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6IQI
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BU of 6iqi by Molmil
crystal structure of Arabidopsis thaliana Profilin 2
分子名称: Profilin-2
著者Qiao, Z, Gao, Y.
登録日2018-11-08
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
6IQF
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BU of 6iqf by Molmil
crystal structure of Arabidopsis thaliana Profilin 3
分子名称: PRF3
著者Qiao, Z, Gao, Y.
登録日2018-11-07
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.457 Å)
主引用文献Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
6IQJ
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BU of 6iqj by Molmil
crystal structure of Arabidopsis thaliana Profilin 2 complex with formin1
分子名称: Formin-like protein 1, Profilin-2
著者Qiao, Z, Gao, Y.
登録日2018-11-08
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.922 Å)
主引用文献Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
8H5U
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BU of 8h5u by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-021
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb-021, ...
著者Yang, J, Lin, S, Lu, G.W.
登録日2022-10-13
公開日2023-10-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization.
Plos Pathog., 19, 2023
8H5T
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BU of 8h5t by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-015
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb-015, Spike protein S1
著者Yang, J, Lin, S, Lu, G.W.
登録日2022-10-13
公開日2023-10-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization.
Plos Pathog., 19, 2023
6J67
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BU of 6j67 by Molmil
Crystal structure of the compound 34 in a complex with TRF2
分子名称: 3FB-PHE-B8R-LEU-5XU-PRO, Telomeric repeat-binding factor 2
著者Chen, Y, Yang, Y, Lei, M.
登録日2019-01-14
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Cyclic Peptidic Mimetics of Apollo Peptides Targeting Telomeric Repeat Binding Factor 2 (TRF2) and Apollo Interaction.
ACS Med Chem Lett, 9, 2018
6IQK
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BU of 6iqk by Molmil
crystal structure of Arabidopsis thaliana Profilin 3
分子名称: AtPRF3, Profilin-5
著者Qiao, Z, Gao, Y.
登録日2018-11-08
公開日2019-11-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
6KKN
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BU of 6kkn by Molmil
Crystal structure of RuBisCO accumulation factor Raf1 from Anabaena sp. PCC 7120
分子名称: All5250 protein
著者Xia, L.Y, Jiang, Y.L, Kong, W.W, Chen, Y, Zhou, C.Z.
登録日2019-07-26
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Molecular basis for the assembly of RuBisCO assisted by the chaperone Raf1.
Nat.Plants, 6, 2020
6LRR
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Cryo-EM structure of RuBisCO-Raf1 from Anabaena sp. PCC 7120
分子名称: All5250 protein, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain
著者Xia, L.Y, Jiang, Y.L, Kong, W.W, Chen, Y, Zhou, C.Z.
登録日2020-01-16
公開日2020-05-13
最終更新日2020-07-01
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Molecular basis for the assembly of RuBisCO assisted by the chaperone Raf1.
Nat.Plants, 6, 2020
6LRC
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Human cGAS catalytic domain bound with the inhibitor PF-06928215
分子名称: (1R,2S)-2-[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]cyclohexane-1-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION
著者Zhao, W.F, Xu, Y.C.
登録日2020-01-15
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.831 Å)
主引用文献In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing.
J.Chem.Inf.Model., 60, 2020
6NZR
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BU of 6nzr by Molmil
CRYSTAL STRUCTURE OF TYROSINE KINASE 2 JH2 (PSEUDO KINASE DOMAIN) COMPLEXED WITH Compound_12 AKA 4-[(2-methanesulfonylphenyl)amino]-N-(H3)methyl-6-[(pyridin-2- yl)amino]pyridazine-3-carboxamide
分子名称: N-methyl-4-{[2-(methylsulfonyl)phenyl]amino}-6-[(pyridin-2-yl)amino]pyridazine-3-carboxamide, Non-receptor tyrosine-protein kinase TYK2, SULFATE ION
著者Khan, J.A.
登録日2019-02-14
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165.
J.Med.Chem., 62, 2019
7X4I
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BU of 7x4i by Molmil
Crystal structure of nanobody aSA3 in complex with dimer SARS-CoV-1 RBD
分子名称: Spike glycoprotein, nanobody aSA3
著者Ma, H, Zeng, W.H, Jin, T.C.
登録日2022-03-02
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献A bispecific nanobody dimer broadly neutralizes SARS-CoV-1 & 2 variants of concern and offers substantial protection against Omicron via low-dose intranasal administration.
