6NYB

Structure of a MAPK pathway complex

Summary for 6NYB

Entry DOI	10.2210/pdb6nyb/pdb
EMDB information	0541
Descriptor	Serine/threonine-protein kinase B-raf, Dual specificity mitogen-activated protein kinase kinase 1, 14-3-3 protein zeta, ... (8 entities in total)
Functional Keywords	transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	193116.14
Authors	Park, E.,Rawson, S.,Li, K.,Jeon, H.,Eck, M.J. (deposition date: 2019-02-11, release date: 2019-10-09, Last modification date: 2020-04-22)
Primary citation	Park, E.,Rawson, S.,Li, K.,Kim, B.W.,Ficarro, S.B.,Pino, G.G.,Sharif, H.,Marto, J.A.,Jeon, H.,Eck, M.J. Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature, 575:545-550, 2019 Cited by PubMed: 31581174 DOI: 10.1038/s41586-019-1660-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.1 Å)

Structure validation