3C7K
Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Guanine nucleotide-binding protein G(o) subunit alpha | polymer | 333 | 37854.9 | 2 | UniProt (P18872) Pfam (PF00503) | Mus musculus (house mouse) | Guanine nucleotide-binding protein G(o) subunit alpha |
| 2 | B, D (B, D) | Regulator of G-protein signaling 16 | polymer | 129 | 14862.6 | 2 | UniProt (P97428) Pfam (PF00615) | Mus musculus (house mouse) | RGS16, Retinally abundant regulator of G-protein signaling, RGS-R, A28-RGS14P |
| 3 | E, H (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | F, I (A, C) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 2 | Chemie (ALF) | |||
| 5 | G, J (A, C) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 6 | K, L (A, C) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
B, D: 53 - 180 (UniProt: P97428)
| PDB | External Database | Details |
|---|---|---|
| Gly 52 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 105435.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1141.0 | |
| All* | Total formula weight | 106576.0 |
