8V9O
| Imaging scaffold engineered to bind the therapeutic protein target BARD1 | 分子名称: | CALCIUM ION, Tetrahedral Nanocage Cage Component Fused to Anti-BARD1 Darpin, Tetrahedral Nanocage Cage, ... | 著者 | Agdanowski, M.P, Castells-Graells, R, Sawaya, M.R, Yeates, T.O, Arbing, M.A. | 登録日 | 2023-12-08 | 公開日 | 2024-05-15 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (3.81 Å) | 主引用文献 | X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. Acta Crystallogr.,Sect.F, 80, 2024
|
|
7K3C
| SGMGGIT segment 58-64 from Keratin-8 | 分子名称: | ETHANOL, SGMGGIT segment 58-64 from the low complexity domain of Keratin-8, TRIETHYLENE GLYCOL | 著者 | Murray, K.A, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2020-09-11 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat.Struct.Mol.Biol., 29, 2022
|
|
7K3Y
| |
7K3X
| |
1NBU
| 7,8-Dihydroneopterin Aldolase Complexed with Product From Mycobacterium Tuberculosis | 分子名称: | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, Probable dihydroneopterin aldolase | 著者 | Goulding, C.W, Apostol, M.I, Sawaya, M.R, Phillips, M, Parseghian, A, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2002-12-03 | 公開日 | 2004-01-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme. J.Mol.Biol., 349, 2005
|
|
1P7G
| Crystal structure of superoxide dismutase from Pyrobaculum aerophilum | 分子名称: | ACETATE ION, BETA-MERCAPTOETHANOL, Superoxide dismutase | 著者 | Lee, S, Sawaya, M.R, Eisenberg, D. | 登録日 | 2003-05-01 | 公開日 | 2003-12-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of superoxide dismutase from Pyrobaculum aerophilum presents a challenging case in molecular replacement with multiple molecules, pseudo-symmetry and twinning. Acta Crystallogr.,Sect.D, 59, 2003
|
|
1PK1
| Hetero SAM domain structure of Ph and Scm. | 分子名称: | Polyhomeotic-proximal chromatin protein, Sex comb on midleg CG9495-PA | 著者 | Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. | 登録日 | 2003-06-04 | 公開日 | 2005-02-15 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. J.Biol.Chem., 280, 2005
|
|
1PK3
| Scm SAM domain | 分子名称: | BETA-MERCAPTOETHANOL, Sex comb on midleg CG9495-PA | 著者 | Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. | 登録日 | 2003-06-04 | 公開日 | 2005-02-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. J.Biol.Chem., 280, 2005
|
|
1OY0
| The crystal Structure of the First Enzyme of Pantothenate Biosynthetic Pathway, Ketopantoate Hydroxymethyltransferase from Mycobacterium Tuberculosis Shows a Decameric Assembly and Terminal Helix-Swapping | 分子名称: | Ketopantoate hydroxymethyltransferase, MAGNESIUM ION | 著者 | Chaudhuri, B.N, Sawaya, M.R, Kim, C.Y, Waldo, G.S, Park, M.S, Terwilliger, T.C, Yeates, T.O, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-04-03 | 公開日 | 2003-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The Crystal Structure of the First Enzyme in the Pantothenate Biosynthetic Pathway,
Ketopantoate Hydroxymethyltransferase, from M. tuberculosis Structure, 11, 2003
|
|
1MZ4
| Crystal Structure of Cytochrome c550 from Thermosynechococcus elongatus | 分子名称: | BICARBONATE ION, GLYCEROL, HEME C, ... | 著者 | Kerfeld, C.A, Sawaya, M.R, Bottin, H, Tran, K.T, Sugiura, M, Kirilovsky, D, Krogmann, D, Yeates, T.O, Boussac, A. | 登録日 | 2002-10-05 | 公開日 | 2003-09-23 | 最終更新日 | 2021-03-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and EPR characterization of the soluble form of cytochrome c-550 and of the psbV2 gene product from the cyanobacterium Thermosynechococcus elongatus. Plant Cell.Physiol., 44, 2003
|
|
1Q57
| The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 | 分子名称: | DNA primase/helicase | 著者 | Toth, E.A, Li, Y, Sawaya, M.R, Cheng, Y, Ellenberger, T. | 登録日 | 2003-08-06 | 公開日 | 2003-11-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 Mol.Cell, 12, 2003
|
|
4M5T
| Disulfide trapped human alphaB crystallin core domain in complex with C-terminal peptide | 分子名称: | Alpha-crystallin B chain, SULFATE ION | 著者 | Laganowsky, A, Cascio, D, Hochberg, G, Sawaya, M.R, Benesch, J.L.P, Robinson, C.V, Eisenberg, D. | 登録日 | 2013-08-08 | 公開日 | 2014-04-09 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4MJH
| |
4NP8
| Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph) | 分子名称: | Microtubule-associated protein tau | 著者 | Landau, M, Eisenberg, D, Sawaya, M.R, Dannenberg, J, Kobko, N. | 登録日 | 2013-11-20 | 公開日 | 2013-12-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Molecular mechanisms for protein-encoded inheritance. Nat.Struct.Mol.Biol., 16, 2009
|
|
4OIJ
| X-ray crystal structure of racemic non-glycosylated chemokine Ser-CCL1 | 分子名称: | C-C motif chemokine 1, D-Ser-CCL1, SULFATE ION | 著者 | Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H. | 登録日 | 2014-01-19 | 公開日 | 2014-05-07 | 最終更新日 | 2014-05-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | (Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis. Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
4OLP
| Ligand-free structure of the GrpU microcompartment shell protein from Pectobacterium wasabiae | 分子名称: | GrpU microcompartment shell protein | 著者 | Wheatley, N.M, Thompson, M.C, Gidaniyan, S.D, Sawaya, M.R, Jorda, J, Yeates, T.O. | 登録日 | 2014-01-24 | 公開日 | 2014-07-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Identification of a unique fe-s cluster binding site in a glycyl-radical type microcompartment shell protein. J.Mol.Biol., 426, 2014
|
|
3CGI
| |
4M5S
| Human alphaB crystallin core domain in complex with C-terminal peptide | 分子名称: | Alpha-crystallin B chain, SUCCINIC ACID | 著者 | Laganowsky, A, Cascio, D, Sawaya, M.R, Eisenberg, D. | 登録日 | 2013-08-08 | 公開日 | 2014-04-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
3CIM
| Carboxysome shell protein, CcmK2 C-terminal deletion mutant | 分子名称: | Carbon dioxide-concentrating mechanism protein ccmK homolog 2, GLYCEROL, SULFATE ION | 著者 | Tanaka, S, Sawaya, M.R, Yeates, T.O. | 登録日 | 2008-03-11 | 公開日 | 2009-02-03 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Insights from multiple structures of the shell proteins from the beta-carboxysome. Protein Sci., 18, 2009
|
|
4OIK
| (Quasi-)Racemic X-ray crystal structure of glycosylated chemokine Ser-CCL1. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1, CITRIC ACID, ... | 著者 | Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H. | 登録日 | 2014-01-19 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | (Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis. Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
4P2S
| Alanine Scanning Mutagenesis Identifies an Asparagine-Arginine-Lysine Triad Essential to Assembly of the Shell of the Pdu Microcompartment | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Putative propanediol utilization protein PduA, ... | 著者 | Sinha, S, Cheng, S, Sung, Y.W, McNamara, D.E, Sawaya, M.R, Yeates, T.O, Bobik, T.A. | 登録日 | 2014-03-03 | 公開日 | 2014-05-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Alanine Scanning Mutagenesis Identifies an Asparagine-Arginine-Lysine Triad Essential to Assembly of the Shell of the Pdu Microcompartment. J.Mol.Biol., 426, 2014
|
|
4NIP
| |
3DNC
| Carboxysome shell protein, CcmK2 C-terminal deletion mutant, with a closer spacing between hexamers | 分子名称: | Carbon dioxide-concentrating mechanism protein ccmK homolog 2, GLYCEROL, SULFATE ION | 著者 | Tanaka, S, Sawaya, M.R, Yeates, T.O. | 登録日 | 2008-07-01 | 公開日 | 2009-01-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Insights from multiple structures of the shell proteins from the beta-carboxysome. Protein Sci., 18, 2009
|
|
4NIN
| |
4NIO
| |