 2p6n by Molmil
Human DEAD-box RNA helicase DDX41, helicase domain
分子名称: ATP-dependent RNA helicase DDX41
著者Karlberg, T, Ogg, D, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2007-03-19
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
1HJM
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HUMAN PRION PROTEIN AT PH 7.0
分子名称: MAJOR PRION PROTEIN PRECURSOR
著者Calzolai, L, Zahn, R.
登録日2003-02-27
公開日2003-07-03
最終更新日2020-01-15
実験手法SOLUTION NMR
主引用文献Influence of Ph on NMR Structure and Stability of the Human Prion Protein Globular Domain
J.Biol.Chem., 278, 2003
1HM8
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BU of 1hm8 by Molmil
CRYSTAL STRUCTURE OF S.PNEUMONIAE N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE, GLMU, BOUND TO ACETYL COENZYME A
分子名称: ACETYL COENZYME *A, CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE
著者Sulzenbacher, G, Gal, L, Peneff, C, Fassy, F, Bourne, Y.
登録日2000-12-05
公開日2001-11-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Streptococcus pneumoniae N-acetylglucosamine-1-phosphate uridyltransferase bound to acetyl-coenzyme A reveals a novel active site architecture.
J.Biol.Chem., 276, 2001
4FLN
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BU of 4fln by Molmil
Crystal structure of plant protease Deg2
分子名称: Protease Do-like 2, chloroplastic, Unknown peptide
著者Gong, W, Liu, L, Sun, R, Gao, F.
登録日2012-06-15
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Arabidopsis deg2 protein reveals an internal PDZ ligand locking the hexameric resting state.
J.Biol.Chem., 287, 2012
6GRY
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BU of 6gry by Molmil
Glucuronoyl Esterase from Solibacter usitatus.
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Putative acetyl xylan esterase, ...
著者Lo Leggio, L, Larsbrink, J, Meland Knudsen, R, Mazurkewich, S, Navarro Poulsen, J.C.
登録日2018-06-12
公開日2018-08-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.0003376 Å)
主引用文献Biochemical and structural features of diverse bacterial glucuronoyl esterases facilitating recalcitrant biomass conversion.
Biotechnol Biofuels, 11, 2018
1HKF
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BU of 1hkf by Molmil
The three dimensional structure of NK cell receptor Nkp44, a triggering partner in natural cytotoxicity
分子名称: NK CELL ACTIVATING RECEPTOR
著者Ponassi, M, Cantoni, C, Biassoni, R, Conte, R, Spallarossa, A, Moretta, A, Moretta, L, Bolognesi, M, Bordo, D.
登録日2003-03-10
公開日2003-06-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Three-Dimensional Structure of the Human Nk Cell Receptor Nkp44, a Triggering Partner in Natural Cytotoxicity
Structure, 11, 2003
6H1Z
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BU of 6h1z by Molmil
AFGH61B WILD-TYPE
分子名称: ACETATE ION, COPPER (II) ION, Endoglucanase, ...
著者Lo Leggio, L, Poulsen, J.C.N.
登録日2018-07-12
公開日2018-08-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structure of a lytic polysaccharide monooxygenase from Aspergillus fumigatus and an engineered thermostable variant.
Carbohydr. Res., 469, 2018
1HM0
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BU of 1hm0 by Molmil
CRYSTAL STRUCTURE OF S.PNEUMONIAE N-ACETYLGLUCOSAMINE 1-PHOSPHATE URIDYLTRANSFERASE, GLMU
分子名称: CALCIUM ION, N-ACETYLGLUCOSAMINE 1-PHOSPHATE URIDYLTRANSFERASE
著者Sulzenbacher, G, Gal, L, Peneff, C, Fassy, F, Bourne, Y.
登録日2000-12-04
公開日2001-11-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Streptococcus pneumoniae N-acetylglucosamine-1-phosphate uridyltransferase bound to acetyl-coenzyme A reveals a novel active site architecture.
J.Biol.Chem., 276, 2001
1HQT
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BU of 1hqt by Molmil
THE CRYSTAL STRUCTURE OF AN ALDEHYDE REDUCTASE Y50F MUTANT-NADP COMPLEX AND ITS IMPLICATIONS FOR SUBSTRATE BINDING
分子名称: ALDEHYDE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Ye, Q, Hyndman, D, Green, N.C, Li, L, Korithoski, B, Jia, Z, Flynn, T.G.
登録日2000-12-19
公開日2001-05-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Crystal Structure of an Aldehyde Reductase Y50F Mutant-NADP Complex and its Implications for Substrate Binding
Chem.Biol.Interact., 132, 2001
1HY8
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BU of 1hy8 by Molmil
SOLUTION STRUCTURE OF B. SUBTILIS ACYL CARRIER PROTEIN
分子名称: ACYL CARRIER PROTEIN
著者Xu, G.-Y, Tam, A, Lin, L, Hixon, J, Fritz, C.C, Power, R.
登録日2001-01-18
公開日2002-01-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of B. subtilis acyl carrier protein.
Structure, 9, 2001
2VS2
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BU of 2vs2 by Molmil
Neutron diffraction structure of endothiapepsin in complex with a gem- diol inhibitor.
分子名称: ENDOTHIAPEPSIN, N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide
著者Coates, L, Tuan, H.-F, Tomanicek, S, Kovalevsky, A, Mustyakimov, M, Erskine, P, Cooper, J.
登録日2008-04-17
公開日2008-05-27
最終更新日2023-11-15
実験手法NEUTRON DIFFRACTION (2 Å)
主引用文献The Catalytic Mechanism of an Aspartic Proteinase Explored with Neutron and X-Ray Diffraction
J.Am.Chem.Soc., 130, 2008
4KFP
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BU of 4kfp by Molmil
Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived Ureas as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT)
分子名称: 1,2-ETHANEDIOL, N-(4-{[1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl]sulfonyl}benzyl)-2H-pyrrolo[3,4-c]pyridine-2-carboxamide, Nicotinamide phosphoribosyltransferase, ...
著者Dragovich, P.S, Bair, K.W, Baumeister, T, Ho, Y, Liederer, B.M, Liu, X, O'Brien, T, Oeh, J, Sampath, D, Skelton, N, Wang, L, Wang, W, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhang, L, Zheng, X.
登録日2013-04-27
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg.Med.Chem.Lett., 23, 2013
1HOV
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BU of 1hov by Molmil
SOLUTION STRUCTURE OF A CATALYTIC DOMAIN OF MMP-2 COMPLEXED WITH SC-74020
分子名称: CALCIUM ION, MATRIX METALLOPROTEINASE-2, N-{4-[(1-HYDROXYCARBAMOYL-2-METHYL-PROPYL)-(2-MORPHOLIN-4-YL-ETHYL)-SULFAMOYL]-4-PENTYL-BENZAMIDE, ...
著者Feng, Y, Likos, J.J, Zhu, L, Woodward, H, Munie, G, McDonald, J.J, Stevens, A.M, Howard, C.P, De Crescenzo, G.A, Welsch, D, Shieh, H.-S, Stallings, W.C.
登録日2000-12-11
公開日2001-12-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor
Biochim.Biophys.Acta, 1598, 2002
1HJK
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ALKALINE PHOSPHATASE MUTANT H331Q
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ...
著者Murphy, J.E, Stec, B, Ma, L, Kantrowitz, E.R.
登録日1997-05-30
公開日1997-10-15
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Trapping and visualization of a covalent enzyme-phosphate intermediate.
Nat.Struct.Biol., 4, 1997
3T3N
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Molecular basis for the recognition and cleavage of RNA (UUCCGU) by the bifunctional 5'-3' exo/endoribonuclease RNase J
分子名称: Metal dependent hydrolase, O2'methyl-RNA, ZINC ION
著者Dorleans, A, Li de la Sierra-Gallay, I, Piton, J, Zig, L, Gilet, L, Putzer, H, Condon, C.
登録日2011-07-25
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Molecular Basis for the Recognition and Cleavage of RNA by the Bifunctional 5'-3' Exo/Endoribonuclease RNase J.
Structure, 19, 2011
3Q47
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Crystal structure of TPR domain of CHIP complexed with pseudophosphorylated Smad1 peptide
分子名称: STIP1 homology and U box-containing protein 1, Smad1 peptide
著者Wang, L, Chen, L, Wu, J.W.
登録日2010-12-23
公開日2011-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.705 Å)
主引用文献Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q49
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Crystal structure of the TPR domain of CHIP complexed with Hsp70-C peptide
分子名称: Hsp70-C peptide, STIP1 homology and U box-containing protein 1
著者Wang, L, Chen, L, Wu, J.W.
登録日2010-12-23
公開日2011-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.543 Å)
主引用文献Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q4H
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Crystal structure of the Mycobacterium smegmatis EsxGH complex (MSMEG_0620-MSMEG_0621)
分子名称: Low molecular weight protein antigen 7, Pe family protein
著者Chan, S, Harris, L, Kuo, E, Ahn, C, Zhou, T.T, Nguyen, L, Shin, A, Sawaya, M.R, Cascio, D, Arbing, M.A, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC)
登録日2010-12-23
公開日2011-01-26
最終更新日2014-05-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
2Q9M
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4-Substituted Trinems as Broad Spectrum-Lactamase Inhibitors: Structure-based Design, Synthesis and Biological Activity
分子名称: (1R,4S,7AS)-1-(1-FORMYLPROP-1-EN-1-YL)-4-METHOXY-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID, Beta-lactamase
著者Plantan, I, Selic, L, Mesar, T, Stefanic Anderluh, P, Oblak, M, Prezelj, A, Hesse, L, Andrejasic, M, Vilar, M, Turk, D, Kocijan, A, Prevec, T, Vilfan, G, Kocjan, D, Copar, A, Urleb, U, Solmajer, T.
登録日2007-06-13
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献4-Substituted Trinems as Broad Spectrum beta-Lactamase Inhibitors: Structure-Based Design, Synthesis, and Biological Activity
J.Med.Chem., 50, 2007
1HW4
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STRUCTURE OF THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS
分子名称: 1,2-ETHANEDIOL, SULFATE ION, THYMIDYLATE SYNTHASE
著者Phan, J, Steadman, J.D, Koli, S, Ding, W.C, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L.
登録日2001-01-09
公開日2001-01-24
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors.
J.Biol.Chem., 276, 2001
3POL
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2.3 Angstrom Crystal Structure of 3-deoxy-manno-octulosonate Cytidylyltransferase (kdsB) from Acinetobacter baumannii.
分子名称: 3-deoxy-manno-octulosonate cytidylyltransferase
著者Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-11-22
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献2.3 Angstrom Crystal Structure of 3-deoxy-manno-octulosonate Cytidylyltransferase (kdsB) from Acinetobacter baumannii.
TO BE PUBLISHED

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