5TYF
| DNA Polymerase Mu Product Complex, 10 mM Mg2+ (270 min) | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Jamsen, J.A, Wilson, S.H. | 登録日 | 2016-11-19 | 公開日 | 2017-08-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.971 Å) | 主引用文献 | Time-lapse crystallography snapshots of a double-strand break repair polymerase in action. Nat Commun, 8, 2017
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5TYW
| DNA Polymerase Mu Reactant Complex, Mn2+ (10 min) | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Jamsen, J.A, Wilson, S.H. | 登録日 | 2016-11-21 | 公開日 | 2017-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Time-lapse crystallography snapshots of a double-strand break repair polymerase in action. Nat Commun, 8, 2017
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5TYI
| Grb7 SH2 with bicyclic peptide containing pY mimetic | 分子名称: | Growth factor receptor-bound protein 7, Peptide inhibitor | 著者 | Watson, G.M, Wilce, M.C.J, Wilce, J.A. | 登録日 | 2016-11-20 | 公開日 | 2017-11-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target. J. Med. Chem., 60, 2017
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4ZV6
| Crystal structure of the artificial alpharep-7 octarellinV.1 complex | 分子名称: | AlphaRep-7, Octarellin V.1 | 著者 | Figueroa, M, Sleutel, M, Urvoas, A, Valerio-Lepiniec, M, Minard, P, Martial, J.A, van de Weerdt, C. | 登録日 | 2015-05-18 | 公開日 | 2016-05-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools. J.Struct.Biol., 195, 2016
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5A9J
| Crystal structure of the Helicase domain of human DNA polymerase theta, apo-form | 分子名称: | DNA POLYMERASE THETA | 著者 | Newman, J.A, Cooper, C.D.O, Aitkenhead, H, Pinkas, D.M, Kupinska, K, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2015-07-21 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | 主引用文献 | Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. Structure, 23, 2015
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5AIF
| Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot spring metagenomic libraries. Tomsk-sample-Native | 分子名称: | IMIDAZOLE, LIMONENE-1,2-EPOXIDE HYDROLASE | 著者 | Ferrandi, E, Sayer, C, Isupov, M.N, Annovazzi, C, Marchesi, C, Iacobone, G, Peng, X, Bonch-Osmolovskaya, E, Wohlgemuth, R, Littlechild, J.A, Montia, D. | 登録日 | 2015-02-13 | 公開日 | 2015-06-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Discovery and Characterization of Thermophilic Limonene-1,2-Epoxide Hydrolases from Hot Spring Metagenomic Libraries FEBS J., 282, 2015
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5UYZ
| Structure of Human T-complex protein 1 subunit epsilon (CCT5) mutant His147Arg | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, T-complex protein 1 subunit epsilon | 著者 | Pereira, J.H, McAndrew, R.P, Sergeeva, O.A, Ralston, C.Y, King, J.A, Adams, P.D. | 登録日 | 2017-02-24 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy. Sci Rep, 7, 2017
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5A9F
| Crystal structure of the Helicase domain of human DNA polymerase theta in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA POLYMERASE THETA, MAGNESIUM ION, ... | 著者 | Newman, J.A, Cooper, C.D.O, Aitkenhead, H, Pinkas, D.M, Kupinska, K, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2015-07-21 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. Structure, 23, 2015
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5UYX
| Structure of Human T-complex protein 1 subunit epsilon (CCT5) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit epsilon | 著者 | Pereira, J.H, McAndrew, R.P, Sergeeva, O.A, Ralston, C.Y, King, J.A, Adams, P.D. | 登録日 | 2017-02-24 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy. Sci Rep, 7, 2017
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4A8I
| Protein crystallization and microgravity: glucose isomerase crystals grown during the PCDF-PROTEIN mission | 分子名称: | 1,2-ETHANEDIOL, COBALT (II) ION, XYLOSE ISOMERASE | 著者 | Decanniere, K, Patino-Lopez, L.-D, Sleutel, M, Evrard, C, Van De Weerdt, C, Haumont, E, Gavira, J.A, Otalora, F, Maes, D. | 登録日 | 2011-11-21 | 公開日 | 2011-11-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Protein Crystallization and Microgravity: Glucose Isomerase Crystals Grown During the Pcdf-Protein Mission To be Published
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5A8A
| Crystal structure of the riboflavin kinase module of FAD synthetase from Corynebacterium ammoniagenes in complex with FMN and ADP (P3 2 21) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | 著者 | Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Medina, M. | 登録日 | 2015-07-13 | 公開日 | 2015-12-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Insights Into the Synthesis of Fmn in Prokaryotic Organisms. Acta Crystallogr.,Sect.D, 71, 2015
