1KQW
 
 | Crystal structure of holo-CRBP from zebrafish | 分子名称: | Cellular retinol-binding protein, RETINOL | 著者 | Calderone, V, Folli, C, Marchesani, A, Berni, R, Zanotti, G. | 登録日 | 2002-01-08 | 公開日 | 2002-08-28 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Identification and structural analysis of a zebrafish apo and holo cellular retinol-binding protein. J.Mol.Biol., 321, 2002
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7F9W
 
 | CD25 in complex with Fab | 分子名称: | Heavy chain of Fab, Interleukin-2 receptor subunit alpha, Light chain of Fab | 著者 | Liu, C. | 登録日 | 2021-07-05 | 公開日 | 2022-01-12 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity. Sci Rep, 11, 2021
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4URV
 
 | The crystal structure of H-Ras and SOS in complex with ligands | 分子名称: | 4-(4-BROMOPHENYL)PIPERIDIN-4-OL, FORMIC ACID, GTPASE HRAS, ... | 著者 | Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. | 登録日 | 2014-07-02 | 公開日 | 2015-03-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
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4CG9
 
 | Human choline kinase a1 in complex with compound 12 | 分子名称: | CHOLINE KINASE ALPHA, N,N-dimethyl-1-[(4-phenylphenyl)methyl]pyridin-1-ium-4-amine | 著者 | Rubio-Ruiz, B, Figuerola-Conchas, A, Ramos-Torrecillas, J, Capitan-Canadas, F, Rios-Marco, P, Carrasco, M.P, Gallo, M.A, Espinosa, A, Marco, C, Concepcion, C, Entrena-Guadix, A, Hurtado-Guerrero, R, Conejo-Garcia, A. | 登録日 | 2013-11-21 | 公開日 | 2014-01-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Discovery of a New Binding Site on Human Choline Kinase A1: Design, Synthesis, Crystallographic Studies and Biological Evaluation of Asymmetrical Bispyridinium Derivatives J.Med.Chem., 57, 2014
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1KWO
 
 | SCALLOP MYOSIN S1-ATPgammaS-p-PDM IN THE ACTIN-DETACHED CONFORMATION | 分子名称: | 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. | 登録日 | 2002-01-30 | 公開日 | 2002-11-20 | 最終更新日 | 2024-12-25 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Crystallographic findings on the
internally uncoupled and near-rigor
states of myosin: Further insights into
the mechanics of the motor Proc.Natl.Acad.Sci.USA, 99, 2002
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4CGA
 
 | Human choline kinase a1 in complex with compound 5 | 分子名称: | CHOLINE KINASE ALPHA, N,N-dimethyl-1-[[4-(2-phenylethyl)phenyl]methyl]pyridin-1-ium-4-amine | 著者 | Rubio-Ruiz, B, Figuerola-Conchas, A, Ramos-Torrecillas, J, Capitan-Canadas, F, Rios-Marco, P, Carrasco, M.P, Gallo, M.A, Espinosa, A, Marco, C, Concepcion, C, Entrena-Guadix, A, Hurtado-Guerrero, R, Conejo-Garcia, A. | 登録日 | 2013-11-21 | 公開日 | 2014-01-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Discovery of a New Binding Site on Human Choline Kinase A1: Design, Synthesis, Crystallographic Studies and Biological Evaluation of Asymmetrical Bispyridinium Derivatives J.Med.Chem., 57, 2014
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1KVV
 
 | Solution Structure Of Protein SRP19 Of The Archaeoglobus fulgidus Signal Recognition Particle, Minimized Average Structure | 分子名称: | SRP19 | 著者 | Pakhomova, O.N, Deep, S, Huang, Q, Zwieb, C, Hinck, A.P. | 登録日 | 2002-01-27 | 公開日 | 2002-03-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of protein SRP19 of Archaeoglobus fulgidus signal recognition particle. J.Mol.Biol., 317, 2002
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6LAE
 
 | Crystal structure of the DNA-binding domain of human XPA in complex with DNA | 分子名称: | DNA (5'-D(P*GP*CP*AP*TP*CP*TP*CP*GP*CP*CP*T)-3'), DNA (5'-D(P*TP*GP*GP*CP*GP*AP*GP*AP*TP*GP*C)-3'), DNA repair protein complementing XP-A cells, ... | 著者 | Lian, F.M, Yang, X, Jiang, Y.L, Yang, F, Li, C, Yang, W, Qian, C. | 登録日 | 2019-11-12 | 公開日 | 2020-02-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | New structural insights into the recognition of undamaged splayed-arm DNA with a single pair of non-complementary nucleotides by human nucleotide excision repair protein XPA. Int.J.Biol.Macromol., 148, 2020
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4V0S
 
