5AGA

Crystal structure of the Helicase domain of human DNA polymerase theta in complex with AMPPNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005524	molecular_function	ATP binding
A	0006261	biological_process	DNA-templated DNA replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ANP A 1892

Chain	Residue
A	VAL89
A	LEU123
A	MG1895
A	LYS91
A	GLN96
A	THR117
A	SER118
A	ALA119
A	GLY120
A	LYS121
A	THR122

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FLC A 1893

Chain	Residue
A	PRO410
A	TRP411
A	GLY412

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K A 1894

Chain	Residue
A	PHE787
A	VAL797
A	VAL799
A	SER800
A	LEU802

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 1895

Chain	Residue
A	LYS121
A	ASP216
A	ANP1892

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:26636256, ECO:0007744|PDB:5A9F, ECO:0007744|PDB:5AGA

Chain	Residue	Details
A	GLN96

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00541, ECO:0000305|PubMed:26636256, ECO:0007744|PDB:5A9F, ECO:0007744|PDB:5AGA

Chain	Residue	Details
A	ALA115

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