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4AL6
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5AA3
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5VGB
| Crystal structure of NmeCas9 HNH domain bound to anti-CRISPR AcrIIC1 | 分子名称: | Anti-CRISPR protein (AcrIIC1), CRISPR-associated endonuclease Cas9, GLYCEROL, ... | 著者 | Harrington, L.B, Doxzen, K.W, Ma, E, Knott, G.J, Kranzusch, P.J, Doudna, J.A. | 登録日 | 2017-04-10 | 公開日 | 2017-08-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.497 Å) | 主引用文献 | A Broad-Spectrum Inhibitor of CRISPR-Cas9. Cell, 170, 2017
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5AG7
| CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A BENZOMORPHOLINE LIGAND | 分子名称: | GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA, ethyl (3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetate | 著者 | Robinson, D.A, Spinks, D, Smith, V.C, Thompson, S, Smith, A, Torrie, L.S, McElroy, S.P, Brand, S, Brenk, R, Frearson, J.A, Read, K.D, Wyatt, P.G, Gilbert, I.H. | 登録日 | 2015-01-29 | 公開日 | 2015-10-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode. Chemmedchem, 10, 2015
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5VPP
| The 70S P-site tRNA SufA6 complex | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | 登録日 | 2017-05-05 | 公開日 | 2018-09-26 | 最終更新日 | 2018-11-07 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4A3S
| Crystal structure of PFK from Bacillus subtilis | 分子名称: | 6-PHOSPHOFRUCTOKINASE | 著者 | Newman, J.A, Hewitt, L, Rodrigues, C, Solovyova, A.S, Harwood, C.R, Lewis, R.J. | 登録日 | 2011-10-04 | 公開日 | 2012-08-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Dissection of the Network of Interactions that Links RNA Processing with Glycolysis in the Bacillus Subtilis Degradosome. J.Mol.Biol., 416, 2012
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5VFC
| WDR5 bound to inhibitor MM-589 | 分子名称: | 1,2-ETHANEDIOL, N-{(3R,6S,9S,12R)-6-ethyl-12-methyl-9-[3-(N'-methylcarbamimidamido)propyl]-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetraazacyclotetradecan-12-yl}-2-methylpropanamide, SULFATE ION, ... | 著者 | Stuckey, J.A. | 登録日 | 2017-04-07 | 公開日 | 2017-06-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction. J. Med. Chem., 60, 2017
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4ZT9
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4A3R
| Crystal structure of Enolase from Bacillus subtilis. | 分子名称: | CITRIC ACID, ENOLASE, SODIUM ION | 著者 | Newman, J.A, Hewitt, L, Rodrigues, C, Solovyova, A.S, Harwood, C.R, Lewis, R.J. | 登録日 | 2011-10-04 | 公開日 | 2012-08-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Dissection of the Network of Interactions that Links RNA Processing with Glycolysis in the Bacillus Subtilis Degradosome. J.Mol.Biol., 416, 2012
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5AGA
| Crystal structure of the Helicase domain of human DNA polymerase theta in complex with AMPPNP | 分子名称: | CITRATE ANION, DNA POLYMERASE THETA, MAGNESIUM ION, ... | 著者 | Newman, J.A, Cooper, C.D.O, Aitkenhead, H, Pinkas, D.M, Kupinska, K, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2015-01-29 | 公開日 | 2015-02-25 | 最終更新日 | 2015-12-16 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. Structure, 23, 2015
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5VFX
| Structure of an accessory protein of the pCW3 relaxosome in complex with the origin of transfer (oriT) DNA | 分子名称: | TcpK, oriT | 著者 | Traore, D.A.K, Wisniewski, J.A, Flanigan, S.F, Conroy, P.J, Panjikar, S, Mok, Y.-F, Lao, C, Griffin, M.D.W, Adams, V, Rood, J.I, Whisstock, J.C. | 登録日 | 2017-04-10 | 公開日 | 2018-04-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3. Nat Commun, 9, 2018
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5A5X
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5A9K
| Structural basis for DNA strand separation by a hexameric replicative helicase | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, REPLICATION PROTEIN E1 | 著者 | Chaban, Y, Stead, J.A, Ryzhenkova, K, Whelan, F, Lamber, K, Antson, F, Sanders, C.M, Orlova, E.V. | 登録日 | 2015-07-21 | 公開日 | 2015-08-26 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (19 Å) | 主引用文献 | Structural Basis for DNA Strand Separation by a Hexameric Replicative Helicase. Nucleic Acids Res., 43, 2015
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5VMQ
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