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7S20
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BU of 7s20 by Molmil
M. xanthus encapsulin shell protein EncA with T=3 symmetry
分子名称: EncA
著者Eren, E.
登録日2021-09-02
公開日2022-02-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
7S8T
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BU of 7s8t by Molmil
M. xanthus ferritin-like protein EncC
分子名称: EncC, FE (III) ION
著者Eren, E.
登録日2021-09-19
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
7S5C
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BU of 7s5c by Molmil
M. xanthus ferritin-like protein EncB
分子名称: CALCIUM ION, EncB, FE (III) ION
著者Eren, E.
登録日2021-09-10
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
7S5K
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BU of 7s5k by Molmil
M. xanthus ferritin-like protein EncB
分子名称: CALCIUM ION, EncB, FE (III) ION
著者Eren, E.
登録日2021-09-10
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
7S2T
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BU of 7s2t by Molmil
M. xanthus encapsulin EncA bound to EncB targeting peptide
分子名称: EncA, EncB targeting peptide
著者Eren, E.
登録日2021-09-03
公開日2022-02-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
7QQC
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BU of 7qqc by Molmil
Structure of CTX-M-15 K73A mutant
分子名称: Beta-lactamase, CHLORIDE ION, SULFATE ION
著者Tooke, C.L, Hinchliffe, P, Spencer, J.
登録日2022-01-07
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Penicillanic Acid Sulfones Inactivate the Extended-Spectrum beta-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of beta-Lactamase Inhibition.
Mbio, 13, 2022
7QQ5
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BU of 7qq5 by Molmil
Structure of CTX-M-15 K73A mutant crystallised in the presence of enmetazobactam (AAI101)
分子名称: Beta-lactamase, CHLORIDE ION, SULFATE ION
著者Tooke, C.L, Hinchliffe, P, Spencer, J.
登録日2022-01-06
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Penicillanic Acid Sulfones Inactivate the Extended-Spectrum beta-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of beta-Lactamase Inhibition.
Mbio, 13, 2022
8PTP
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BU of 8ptp by Molmil
Structure of Rho pentamer in complex with Rof
分子名称: Protein rof, Transcription termination factor Rho
著者Said, N, Hilal, T, Wahl, M.C.
登録日2023-07-14
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation.
Nat Commun, 15, 2024
8PTN
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BU of 8ptn by Molmil
Structure of the transcription termination factor Rho in complex with Rof
分子名称: Protein rof, Transcription termination factor Rho
著者Said, N, Hilal, T, Wahl, M.C.
登録日2023-07-14
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation.
Nat Commun, 15, 2024
8PTG
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BU of 8ptg by Molmil
Structure of the transcription termination factor Rho bound to RNA at the PBS and SBS
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
著者Said, N, Hilal, T, Wahl, M.C.
登録日2023-07-14
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation.
Nat Commun, 15, 2024
8PTM
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BU of 8ptm by Molmil
Structure of the transcription termination factor Rho in complex with Rof and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein rof, ...
著者Said, N, Hilal, T, Wahl, M.C.
登録日2023-07-14
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation.
Nat Commun, 15, 2024
7SCP
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BU of 7scp by Molmil
The crystal structure of ScoE in complex with intermediate
分子名称: (3R)-3-(oxaloamino)butanoic acid, 1,2-ETHANEDIOL, FE (II) ION, ...
著者Cha, L, Chen, J, Zhou, J, Chang, W.
登録日2021-09-28
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Deciphering the Reaction Pathway of Mononuclear Iron Enzyme-Catalyzed N-C Triple Bond Formation in Isocyanide Lipopeptide and Polyketide Biosynthesis
Acs Catalysis, 12, 2022
8PTO
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BU of 8pto by Molmil
Structure of Rho pentamer in complex with Rof and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Protein rof, Transcription termination factor Rho
著者Said, N, Hilal, T, Wahl, M.C.
登録日2023-07-14
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation.
Nat Commun, 15, 2024
7SMG
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BU of 7smg by Molmil
Crystal structure of a (p)ppApp hydrolase from Bacteroides caccae
分子名称: (p)ppApp hydrolase, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Ahmad, S, Alexei, A.G, Tsang, K.K, Trilesky, S, Kim, Y, Whitney, J.C.
登録日2021-10-25
公開日2022-11-09
最終更新日2023-05-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp.
