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7VNB
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BU of 7vnb by Molmil
Crystal structure of the SARS-CoV-2 RBD in complex with a human single domain antibody n3113
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, n3113
著者Yang, Z, Wang, Y, Kong, Y, Jin, Y, Wu, Y, Ying, T.
登録日2021-10-10
公開日2021-11-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants.
Signal Transduct Target Ther, 6, 2021
7VNC
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BU of 7vnc by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with a human single domain antibody n3113 (UDD-state, state 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yang, Z, Wang, Y, Kong, Y, Jin, Y, Wu, Y, Ying, T.
登録日2021-10-10
公開日2021-11-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants.
Signal Transduct Target Ther, 6, 2021
4N2Q
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BU of 4n2q by Molmil
Crystal structure of THA8 in complex with Zm4 RNA
分子名称: RNA (5'-R(*AP*AP*GP*AP*AP*GP*AP*AP*AP*UP*UP*GP*G)-3'), THA8 RNA binding protein
著者Ke, J, Chen, R.Z, Ban, T, Zhou, X.E, Gu, X, Brunzelle, J.S, Zhu, J.K, Melcher, K, Xu, H.E.
登録日2013-10-06
公開日2013-10-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
4N2S
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BU of 4n2s by Molmil
Crystal Structure of THA8 in complex with Zm1a-6 RNA
分子名称: THA8 RNA binding protein, Zm1a-6 RNA
著者Ke, J, Chen, R.Z, Ban, T, Zhou, X.E, Gu, X, Brunzelle, J.S, Zhu, J.K, Melcher, K, Xu, H.E.
登録日2013-10-06
公開日2013-10-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
4ME2
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BU of 4me2 by Molmil
Crystal Structure of THA8 protein from Brachypodium distachyon
分子名称: Uncharacterized protein
著者Ke, J, Chen, R.Z, Ban, T, Brunzelle, J.S, Gu, X, Melcher, K, Xu, H.E.
登録日2013-08-24
公開日2013-10-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
2DUA
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BU of 2dua by Molmil
Crystal Structure of Phosphonopyruvate Hydrolase Complex with Oxalate and Mg++
分子名称: CHLORIDE ION, MAGNESIUM ION, OXALATE ION, ...
著者Herzberg, O, Chen, C.
登録日2006-07-21
公開日2006-10-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and Kinetics of Phosphonopyruvate Hydrolase from Voriovorax sp. Pal2: New Insight into the Divergence of Catalysis within the PEP Mutase/Isocitrate Lyase Superfamily
Biochemistry, 45, 2006
3C7L
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BU of 3c7l by Molmil
Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation
分子名称: Regulator of G-protein signaling 16
著者Slep, K.C, Kercher, M.A, Wieland, T, Chen, C, Simon, M.I, Sigler, P.B.
登録日2008-02-07
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3C7K
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BU of 3c7k by Molmil
Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(o) subunit alpha, MAGNESIUM ION, ...
著者Slep, K.C, Kercher, M.A, Wieland, T, Chen, C, Simon, M.I, Sigler, P.B.
登録日2008-02-07
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2R82
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BU of 2r82 by Molmil
Pyruvate phosphate dikinase (PPDK) triple mutant R219E/E271R/S262D adapts a second conformational state
分子名称: Pyruvate, phosphate dikinase, SULFATE ION
著者Lim, K, Read, R.J, Chen, C.C, Herzberg, O.
登録日2007-09-10
公開日2008-01-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Swiveling domain mechanism in pyruvate phosphate dikinase.
Biochemistry, 46, 2007
4OA7
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BU of 4oa7 by Molmil
Crystal structure of Tankyrase1 in complex with IWR1
分子名称: 4-[(3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, Tankyrase-1, ZINC ION
著者Zhang, X, He, H.
登録日2014-01-03
公開日2015-01-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Mol.Cell.Biol., 35, 2015
5ZXD
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BU of 5zxd by Molmil
Crystal structure of ATP-bound human ABCF1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family F member 1
著者Qu, L, Jiang, Y, Liu, Z.J.
登録日2018-05-18
公開日2018-07-25
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (2.288 Å)
主引用文献Crystal Structure of ATP-Bound Human ABCF1 Demonstrates a Unique Conformation of ABC Proteins
Structure, 26, 2018
6J3P
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BU of 6j3p by Molmil
Crystal structure of the human GCN5 bromodomain in complex with compound (R,R)-36n
分子名称: 2-{[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methylpiperidin-3-yl]amino}-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2A
著者Huang, L.Y, Li, H, Niu, L, Wu, C.Y, Yu, Y.M, Li, L.L, Yang, S.Y.
登録日2019-01-05
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
J.Med.Chem., 62, 2019
1H65
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BU of 1h65 by Molmil
Crystal structure of pea Toc34 - a novel GTPase of the chloroplast protein translocon
分子名称: CHLOROPLAST OUTER ENVELOPE PROTEIN OEP34, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Sun, Y.J, Forouhar, F, Li, H.M, Tu, S.L, Kao, S, Shr, H.L, Chou, C.C, Hsiao, C.D.