Cell Discov, 8, 2022
8H2T
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BU of 8h2t by Molmil
Cryo-EM structure of IadD/E dioxygenase bound with IAA
分子名称: 1H-INDOL-3-YLACETIC ACID, Aromatic-ring-hydroxylating dioxygenase beta subunit, FE (III) ION, ...
著者Yu, G, Li, Z, Zhang, H.
登録日2022-10-07
公開日2023-06-14
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Structural and biochemical characterization of the key components of an auxin degradation operon from the rhizosphere bacterium Variovorax.
Plos Biol., 21, 2023
2NWM
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BU of 2nwm by Molmil
Solution structure of the first SH3 domain of human Vinexin and its interaction with the peptides from Vinculin
分子名称: Vinexin
著者Zhang, J, Yao, B, Wu, J, Shi, Y.
登録日2006-11-15
公開日2007-04-24
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the first SH3 domain of human vinexin and its interaction with vinculin peptides
Biochem.Biophys.Res.Commun., 357, 2007
2QN1
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BU of 2qn1 by Molmil
Glycogen Phosphorylase b in complex with asiatic acid
分子名称: Glycogen phosphorylase, muscle form, asiatic acid
著者Zographos, S.E, Leonidas, D.D, Alexacou, K.-M, Hayes, J, Oikonomakos, N.G.
登録日2007-07-17
公開日2008-06-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies
J.Med.Chem., 51, 2008
2QN2
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BU of 2qn2 by Molmil
Glycogen Phosphorylase b in complex with Maslinic Acid
分子名称: Glycogen phosphorylase, muscle form, maslinic acid
著者Zographos, S.E, Leonidas, D.D, Alexacou, K.-M, Hayes, J, Oikonomakos, N.G.
登録日2007-07-17
公開日2008-06-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.698 Å)
主引用文献Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies
J.Med.Chem., 51, 2008
5Y8V
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BU of 5y8v by Molmil
Crystal structure of GAS41
分子名称: MAGNESIUM ION, YEATS domain-containing protein 4
著者Wang, Y, Hao, Q.
登録日2017-08-21
公開日2018-04-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8IA3
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BU of 8ia3 by Molmil
Crystal structure of human USF2 bHLHLZ domain in complex with DNA
分子名称: DNA (5'-D(*GP*CP*GP*CP*GP*TP*CP*AP*CP*GP*TP*GP*CP*CP*CP*GP*TP*C)-3'), DNA (5'-D(P*GP*AP*CP*GP*GP*GP*CP*AP*CP*GP*TP*GP*AP*CP*GP*CP*GP*C)-3'), Upstream stimulatory factor 2
著者Huang, C, Fang, P, Wang, J.
登録日2023-02-07
公開日2023-09-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Tetramerization of upstream stimulating factor USF2 requires the elongated bent leucine zipper of the bHLH-LZ domain.
J.Biol.Chem., 299, 2023
7XE4
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BU of 7xe4 by Molmil
structure of a membrane-bound glycosyltransferase
分子名称: (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, 1,3-beta-glucan synthase component FKS1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hu, X.L, Yang, P, Zhang, M, Liu, X.T, Yu, H.J.
登録日2022-03-29
公開日2023-03-29
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural and mechanistic insights into fungal beta-1,3-glucan synthase FKS1.
Nature, 616, 2023
7DQ7
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BU of 7dq7 by Molmil
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 5F5
分子名称: 5F5 VH, 5F5 VL, Capsid protein VP4, ...
著者Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
登録日2020-12-22
公開日2021-05-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DPF
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BU of 7dpf by Molmil
Cryo-EM structure of Coxsackievirus B1 mature virion
分子名称: Capsid protein VP4, PALMITIC ACID, VP2, ...
著者Zheng, Q, Li, S.
登録日2020-12-18
公開日2021-05-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DQ4
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BU of 7dq4 by Molmil
Cryo-EM structure of CAR triggered Coxsackievirus B1 A-particle
分子名称: VP2, VP3, Virion protein 1
著者Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
登録日2020-12-22
公開日2021-05-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DPZ
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BU of 7dpz by Molmil
Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR
分子名称: Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ...
著者Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
登録日2020-12-22
公開日2021-05-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DQ1
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Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR at physiological temperature
分子名称: Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ...
著者Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
登録日2020-12-22
公開日2021-05-05
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DPG
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BU of 7dpg by Molmil
Cryo-EM structure of Coxsackievirus B1 empty particle
分子名称: VP2, VP3, Virion protein 1
著者Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q, Xia, N.
登録日2020-12-18
公開日2021-05-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021

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