5AGA

Crystal structure of the Helicase domain of human DNA polymerase theta in complex with AMPPNP

Summary for 5AGA

Entry DOI	10.2210/pdb5aga/pdb
Descriptor	DNA POLYMERASE THETA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, CITRATE ANION, ... (6 entities in total)
Functional Keywords	transferase, polq, dna repair
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus : O75417
Total number of polymer chains	1
Total formula weight	93959.89
Authors	Newman, J.A.,Cooper, C.D.O.,Aitkenhead, H.,Pinkas, D.M.,Kupinska, K.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2015-01-29, release date: 2015-02-25, Last modification date: 2015-12-16)
Primary citation	Newman, J.A.,Cooper, C.D.O.,Aitkenhead, H.,Gileadi, O. Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. Structure, 23:2319-, 2015 Cited by PubMed: 26636256 DOI: 10.1016/J.STR.2015.10.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation