8ITE
 
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3UAI
 | | Structure of the Shq1-Cbf5-Nop10-Gar1 complex from Saccharomyces cerevisiae | | 分子名称: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 3, H/ACA ribonucleoprotein complex subunit 4, ... | | 著者 | Ye, K. | | 登録日 | 2011-10-21 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita
Embo J., 30, 2011
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3UAH
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3GGQ
 | | Dimerization of Hepatitis E Virus Capsid Protein E2s Domain is Essential for Virus-Host Interaction | | 分子名称: | BROMIDE ION, Capsid protein | | 著者 | Li, S.W, Tang, X.H, Seetharaman, J, Yang, C.Y, Gu, Y, Zhang, J, Du, H.L, Shih, J.W.K, Hew, C.L, Sivaraman, J, Xia, N.S. | | 登録日 | 2009-03-02 | | 公開日 | 2009-08-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus-host interaction
Plos Pathog., 5, 2009
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6VNA
 | | Pden_1323 | | 分子名称: | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding protein | | 著者 | Isiorho, E.A, Mansoorabadi, S.O. | | 登録日 | 2020-01-29 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A noncanonical heme oxygenase specific for the degradation of c-type heme.
J.Biol.Chem., 296, 2021
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8T8F
 | | Smc5/6 8mer | | 分子名称: | DNA repair protein KRE29, Non-structural maintenance of chromosome element 4, Non-structural maintenance of chromosome element 5, ... | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2023-06-22 | | 公開日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8T8E
 | | cryoEM structure of Smc5/6 5mer | | 分子名称: | DNA repair protein KRE29, Non-structural maintenance of chromosome element 5, Structural maintenance of chromosomes protein 6 | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2023-06-22 | | 公開日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8H65
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8H66
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8H6C
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8H6D
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3EPM
 | | Crystal structure of Caulobacter crescentus ThiC | | 分子名称: | 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SULFATE ION, Thiamine biosynthesis protein thiC, ... | | 著者 | Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-09-29 | | 公開日 | 2008-10-28 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.793 Å) | | 主引用文献 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
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3EPN
 | | Crystal structure of Caulobacter crescentus ThiC complexed with imidazole ribonucleotide | | 分子名称: | 1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole, Thiamine biosynthesis protein thiC | | 著者 | Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-09-29 | | 公開日 | 2008-10-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
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3EPO
 | | Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P | | 分子名称: | (4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL DIHYDROGEN PHOSPHATE, Thiamine biosynthesis protein thiC | | 著者 | Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-09-29 | | 公開日 | 2008-10-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
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7CAL
 | | Cryo-EM Structure of the Hyperpolarization-Activated Inwardly Rectifying Potassium Channel KAT1 from Arabidopsis | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Potassium channel KAT1 | | 著者 | Li, S.Y, Yang, F, Sun, D.M, Zhang, Y, Zhang, M.G, Zhou, P, Liu, S.L, Zhang, Y.N, Zhang, L.H, Tian, C.L. | | 登録日 | 2020-06-09 | | 公開日 | 2020-07-29 | | 最終更新日 | 2020-11-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis.
Cell Res., 30, 2020
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6M4O
 | | Cryo-EM structure of the monomeric SPT-ORMDL3 complex | | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | | 著者 | Li, S.S, Xie, T, Wang, L, Gong, X. | | 登録日 | 2020-03-08 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
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6M4N
 | | Cryo-EM structure of the dimeric SPT-ORMDL3 complex | | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | | 著者 | Li, S.S, Xie, T, Wang, L, Gong, X. | | 登録日 | 2020-03-07 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
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7CQI
 | | Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex | | 分子名称: | ORM1-like protein 3, Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ... | | 著者 | Li, S.S, Xie, T, Wang, L, Gong, X. | | 登録日 | 2020-08-11 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
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7CQK
 | | Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex | | 分子名称: | ORM1-like protein 3, Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ... | | 著者 | Li, S.S, Xie, T, Wang, L, Gong, X. | | 登録日 | 2020-08-11 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
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7EHL
 | | Cryo-EM structure of human ABCB8 transporter in nucleotide binding state | | 分子名称: | CHOLESTEROL, MAGNESIUM ION, Mitochondrial potassium channel ATP-binding subunit, ... | | 著者 | Li, S.J, Yang, X, Shen, Y.Q. | | 登録日 | 2021-03-29 | | 公開日 | 2021-05-05 | | 実験手法 | ELECTRON MICROSCOPY | | 主引用文献 | Cryo-EM structure of human ABCB8 transporter in nucleotide binding state.
Biochem.Biophys.Res.Commun., 557, 2021
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7EUX
 | | Crystal structure of the Lon-like protease MtaLonC with D581A mutation in complex with substrate polypeptide | | 分子名称: | ALA-PRO-GLU-ALA-VAL, Endopeptidase La, PHOSPHATE ION | | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | | 登録日 | 2021-05-19 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
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7EUY
 | | Crystal structure of the Lon-like protease MtaLonC with D582A mutation in complex with substrate polypeptide | | 分子名称: | ALA-PRO-GLU-ALA-VAL, Endopeptidase La, PHOSPHATE ION | | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | | 登録日 | 2021-05-19 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
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7EV6
 | | Crystal structure of the Lon-like protease MtaLonC with D581A mutation in complex with F-b20-Q | | 分子名称: | Endopeptidase La, F-b20-Q peptide {ortho-aminobenzoic acid (Abz)- QLRSLNGEWRFAWFPAPEAV[Tyr(3-NO2)]A}, PHOSPHATE ION | | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | | 登録日 | 2021-05-20 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
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7EV4
 | | Crystal structure of the Lon-like protease MtaLonC with S582A mutation in complex with F-b20-Q | | 分子名称: | Endopeptidase La, F-b20-Q peptide {ortho-aminobenzoic acid (Abz)- QLRSLNGEWRFAWFPAPEAV[Tyr(3-NO2)]A}, PHOSPHATE ION | | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | | 登録日 | 2021-05-20 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
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7ER2
 | | Crystal structure of EGFR 696-1022 T790M/C797S in complex with LS_2_40 | | 分子名称: | 5-chloranyl-N2-[3-chloranyl-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-N4-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine, Epidermal growth factor receptor | | 著者 | Zhu, S.J, Yun, C.H. | | 登録日 | 2021-05-05 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.662 Å) | | 主引用文献 | Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR T790M/C797S Mutants.
Acs Med.Chem.Lett., 13, 2022
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