登録日2001-06-06
公開日2002-01-29
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Pea Toc34 - a Novel Gtpase of the Chloroplast Protein Translocon
Nat.Struct.Biol., 9, 2002
1HEV
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BU of 1hev by Molmil
HEVEIN: THE NMR ASSIGNMENT AND AN ASSESSMENT OF SOLUTION-STATE FOLDING FOR THE AGGLUTININ-TOXIN MOTIF
分子名称: HEVEIN
著者Andersen, N.H, Cao, B.
登録日1993-01-14
公開日1994-01-31
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Hevein: NMR assignment and assessment of solution-state folding for the agglutinin-toxin motif.
Biochemistry, 32, 1993
4LGI
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BU of 4lgi by Molmil
N-terminal truncated NleC structure
分子名称: Uncharacterized protein
著者Li, W.Q, Liu, Y.X, Sheng, X.L, Yan, C.Y, Wang, J.W.
登録日2013-06-28
公開日2014-01-15
最終更新日2015-02-25
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure and mechanism of a type III secretion protease, NleC
Acta Crystallogr.,Sect.D, 70, 2014
4I1L
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BU of 4i1l by Molmil
Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function
分子名称: ACETATE ION, Forkhead box protein P3, MAGNESIUM ION, ...
著者Song, X.M, Greene, M.I, Zhou, Z.C.
登録日2012-11-21
公開日2012-12-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function.
Cell Rep, 1, 2012
4LGJ
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BU of 4lgj by Molmil
Crystal structure and mechanism of a type III secretion protease
分子名称: Uncharacterized protein, ZINC ION
著者Li, W.Q, Liu, Y.X, Sheng, X.L, Yan, C.Y, Wang, J.W.
登録日2013-06-28
公開日2014-01-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure and mechanism of a type III secretion protease, NleC
Acta Crystallogr.,Sect.D, 70, 2014
4QTO
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BU of 4qto by Molmil
1.65 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) from Staphylococcus aureus with BME-modified Cys289 and PEG molecule in active site
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Betaine aldehyde dehydrogenase, ...
著者Halavaty, A.S, Minasov, G, Dubrovska, I, Winsor, J, Shuvalova, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-07-08
公開日2014-07-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus.
Acta Crystallogr.,Sect.D, 71, 2015
4S05
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BU of 4s05 by Molmil
Crystal structure of Klebsiella pneumoniae PmrA in complex with PmrA box DNA
分子名称: BERYLLIUM TRIFLUORIDE ION, DNA (26-MER), DNA-binding transcriptional regulator BasR, ...
著者Hsiao, C.D, Weng, T.H, Li, Y.C.
登録日2014-12-30
公開日2015-11-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA.
Nat Commun, 6, 2015
4AE0
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BU of 4ae0 by Molmil
Crystal structure of diphtheria toxin mutant CRM197
分子名称: DIPHTHERIA TOXIN
著者Malito, E, Spraggon, G.
登録日2012-01-04
公開日2012-03-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Structural Basis for Lack of Toxicity of the Diphtheria Toxin Mutant Crm197.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AE1
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BU of 4ae1 by Molmil
Crystal structure of diphtheria toxin mutant CRM197 in complex with nicotinamide
分子名称: DIPHTHERIA TOXIN, NICOTINAMIDE
著者Malito, E, Spraggon, G.
登録日2012-01-04
公開日2012-03-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.078 Å)
主引用文献Structural Basis for Lack of Toxicity of the Diphtheria Toxin Mutant Crm197.
Proc.Natl.Acad.Sci.USA, 109, 2012
4S04
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BU of 4s04 by Molmil
Crystal structure of Klebsiella pneumoniae PmrA in complex with PmrA box DNA
分子名称: BERYLLIUM TRIFLUORIDE ION, DNA (25-MER), DNA-binding transcriptional regulator BasR, ...
著者Hsiao, C.D, Weng, T.H, Li, Y.C.
登録日2014-12-30
公開日2015-11-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA.
Nat Commun, 6, 2015
5WJ8
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BU of 5wj8 by Molmil
Crystal Structure of Human Cadherin-23 EC13-14
分子名称: CALCIUM ION, CHLORIDE ION, Cadherin-23, ...
著者Velez-Cortes, F, Conghui, C, De-la-Torre, P, Sotomayor, M.
登録日2017-07-21
公開日2018-07-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
Structure, 26, 2018
8HJT
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BU of 8hjt by Molmil
Crystal Structure of Intracellular B30.2 Domain of VpBTN3 and VpBTN2 in Complex with HMBPP
分子名称: (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Butyrophylin 3, ...
著者Yang, Y.Y, Shen, P.P, Li, X, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T.
登録日2022-11-23
公開日2023-09-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
7KMK
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BU of 7kmk by Molmil
cryo-EM structure of SARS-CoV-2 spike in complex with Fab 15033-7, two RBDs bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033-7 heavy chain, ...
著者Li, Z, Rini, J.M.
登録日2020-11-03
公開日2021-02-10
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021

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