8HIT
| Crystal structure of anti-CTLA-4 humanized IgG1 MAb--JS007 in complex with human CTLA-4 | 分子名称: | Cytotoxic T-lymphocyte protein 4, JS007-VH, JS007-VL | 著者 | Tan, S, Shi, Y, Wang, Q, Gao, G.F, Guan, J, Chai, Y, Qi, J. | 登録日 | 2022-11-21 | 公開日 | 2023-02-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Characterization of the high-affinity anti-CTLA-4 monoclonal antibody JS007 for immune checkpoint therapy of cancer. Mabs, 15, 2023
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8H06
| Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with human ACE2 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2022-09-28 | 公開日 | 2023-07-19 | 最終更新日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
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8H5C
| Structure of SARS-CoV-2 Omicron BA.2.75 RBD in complex with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Z.N, Bai, B, Liu, K.F, Qi, J.X, Gao, G.F. | 登録日 | 2022-10-12 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
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8I5D
| Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) | 分子名称: | Beta-2-microglobulin, MHC class I antigen (Fragment), TCR alpha chain, ... | 著者 | Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F. | 登録日 | 2023-01-25 | 公開日 | 2023-08-23 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) Nat Commun, 2023
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7YA1
| Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2022-06-27 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-07 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape. Nat Commun, 13, 2022
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7Y9S
| Cryo-EM structure of apo SARS-CoV-2 Omicron spike protein (S-2P-GSAS) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2022-06-26 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-07 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape. Nat Commun, 13, 2022
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7YE7
| Crystal structure of SARS-CoV-2 soluble dimeric ORF9b | 分子名称: | N-OCTANE, ORF9b protein, nonane | 著者 | Jin, X, Chai, Y, Qi, J, Song, H, Gao, G.F. | 登録日 | 2022-07-05 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural characterization of SARS-CoV-2 dimeric ORF9b reveals potential fold-switching trigger mechanism. Sci China Life Sci, 66, 2023
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7YE8
| Crystal structure of SARS-CoV-2 refolded dimeric ORF9b | 分子名称: | N-OCTANE, ORF9b protein | 著者 | Jin, X, Chai, Y, Qi, J, Song, H, Gao, G.F. | 登録日 | 2022-07-05 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Structural characterization of SARS-CoV-2 dimeric ORF9b reveals potential fold-switching trigger mechanism. Sci China Life Sci, 66, 2023
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7YA0
| Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (S-6P-RRAR) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2022-06-26 | 公開日 | 2022-09-21 | 最終更新日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape. Nat Commun, 13, 2022
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5X5B
| Prefusion structure of SARS-CoV spike glycoprotein, conformation 2 | 分子名称: | Spike glycoprotein | 著者 | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | 登録日 | 2017-02-15 | 公開日 | 2017-05-03 | 最終更新日 | 2017-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5X5W
| Crystal structure of pseudorabies virus glycoprotein D | 分子名称: | GD, Nectin-1 | 著者 | Li, A, Lu, G, Qi, J, Wu, L, Tian, K, Luo, T, Shi, Y, Yan, J, Gao, G.F. | 登録日 | 2017-02-17 | 公開日 | 2017-04-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of pseudorabies virus glycoprotein D To Be Published
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5XL7
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5X59
| Prefusion structure of MERS-CoV spike glycoprotein, three-fold symmetry | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | 著者 | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | 登録日 | 2017-02-15 | 公開日 | 2017-05-03 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5XEA
| Structure of Thogoto virus envelope glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ... | 著者 | Peng, R, Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2017-04-03 | 公開日 | 2017-10-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | 主引用文献 | Structures of human-infecting Thogotovirus fusogens support a common ancestor with insect baculovirus Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XLB
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5XL2
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5YMV
| Crystal structure of 9-mer peptide from influenza virus in complex with BF2*1201 | 分子名称: | ALA-VAL-LYS-GLY-VAL-GLY-THR-MET-VAL, Beta-2-microglobulin, Class I histocompatibility antigen, ... | 著者 | Xiao, J, Xiang, W, Qi, J, Chai, Y, Liu, W.J, Gao, G.F. | 登録日 | 2017-10-22 | 公開日 | 2018-10-24 | 最終更新日 | 2019-07-31 | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | 主引用文献 | An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I. J Immunol., 201, 2018
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5YMW
| Crystal structure of 8-mer peptide from Rous sarcoma virus in complex with BF2*1201 | 分子名称: | Beta-2-microglobulin, Class I histocompatibility antigen, F10 alpha chain, ... | 著者 | Xiao, J, Xiang, W, Qi, J, Chai, Y, Liu, W.J, Gao, G.F. | 登録日 | 2017-10-22 | 公開日 | 2018-10-24 | 最終更新日 | 2019-07-31 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I. J Immunol., 201, 2018
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5YGH
| Crystal Structure of the Capsid Protein from Zika Virus | 分子名称: | Capsid protein | 著者 | Shang, Z, Song, H, Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2017-09-23 | 公開日 | 2018-02-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.884 Å) | 主引用文献 | Crystal Structure of the Capsid Protein from Zika Virus. J. Mol. Biol., 430, 2018
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5WZ1
| Crystal structure of Zika virus NS5 methyltransferase bound to S-adenosyl-L-methionine | 分子名称: | NS5 methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Duan, W, Song, H, Qi, J, Shi, Y, Gao, G.F. | 登録日 | 2017-01-16 | 公開日 | 2017-03-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.507 Å) | 主引用文献 | The crystal structure of Zika virus NS5 reveals conserved drug targets. EMBO J., 36, 2017
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5WWI
| Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1) | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | 著者 | Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F. | 登録日 | 2017-01-01 | 公開日 | 2018-01-17 | 最終更新日 | 2019-07-31 | 実験手法 | X-RAY DIFFRACTION (3.194 Å) | 主引用文献 | Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1). To Be Published
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5WXC
| Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 2) | 分子名称: | Beta-2-microglobulin, H7-25-F, HLA class I histocompatibility antigen, ... | 著者 | Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F. | 登録日 | 2017-01-07 | 公開日 | 2018-01-17 | 最終更新日 | 2019-07-31 | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | 主引用文献 | Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses. Mbio, 9, 2018
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5WZ2
| Crystal structure of Zika virus NS5 methyltransferase bound to SAM and RNA analogue (m7GpppA) | 分子名称: | NS5 MTase, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYLMETHIONINE | 著者 | Duan, W, Song, H, Qi, J, Shi, Y, Gao, G.F. | 登録日 | 2017-01-16 | 公開日 | 2017-03-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The crystal structure of Zika virus NS5 reveals conserved drug targets. EMBO J., 36, 2017
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5Z38
| Crystal structure of CsrA bound to CesT | 分子名称: | CesT protein, Truncated-CsrA, wild type CsrA | 著者 | Ye, F, Yang, F, Yu, R, Lin, X, Qi, J, Chen, Z, Gao, G.F, Lu, G. | 登録日 | 2018-01-05 | 公開日 | 2018-04-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | 主引用文献 | Molecular basis of binding between the global post-transcriptional regulator CsrA and the T3SS chaperone CesT Nat Commun, 9, 2018
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5XL5
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