Proc.Natl.Acad.Sci.USA, 120, 2023
7CHC
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BU of 7chc by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-629 Fab and BD-368-2 Fab
分子名称: BD-368-2 Fab H, BD-368-2 Fab L, BD-629 Fab H, ...
著者Du, S, Xiao, J.Y.
登録日2020-07-05
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
6KJ7
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BU of 6kj7 by Molmil
E. coli ATCase catalytic subunit mutant - G166P
分子名称: Aspartate carbamoyltransferase catalytic subunit
著者Lei, Z, Zheng, J, Jia, Z.
登録日2019-07-21
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.839 Å)
主引用文献New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development.
Febs J., 287, 2020
7CH5
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BU of 7ch5 by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-629 Fab
分子名称: BD-629 Fab H, BD-629 Fab L, Spike protein S1
著者Du, S, Xiao, J.Y.
登録日2020-07-05
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
6KJ9
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BU of 6kj9 by Molmil
E. coli ATCase catalytic subunit mutant - G128/130A
分子名称: Aspartate carbamoyltransferase catalytic subunit
著者Lei, Z, Zheng, J, Jia, Z.C.
登録日2019-07-22
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development.
Febs J., 287, 2020
6KJ8
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BU of 6kj8 by Molmil
E. coli ATCase holoenzyme mutant - G166P (catalytic chain)
分子名称: Aspartate carbamoyltransferase catalytic subunit, Aspartate carbamoyltransferase regulatory chain, ZINC ION
著者Lei, Z, Zheng, J, Jia, Z.C.
登録日2019-07-22
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.011 Å)
主引用文献New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development.
Febs J., 287, 2020
3H5S
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BU of 3h5s by Molmil
Hepatitis C virus polymerase NS5B with saccharin inhibitor
分子名称: (5S)-5-tert-butyl-1-(4-fluoro-3-methylbenzyl)-4-hydroxy-3-[8-(methylsulfonyl)-1,1-dioxido-6,7,8,9-tetrahydroisothiazolo[4,5-h]isoquinolin-3-yl]-1,5-dihydro-2H-pyrrol-2-one, RNA-directed RNA polymerase
著者Harris, S.F, Wong, A.
登録日2009-04-22
公開日2009-09-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides
Bioorg.Med.Chem.Lett., 19, 2009
3H5U
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BU of 3h5u by Molmil
Hepatitis C virus polymerase NS5B with saccharin inhibitor 1
分子名称: N-({3-[(5S)-5-tert-butyl-1-(4-fluorobenzyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1,1-dioxido-1,2-benzisothiazol-7-yl}methyl)methanesulfonamide, RNA-directed RNA polymerase
著者Harris, S.F, Ghate, M.
登録日2009-04-22
公開日2009-09-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides
Bioorg.Med.Chem.Lett., 19, 2009
2REE
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BU of 2ree by Molmil
Crystal structure of the loading GNATL domain of CurA from Lyngbya majuscula
分子名称: CHLORIDE ION, CurA, GLYCEROL, ...
著者Geders, T.W, Smith, J.L.
登録日2007-09-26
公開日2007-11-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献GNAT-like strategy for polyketide chain initiation.
Science, 318, 2007
2F5J
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BU of 2f5j by Molmil
Crystal structure of MRG domain from human MRG15
分子名称: Mortality factor 4-like protein 1
著者Zhang, P, Du, J, Ding, J.
登録日2005-11-26
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14
Protein Sci., 15, 2006
2REF
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BU of 2ref by Molmil
Crystal structure of the loading GNATL domain of CurA from Lyngbya majuscula soaked with malonyl-CoA
分子名称: ACETYL COENZYME *A, CurA
著者Geders, T.W, Smith, J.L.
登録日2007-09-26
公開日2007-11-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献GNAT-like strategy for polyketide chain initiation.
Science, 318, 2007
8HZY
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BU of 8hzy by Molmil
The crystal structure of a Radical SAM Enzyme DesII
分子名称: DesII, IRON/SULFUR CLUSTER, METHIONINE
著者Hou, X.L, Zhou, J.H.
登録日2023-01-10
公開日2024-07-10
実験手法X-RAY DIFFRACTION (2.039788 Å)
主引用文献Mechanistic Insights from the Crystal Structure and Computational Analysis of the Radical SAM Deaminase DesII.
Adv Sci, 2024

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