3C7K

Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation

Summary for 3C7K

Entry DOI	10.2210/pdb3c7k/pdb
Related	3C7L
Descriptor	Guanine nucleotide-binding protein G(o) subunit alpha, Regulator of G-protein signaling 16, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	rgs, galpha, alf4 heterotrimeric g-protein gap, gtp-binding, lipoprotein, myristate, nucleotide-binding, palmitate, transducer, phosphoprotein, signal transduction inhibitor, signaling protein
Biological source	Mus musculus (house mouse) More
Cellular location	Cell membrane : P18872 Membrane ; Lipid-anchor : P97428
Total number of polymer chains	4
Total formula weight	106575.99
Authors	Slep, K.C.,Kercher, M.A.,Wieland, T.,Chen, C.,Simon, M.I.,Sigler, P.B. (deposition date: 2008-02-07, release date: 2008-05-06, Last modification date: 2023-08-30)
Primary citation	Slep, K.C.,Kercher, M.A.,Wieland, T.,Chen, C.K.,Simon, M.I.,Sigler, P.B. Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation. Proc.Natl.Acad.Sci.Usa, 105:6243-6248, 2008 Cited by PubMed: 18434540 DOI: 10.1073/pnas.0801569105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation