5A9F

Crystal structure of the Helicase domain of human DNA polymerase theta in complex with ADP

Summary for 5A9F

• Entry DOI: 10.2210/pdb5a9f/pdb
• Related: 5A9J
• Descriptor: DNA POLYMERASE THETA, ADENOSINE-5'-DIPHOSPHATE, POTASSIUM ION, ... (4 entities in total)
• Functional Keywords: transferase, polymerase, helicase, polq, dna repair
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus : O75417
• Total number of polymer chains: 1
• Total formula weight: 93691.79

Authors

Newman, J.A.,Cooper, C.D.O.,Aitkenhead, H.,Pinkas, D.M.,Kupinska, K.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2015-07-21, release date: 2015-12-16, Last modification date: 2024-01-10)

• Primary citation: Newman, J.A.,Cooper, C.D.O.,Aitkenhead, H.,Gileadi, O.; Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.; Structure, 23:2319-, 2015; PubMed: 26636256; DOI: 10.1016/J.STR.2015.10.014

Experimental method

X-RAY DIFFRACTION (3.2 Å)