 | Crystal structure of Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant inhibited by a 3-dehydroquinic acid derivative | 分子名称: | (1R,2S,4S,5R)-2-(2,3,4,5,6-pentafluorophenyl)methyl-1,4,5-trihydroxy-3-oxocyclohexane-1-carboxylic acid, 3,4-DIHYDROXY-2-[(2,3,4,5,6-PENTAFLUOROPHENYL)METHYL]BENZOIC ACID, 3-DEHYDROQUINATE DEHYDRATASE, ... | 著者 | Otero, J.M, Llamas-Saiz, A.L, Santiago, C, Lamb, H, Hawkins, A.R, Maneiro, M, Peon, A, Gonzalez-Bello, C, van Raaij, M.J. | 登録日 | 2014-09-18 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Investigation of the Dehydratation Mechanism Catalyzed by the Type II Dehydroquinase To be Published
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4US1
 
 | The crystal structure of H-Ras and SOS in complex with ligands | 分子名称: | (3S)-3-[3-(aminomethyl)phenyl]-1-ethylpyrrolidine-2,5-dione, GTPASE HRAS, SON OF SEVENLESS HOMOLOG 1 | 著者 | Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. | 登録日 | 2014-07-02 | 公開日 | 2015-03-04 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
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1KVD
 
 | KILLER TOXIN FROM HALOTOLERANT YEAST | 分子名称: | SMK TOXIN, SULFATE ION | 著者 | Kashiwagi, T, Kunishima, N, Suzuki, C, Tsuchiya, F, Nikkuni, S, Arata, Y, Morikawa, K. | 登録日 | 1996-10-04 | 公開日 | 1997-04-01 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The novel acidophilic structure of the killer toxin from halotolerant yeast demonstrates remarkable folding similarity with a fungal killer toxin. Structure, 5, 1997
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1KBS
 
 | SOLUTION STRUCTURE OF CARDIOTOXIN IV, NMR, 1 STRUCTURE | 分子名称: | CTX IV | 著者 | Jeng, J.Y, Kumar, T.K.S, Jayaraman, G, Yu, C. | 登録日 | 1996-07-22 | 公開日 | 1997-07-23 | 最終更新日 | 2024-11-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Comparison of the hemolytic activity and solution structures of two snake venom cardiotoxin analogues which only differ in their N-terminal amino acid. Biochemistry, 36, 1997
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1KBT
 
 | SOLUTION STRUCTURE OF CARDIOTOXIN IV, NMR, 12 STRUCTURES | 分子名称: | CTX IV | 著者 | Jeng, J.Y, Kumar, T.K.S, Jayaraman, G, Yu, C. | 登録日 | 1996-07-22 | 公開日 | 1997-07-23 | 最終更新日 | 2024-10-30 | 実験手法 | SOLUTION NMR | 主引用文献 | Comparison of the hemolytic activity and solution structures of two snake venom cardiotoxin analogues which only differ in their N-terminal amino acid. Biochemistry, 36, 1997
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4URW
 
 | The crystal structure of H-Ras and SOS in complex with ligands | 分子名称: | 2-(2,6-DIMETHYLPHENYL)-4-(METHYLSULFANYL)-6-(PIPERAZIN-1-YL)-1,3,5-TRIAZINE, GTPASE HRAS, SON OF SEVENLESS HOMOLOG 1 | 著者 | Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. | 登録日 | 2014-07-02 | 公開日 | 2015-03-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
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6T7K
 
 | Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline | 分子名称: | 1,2-ETHANEDIOL, PROLINE, Proline--tRNA ligase, ... | 著者 | Johansson, C, Wang, J, Tye, M, Payne, N.C, Mazitschek, R, Thompson, A, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. | 登録日 | 2019-10-22 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline To Be Published
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1L2O
 
 | SCALLOP MYOSIN S1-ADP-p-PDM IN THE ACTIN-DETACHED CONFORMATION | 分子名称: | 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | 著者 | Himmel, M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. | 登録日 | 2002-02-22 | 公開日 | 2002-10-30 | 最終更新日 | 2024-12-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc.Natl.Acad.Sci.USA, 99, 2002
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1LNL
 
