2XRD
 
 | | Structure of the N-terminal four domains of the complement regulator Rat Crry | | 分子名称: | COMPLEMENT REGULATORY PROTEIN CRRY | | 著者 | Leath, K.J, Roversi, P, Johnson, S, Morgan, B.P, Lea, S.M. | | 登録日 | 2010-09-14 | | 公開日 | 2011-06-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structures of the Rat Complement Regulator Crry.
Acta Crystallogr.,Sect.F, 67, 2011
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2XRB
 | | Structure of the N-terminal four domains of the complement regulator Rat Crry | | 分子名称: | 1,2-ETHANEDIOL, COMPLEMENT REGULATORY PROTEIN CRRY, SULFATE ION | | 著者 | Leath, K.J, Roversi, P, Johnson, S, Morgan, B.P, Lea, S.M. | | 登録日 | 2010-09-13 | | 公開日 | 2011-06-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of the Rat Complement Regulator Crry.
Acta Crystallogr.,Sect.F, 67, 2011
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5WEV
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3KHM
 | | Crystal structure of sterol 14alpha-demethylase (CYP51) from Trypanosoma cruzi in complex with inhibitor fluconazole | | 分子名称: | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, PROTOPORPHYRIN IX CONTAINING FE, Sterol 14 alpha-demethylase | | 著者 | Lepesheva, G.I, Hargrove, T.Y, Anderson, S, Wawrzak, Z, Waterman, M.R. | | 登録日 | 2009-10-30 | | 公開日 | 2009-11-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural Insights into Inhibition of Sterol 14{alpha}-Demethylase in the Human Pathogen Trypanosoma cruzi.
J.Biol.Chem., 285, 2010
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3KSW
 | | Crystal structure of sterol 14alpha-demethylase (CYP51) from Trypanosoma cruzi in complex with an inhibitor VNF ((4-(4-chlorophenyl)-N-[2-(1H-imidazol-1-yl)-1-phenylethyl]benzamide) | | 分子名称: | 4'-chloro-N-[(1R)-2-(1H-imidazol-1-yl)-1-phenylethyl]biphenyl-4-carboxamide, PROTOPORPHYRIN IX CONTAINING FE, Sterol 14-alpha demethylase | | 著者 | Lepesheva, G.I, Hargrove, T.Y, Anderson, S, Wawrzak, Z, Waterman, M.R. | | 登録日 | 2009-11-23 | | 公開日 | 2009-12-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural Insights into Inhibition of Sterol 14{alpha}-Demethylase in the Human Pathogen Trypanosoma cruzi.
J.Biol.Chem., 285, 2010
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6NTR
 | | Crystal Structure of Beta-barrel-like Protein of Domain of Unknown Function DUF1849 from Brucella abortus | | 分子名称: | 1,2-ETHANEDIOL, ATP/GTP-binding site-containing protein A, GLYCEROL | | 著者 | Kim, Y, Bigelow, L, Endres, M, Babnigg, G, Crosson, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2019-01-30 | | 公開日 | 2019-02-13 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | BrucellaPeriplasmic Protein EipB Is a Molecular Determinant of Cell Envelope Integrity and Virulence.
J.Bacteriol., 201, 2019
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6NYB
 | | Structure of a MAPK pathway complex | | 分子名称: | 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Park, E, Rawson, S, Li, K, Jeon, H, Eck, M.J. | | 登録日 | 2019-02-11 | | 公開日 | 2019-10-09 | | 最終更新日 | 2020-04-22 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.
Nature, 575, 2019
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3K1O
 | | Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma cruzi in complex with a potential antichagasic drug, posaconazole | | 分子名称: | 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-6-O-{4-[4-(4-{1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenyl}-1-(1H-1,2,4-triazol-1-yl)-D-erythro-hexitol, PROTOPORPHYRIN IX CONTAINING FE, Sterol 14 alpha-demethylase | | 著者 | Lepesheva, G.I, Hargrove, T.Y, Anderson, S, Wawrzak, Z, Waterman, M.R. | | 登録日 | 2009-09-28 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structural Insights into Inhibition of Sterol 14{alpha}-Demethylase in the Human Pathogen Trypanosoma cruzi.
J.Biol.Chem., 285, 2010
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4E4R
 | | EutD phosphotransacetylase from Staphylococcus aureus | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | 著者 | Osipiuk, J, Zhou, M, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-03-13 | | 公開日 | 2012-03-28 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | EutD phosphotransacetylase from Staphylococcus aureus.
To be Published
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8FNW
 | | Structure of RdrA-RdrB complex from Escherichia coli RADAR defense system | | 分子名称: | Adenosine deaminase, Archaeal ATPase, ZINC ION | | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | | 登録日 | 2022-12-28 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (6.73 Å) | | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
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8FNT
 | | Structure of RdrA from Escherichia coli RADAR defense system | | 分子名称: | Archaeal ATPase | | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | | 登録日 | 2022-12-28 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
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8FNV
 | | Structure of RdrB from Escherichia coli RADAR defense system | | 分子名称: | Adenosine deaminase, ZINC ION | | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | | 登録日 | 2022-12-28 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.11 Å) | | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
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8FNU
 | | Structure of RdrA from Streptococcus suis RADAR defense system | | 分子名称: | KAP NTPase domain-containing protein | | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | | 登録日 | 2022-12-28 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
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4E4Y
 | | The crystal structure of a short chain dehydrogenase family protein from Francisella tularensis subsp. tularensis SCHU S4 | | 分子名称: | GLYCEROL, SULFATE ION, Short chain dehydrogenase family protein | | 著者 | Zhang, R, Zhou, M, Tan, K, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-03-13 | | 公開日 | 2012-03-28 | | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | | 主引用文献 | The crystal structure of a short chain dehydrogenase family protein from Francisella tularensis subsp. tularensis SCHU S4
To be Published
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4HV4
 | | 2.25 Angstrom resolution crystal structure of UDP-N-acetylmuramate--L-alanine ligase (murC) from Yersinia pestis CO92 in complex with AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, BETA-MERCAPTOETHANOL, UDP-N-acetylmuramate--L-alanine ligase | | 著者 | Halavaty, A.S, Minasov, G, Dubrovska, I, Winsor, J, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-11-05 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | 2.25 Angstrom resolution crystal structure of UDP-N-acetylmuramate--L-alanine ligase (murC) from Yersinia pestis CO92 in complex with AMP
To be Published
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7LV9
 | | Marseillevirus heterotrimeric (hexameric) nucleosome | | 分子名称: | DNA (96-MER), Histone doublet Beta-Alpha (Alpha), Histone doublet Beta-Alpha (Beta), ... | | 著者 | Valencia-Sanchez, M.I, Abini-Agbomson, S, Armache, K.-J. | | 登録日 | 2021-02-24 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-26 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | The structure of a virus-encoded nucleosome.
Nat.Struct.Mol.Biol., 28, 2021
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7LV8
 | | Structure of the Marseillevirus nucleosome | | 分子名称: | DNA (123-MER), Histone doublet Beta-Alpha (Alpha), Histone doublet Beta-Alpha (Beta), ... | | 著者 | Valencia-Sanchez, M.I, Abini-Agbomson, S, Armache, K.-J. | | 登録日 | 2021-02-24 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-26 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | The structure of a virus-encoded nucleosome.
Nat.Struct.Mol.Biol., 28, 2021
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3SGQ
 | | GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7 | | 分子名称: | Ovomucoid, PHOSPHATE ION, Streptogrisin B | | 著者 | Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G. | | 登録日 | 1999-03-25 | | 公開日 | 2003-08-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18,
Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
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7KKJ
