2QN1

Glycogen Phosphorylase b in complex with asiatic acid

Summary for 2QN1

Entry DOI	10.2210/pdb2qn1/pdb
Related	2QN2
Descriptor	Glycogen phosphorylase, muscle form, asiatic acid (3 entities in total)
Functional Keywords	glycogenolysis, type 2 diabetes, transferase, apoptosis
Biological source	Oryctolagus cuniculus (rabbit)
Total number of polymer chains	1
Total formula weight	98008.02
Authors	Zographos, S.E.,Leonidas, D.D.,Alexacou, K.-M.,Hayes, J.,Oikonomakos, N.G. (deposition date: 2007-07-17, release date: 2008-06-03, Last modification date: 2023-11-15)
Primary citation	Wen, X.,Sun, H.,Liu, J.,Cheng, K.,Zhang, P.,Zhang, L.,Hao, J.,Zhang, L.,Ni, P.,Zographos, S.E.,Leonidas, D.D.,Alexacou, K.-M.,Gimisis, T.,Hayes, J.M.,Oikonomakos, N.G. Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies J.Med.Chem., 51:3540-3554, 2008 Cited by PubMed: 18517260 DOI: 10.1021/jm8000949 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.401 Å)

Structure validation