 | Structure of deoxygenated hemocyanin from Rapana thomasiana | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, hemocyanin | 著者 | Perbandt, M, Guthoehrlein, E.W, Rypniewski, W, Idakieva, K, Stoeva, S, Voelter, W, Genov, N, Betzel, C. | 登録日 | 2002-05-03 | 公開日 | 2003-06-03 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | The structure of a functional unit from the wall of a gastropod hemocyanin offers a possible mechanism for cooperativity Biochemistry, 42, 2003
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4URY
 
 | The crystal structure of H-Ras and SOS in complex with ligands | 分子名称: | GTPASE HRAS, N-[(4-aminophenyl)sulfonyl]cyclopropanecarboxamide, SON OF SEVENLESS HOMOLOG 1 | 著者 | Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. | 登録日 | 2014-07-02 | 公開日 | 2015-03-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
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6EY0
 
 | N-terminal part (residues 30-212) of PorM with the llama nanobody nb01 | 分子名称: | T9SS component cytoplasmic membrane protein PorM, llama nanobody nb01 | 著者 | Leone, P, Roche, J, Cambillau, C, Roussel, A. | 登録日 | 2017-11-10 | 公開日 | 2018-02-07 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Type IX secretion system PorM and gliding machinery GldM form arches spanning the periplasmic space. Nat Commun, 9, 2018
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8A5T
 
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6TG6
 
 | Toprim domain of RNase M5 | 分子名称: | Ribonuclease M5 | 著者 | Oerum, S, Catala, M, Tisne, C. | 登録日 | 2019-11-15 | 公開日 | 2020-09-23 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs. Mol.Cell, 80, 2020
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4CWP
 
 | Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor | 分子名称: | 5-(1,3-benzodioxol-5-ylmethyl)[1,2,4]triazolo[1,5-c]quinazolin-2-amine, HEAT SHOCK PROTEIN HSP 90-ALPHA | 著者 | Casale, E, Amboldi, N, Brasca, G, Caronni, D, Colombo, N, Dalvit, C, Felder, E.R, Fogliatto, G, Isacchi, A, Mantegani, S, Polucci, P, Riceputi, L, Sola, F, Visco, C, Zuccotto, F, Casuscelli, F. | 登録日 | 2014-04-03 | 公開日 | 2014-07-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Fragment-Based Hit Discovery and Structure-Based Optimization of Aminotriazoloquinazolines as Novel Hsp90 Inhibitors. Bioorg.Med.Chem., 22, 2014
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4CWR
 
 | Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor | 分子名称: | 5-(1,3-benzodioxol-5-ylmethyl)-10-fluoro[1,2,4]triazolo[1,5-c]quinazolin-2-amine, HEAT SHOCK PROTEIN HSP 90-ALPHA | 著者 | Casale, E, Amboldi, N, Brasca, G, Caronni, D, Colombo, N, Dalvit, C, Felder, E.R, Fogliatto, G, Isacchi, A, Mantegani, S, Polucci, P, Riceputi, L, Sola, F, Visco, C, Zuccotto, F, Casuscelli, F. | 登録日 | 2014-04-03 | 公開日 | 2014-07-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Fragment-Based Hit Discovery and Structure-Based Optimization of Aminotriazoloquinazolines as Novel Hsp90 Inhibitors. Bioorg.Med.Chem., 22, 2014
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4CWS
 
 | Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor | 分子名称: | 2-{[2-amino-5-(1,3-benzodioxol-5-ylmethyl)[1,2,4]triazolo[1,5-c]quinazolin-8-yl]amino}ethanol, HEAT SHOCK PROTEIN HSP 90-ALPHA | 著者 | Casale, E, Amboldi, N, Brasca, G, Caronni, D, Colombo, N, Dalvit, C, Felder, E.R, Fogliatto, G, Isacchi, A, Mantegani, S, Polucci, P, Riceputi, L, Sola, F, Visco, C, Zuccotto, F, Casuscelli, F. | 登録日 | 2014-04-03 | 公開日 | 2014-07-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Fragment-Based Hit Discovery and Structure-Based Optimization of Aminotriazoloquinazolines as Novel Hsp90 Inhibitors. Bioorg.Med.Chem., 22, 2014
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1LNX
 
 | Crystal structure of the P.aerophilum SmAP1 heptamer in a new crystal form (C2221) | 分子名称: | ACETIC ACID, GLYCEROL, URIDINE, ... | 著者 | Mura, C, Kozhukhovsky, A, Eisenberg, D. | 登録日 | 2002-05-04 | 公開日 | 2003-03-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs) Protein Sci., 12, 2003
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