 | | Structure of anti-SARS-CoV-2 Spike nanobody mNb6 | | 分子名称: | CHLORIDE ION, SULFATE ION, Synthetic nanobody mNb6 | | 著者 | Schoof, M.S, Faust, B.F, Saunders, R.A, Sangwan, S, Rezelj, V, Hoppe, N, Boone, M, Billesboelle, C.B, Puchades, C, Azumaya, C.M, Kratochvil, H.T, Zimanyi, M, Desphande, I, Liang, J, Dickinson, S, Nguyen, H.C, Chio, C.M, Merz, G.E, Thompson, M.C, Diwanji, D, Schaefer, K, Anand, A.A, Dobzinski, N, Zha, B.S, Simoneau, C.R, Leon, K, White, K.M, Chio, U.S, Gupta, M, Jin, M, Li, F, Liu, Y, Zhang, K, Bulkley, D, Sun, M, Smith, A.M, Rizo, A.N, Moss, F, Brilot, A.F, Pourmal, S, Trenker, R, Pospiech, T, Gupta, S, Barsi-Rhyne, B, Belyy, V, Barile-Hill, A.W, Nock, S, Liu, Y, Krogan, N.J, Ralston, C.Y, Swaney, D.L, Garcia-Sastre, A, Ott, M, Vignuzzi, M, Walter, P, Manglik, A, QCRG Structural Biology Consortium | | 登録日 | 2020-10-27 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 370, 2020
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7KKK
 | | SARS-CoV-2 Spike in complex with neutralizing nanobody Nb6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Schoof, M.S, Faust, B.F, Saunders, R.A, Sangwan, S, Rezelj, V, Hoppe, N, Boone, M, Billesboelle, C.B, Puchades, C, Azumaya, C.M, Kratochvil, H.T, Zimanyi, M, Desphande, I, Liang, J, Dickinson, S, Nguyen, H.C, Chio, C.M, Merz, G.E, Thompson, M.C, Diwanji, D, Schaefer, K, Anand, A.A, Dobzinski, N, Zha, B.S, Simoneau, C.R, Leon, K, White, K.M, Chio, U.S, Gupta, M, Jin, M, Li, F, Liu, Y, Zhang, K, Bulkley, D, Sun, M, Smith, A.M, Rizo, A.N, Moss, F, Brilot, A.F, Pourmal, S, Trenker, R, Pospiech, T, Gupta, S, Barsi-Rhyne, B, Belyy, V, Barile-Hill, A.W, Nock, S, Liu, Y, Krogan, N.J, Ralston, C.Y, Swaney, D.L, Garcia-Sastre, A, Ott, M, Vignuzzi, M, Walter, P, Manglik, A, QCRG Structural Biology Consortium | | 登録日 | 2020-10-27 | | 公開日 | 2020-11-11 | | 最終更新日 | 2021-04-21 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 370, 2020
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7KKL
 | | SARS-CoV-2 Spike in complex with neutralizing nanobody mNb6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Schoof, M.S, Faust, B.F, Saunders, R.A, Sangwan, S, Rezelj, V, Hoppe, N, Boone, M, Billesboelle, C.B, Puchades, C, Azumaya, C.M, Kratochvil, H.T, Zimanyi, M, Desphande, I, Liang, J, Dickinson, S, Nguyen, H.C, Chio, C.M, Merz, G.E, Thompson, M.C, Diwanji, D, Schaefer, K, Anand, A.A, Dobzinski, N, Zha, B.S, Simoneau, C.R, Leon, K, White, K.M, Chio, U.S, Gupta, M, Jin, M, Li, F, Liu, Y, Zhang, K, Bulkley, D, Sun, M, Smith, A.M, Rizo, A.N, Moss, F, Brilot, A.F, Pourmal, S, Trenker, R, Pospiech, T, Gupta, S, Barsi-Rhyne, B, Belyy, V, Barile-Hill, A.W, Nock, S, Liu, Y, Krogan, N.J, Ralston, C.Y, Swaney, D.L, Garcia-Sastre, A, Ott, M, Vignuzzi, M, Walter, P, Manglik, A, QCRG Structural Biology Consortium | | 登録日 | 2020-10-27 | | 公開日 | 2020-11-11 | | 最終更新日 | 2021-04-21 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 370, 2020
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7TKV
 | | Crystal Structure of the Thioredox_DsbH Domain-Containing Uncharacterized Protein Bab1_2064 from Brucella abortus | | 分子名称: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Kim, Y, Crawford, M, Endres, M, Babnigg, G, Crosson, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-01-17 | | 公開日 | 2022-01-26 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of the Thioredox_DsbH Domain-Containing Uncharacterized Protein Bab1_2064 from Brucella abortus
To Be Published
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7TJ1
 | | Crystal Structure of the Putative Fluoride Ion Transporter CrcB Bab1_1389 from Brucella abortus | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kim, Y, Tesar, C, Pastore, T, Endres, M, Babnigg, G, Crosson, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-01-14 | | 公開日 | 2022-01-26 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the Putative Fluoride Ion Transporter CrcB Bab1_1389 from Brucella abortus
To Be Published
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8DGT
 | | Cryo-EM structure of a RAS/RAF complex (state 2) | | 分子名称: | 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, ... | | 著者 | Eck, M.J, Jeon, H, Park, E, Rawson, S. | | 登録日 | 2022-06-24 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structure of a RAS/RAF recruitment complex.
Nat Commun, 14, 2023
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8DGS
 | | Cryo-EM structure of a RAS/RAF complex (state 1) | | 分子名称: | 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, ... | | 著者 | Eck, M.J, Jeon, H, Park, E, Rawson, S. | | 登録日 | 2022-06-24 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Cryo-EM structure of a RAS/RAF recruitment complex.
Nat Commun, 14, 2023
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